cell cycle Flashcards

1
Q

cell cycle

A

period of time betweeen the birth of a cell and its own divission to produce two new daughter cells

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2
Q

cycling cells

A

Cells that continue to divide regularly in definite intervals

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3
Q

what do cyclins activate

A

cyclin dependant kinases- cdks

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4
Q

what happens to cyclins and cdks at the end of the cell cycle

A

they are dgeraded

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5
Q

cyclins role

A

regulate cell cycle progression

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6
Q

ubiquitin

A

takes up used molecules
is a care taker protein

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7
Q

interphase

A

The interval between the end of mitosis and beginning of next

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8
Q

s phase

A

period in which new dna is synthesised

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9
Q

what is the s phase promoted by

A

cyclin a and cdks

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10
Q

longest phase

A

g1

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11
Q

g1

A

cell mostly grows

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12
Q

does g1 have a checkpoint

A

yes

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13
Q

if dna is damaged what happens

A

enters g0 phase where it is either repaired or carries out apoptosis

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14
Q

when does dna replication occur

A

s phase

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15
Q

what occurs during s phase

A

Each chromosome from g1 is replicated with help from enzymes, energy and structural proteins
Chromatid copied and pasted
Join at centromere
Still make up a single chromosome; amount of info doubled

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16
Q

are more chromosomes made

A

no just more infomration is added

17
Q

g2 phase

A

second growth phase
cell duplicates organelles

18
Q

what happens post g2 phase

A

must pass g2 checkpoint to enter mitosis

19
Q

karyokinesis

A

dna seperated into 2 distinct nuceli

20
Q

cytokinesis

A

seperates daughter cells into 2 distinct cells

21
Q

prophase

A

nuclear membrane disintegrates and chromosomes condense and become visible
2 centromeres migrate to opposite ends

22
Q

metaphase

A

chromosomes migrate to middle of cell on metaphase plate
once in plane each centrosome sends out thread like prokections

23
Q

spindle fibres

A

the thread like projections that centrosomes send out to centromeres

24
Q

anaphase

A

centrosome starts pulling on spindle fibres to pull chromatids apart
sister chromatids seperate

25
Q

telophase

A

nuclear membranes form around chromosome
cytokinesis ; cell membrane pinches until 2 daughters seperate

26
Q

when does crossing over occur

A

prohase 1

27
Q

what is g1 controlled by

A

cyclin e and cdks

28
Q

what controls g2 phase

A

cyclin b and cdks

29
Q

where does mitosis occur

A

somatic cells

30
Q

colchicine

A

arrests the cell division at metaphase
prevents formation of microtubules of the spindle

31
Q

non disjunction

A

Due to abnormal function of spindle apparatus one or more chromosomes fail to migrate properly in anaphase

one daughter cell recieves extra chromosomes and other daughter cell is deficient inthis chromosome

32
Q

isochromosome

A

Sometimes, the centromere splits transversely instead of longitudinal division.
This leads to formation of two daughter chromosome of unequal length

33
Q

when does the nucleolus appear

A

telophase

34
Q

when do chromosomes become uncoiled and lose their indiviudal identity

A

telophase

35
Q
A