Cell Cycle

Question 1

What are the three different types of cells in terms of regeneration potential?

Answer 1

Permanent cells (fat cells)
Stable cells (potential to divide when signals - hepatocytes)
Labile Cells (continue to divide throughout live - bone marrow cells, skin)

Question 2

What occurs in G1?

Answer 2

Rate of cell proliferation of most mammalian cells is regulated through G1 transit

Question 3

What is S?

Answer 3

initiation of DNA synthesis (euchromatin then heterochromatin)

Question 4

What is G2?

Answer 4

Synthesis for proteins required for mitosis

Question 5

What is M phase?

Answer 5

Mitosis

Question 6

What is progeria?

Answer 6

Pre-mature aging, due to less frequent cell division

Question 7

What are the benefits of frog eggs?

Answer 7

Large size, easy to inject substances, rapid division, isolated maturation promoting factor (MPF)

Question 8

What is associated with cyclin concentration?

Answer 8

MPF activity

Question 9

What does MPF do?

Answer 9

Promotes cell division

Question 10

What + What = MPF?

Answer 10

Cyclin B + Cdc2 Kinase

Question 11

Are CDKs important?

Answer 11

Yes….

Question 12

What is the cell cycle regulation based on?

Answer 12

Cyclically activated protein kinases, multiple cdks and cyclines regulate passage of cells through the cycle.