CELL CYCLE

Question 1

what are the phases of the cell cycle?

Answer 1

G1 - growth and metabolic roles
S - DNA replication
G2 - growth and mitotic preparation
M - prophase, metaphase, anaphase, telophase

Question 2

why is the cell cycle important?

Answer 2

it allows for cell replication, development, and repair

Question 3

what is the G0 phase?

Answer 3

phase for cells that are not actively dividing or preparing to; resting phase

Question 4

what experiment led to the discovery of MPFs?

Answer 4

maturation promoting factors were discovered in frog oocytes - they would stay arrested in G2 phase until progesterone signaled for mitosis

Question 5

what experiment led to the discovery of CDKs?

Answer 5

temperature experiments in yeast allowed for the finding of the gene cdc28, which encodes for CDKs - it’s a necessary gene for cell division

Question 6

what experiment led to the discovery of cyclins?

Answer 6

protein synthesis inhibition research on sea urchins

Question 7

what is MPF and what role does it play?

Answer 7

maturation promoting factors are composed of cyclin B and CDK1; regulates cell cycle by promoting transition from G2 to M