Cell Cycle Flashcards

1
Q

New cells arise as a result of three intricate processes:

A

Synthesis and replication of chromosomes, division of the nucleus (Mitosis), and cell division/cytokinesis.

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2
Q

What are the two primary phases of the cell cycle of mitosis?

A

Interphase and Mitotic Phase

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3
Q

Mitosis results in what kind of daughter cells?

A

Identical daughter cells

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4
Q

What is the purpose of mitosis?

A

To produce new cells for growth and for the replacement of worn out cells

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5
Q

The stage of the cell cycle where DNA replication occurs is…

A

Interphase

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6
Q

What occurs in late interphase?

A

Chromosomes have replicated but are so extended that they cannot be seen individually, making them chromatin

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7
Q

What occurs in Prophase?

A

Chromosomes shorten and thicken. Each replicated chromosome becomes visible as a pair of sisterchromatids joined by a duplicated but unseparated centromeere which attaches to the spindle fibres.

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8
Q

What do centrioles do?

A

Produce spindle fibres

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9
Q

What do spindle fibres do?

A

Attach to centromeres of chromatids and separate them

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10
Q

What occurs during Metaphase?

A

The spindle fibres align the sister chromatids along an imaginary equator half way in between the two centrioles at the opposite end of the cell.

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11
Q

What is Anaphase?

A

When the two sister chromatids separate at their centromeres giving rise to two daughter chromosomes which move toward opposite poles

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12
Q

What is Telophase?

A

The chromosomes uncoil and chromatin reforms. A nuclear membrane forms around each chromosome set and cytokinesis is underway

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13
Q

During mitosis, the nuclear membrane of a cell disappears and then re-forms respectively during…

A

Prophase and Telophase

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14
Q

What are adult somatic stem cells?

A

Undifferent cells found in tissues or organs with the primary role to replenish dying cells and regenerate damaged tissues

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15
Q

What are embryonic stem cells?

A

They come from the inner cell mass of early embryos or blastocysts that can eventually differentiate into specialized cells of the body

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16
Q

Diploid cells (2n) are produced from what cell cycle process?

A

Mitosis

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17
Q

Haploid cells (n) are produced by what cell cycle process?

A

Meiosis

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18
Q

How are identical twins formed?

A

Called mono zygotic twins, they arise from one fertilized egg

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19
Q

What are Dizygotic twins?

A

Come from two different eggs, fertilized by two different sperms and the zygotes then have different information (fraternal)

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20
Q

Meiosis is

A

The formation of gametes

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21
Q

Homologous pairs are found in what cell cycle?

A

Meiosis

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22
Q

What are gametes?

A

Egg and sperm

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23
Q

In meiosis, what happens to the chromosome number of originally 46 (of human)?

A

Reduced to half. In humans that would be 23

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24
Q

Human sex cells have 23 chromosomes and are considered…

A

Haploid (n)

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25
Somatic cells have 46 chromosome and are considered...
Diploid (2n)
26
Union of the egg and sperm (haploids) produce and zygote with....
46 chromosomes (diploid)
27
What does recombination of genes ensure?
Each offspring gets genetic information from each of the parents - variation is essential for natural selection.
28
What is natural selection?
Survival of the fittest
29
Mitosis after meiosis is for the sake of...
growth
30
How many pairs of chromosomes are found in a zygote/human?
23 pairs
31
How many pairs of chromosomes are homologous and what are they referred to as?
22, Autosomes
32
How many pairs of sex chromosomes are there and what is their purpose?
1 and they determine the gender
33
How is gender determined?
Females have two X chromosomes (XX), Men have one X and one Y (XY)
34
Are sex chromosome homologous?
No, even though they behave as though they are
35
In general, Meiosis involves:
A single DNA replication and two nuclear divisions
36
Homologous pairs separate during...
Meiosis 1
37
Sister chromatids separate during
Meiosis 2
38
The process of meiosis produces how many cells?
4
39
What occurs in prophase 1
chromosomes which have been replicated in Interphase now appear as sister chromatids attached by the centromere. Tetrads form allowing crossing over to occur.
40
What occurs in Metaphase 1?
Homologous chromosomes align at the equatorial plate of the cell
41
What occurs in Anaphase 1?
Homologous chromosomes separate but sister chromatids stay together.
42
What occurs in Telophase 1?
Daughter cells contain only one chromosome of the homologous pair.
43
What does not happen in prophase 2?
DNA replication
44
What occurs in metaphase 2?
chromosomes align at the equatorial plate
45
What occurs in Anaphase 2?
The centromeres divide and sister chromatids separate and move to each pole
46
What occurs in telophase 2?
Cell division is complete with the production of 4 haploid daughter cells
47
Mitosis only occurs in...
Somatic cells
48
Meiosis only occurs in...
Ovaries and Testes
49
How many daughter cells are produced for Meiosis and Mitosis?
Mitosis = 2, Meiosis = 4
50
In meiosis, daughter cells are the same as parent cells. True of False?
False
51
How many divisions are in the mitotic cycle?
1
52
Does crossing over occur in mitosis?
no
53
The term for gamete formation is...
Gametogenisis
54
Two meiotic divisions in females do not result in four equally mature gametes as in male, but...
One large ovum that requires the nutrients and organelles for possible future divisions from the 2-3 polar bodies.
55
What happens to the used polar bodies?
they are usually discarded.
56
Unequal cleavage occurs in
Oogenisis
57
Equal cleavage occurs in
Spermatogensis
58
What is Nondisjunction?
When homologous chromosomes do not separate during meiosis and instead, move to the same pole
59
What happens what nondisjunction occurs?
Gametes end up with more or less than the required number of chromosomes making cells lack of have too much genetic information to function properly
60
In humans, non disjunction produces gametes with (#s)
22 or 24 chromosomes
61
A zygote with three chromosomes in place of the normal pair is called
Trisomy
62
A zygote that has a single chromosome in place of a homologous pair is called
Monosomy
63
What is a karyotype?
The pictures of arranged homologous pairs
64
What is Chorion Villus Sampling or Biopsy?
cells from the outer membrane of the embryo are removed and used for karyotyping to detect chromosomal disorders
65
What is Amniocentesis
The using of a syringe to draw amniotic fluid which contains cells from the fetus allowing karyotypes to be prepared and analyzed to detect chromosomal abnormalities.