Cell Cycle Flashcards
1
Q
What are the three phases of interphase?
A
G1, S, G2
2
Q
What are the two parts of the cell cycle other than interphase?
A
Mitosis (nucleus splits), cytokinesis (cytoplasm splits)
3
Q
What happens in G1 and G2?
A
- Organelles replicate
- Cell size increase
- Protein synthesis
- Respiration
4
Q
What happens in the synthesis phase?
A
DNA replication (only in s phase)
5
Q
What are the 3 checkpoints?
A
- G1 checkpoint
- G2 checkpoint
- Spindle assembly checkpoint
6
Q
What does the G1 checkpoint check for?
A
- Cell size
- DNA damage
7
Q
What happens if the requirements of this checkpoint are not satisfied and what may this be due to?
A
The cell goes to a resting state and leaves the cell cycle (G0)
Due to - Differentiation
- DNA Damage
8
Q
What does the G2 checkpoint check for?
A
DNA replication error
And same checks at G1
9
Q
Where does the spindle fibre checkpoint take place and what does it check for?
A
- At mitosis
- Check for chromosome attachment to spindle
