Cell Cycle

Question 1

Senescent

Answer 1

Cells that stop dividing due to old age

Question 2

Stages of cell division

Answer 2

1.Interphase
2.Mitotic phase

Question 3

Interphase duration

Answer 3

15-23 hours

Question 4

Gene expression occurs during ___ and NOT ___

Answer 4

Interphase, m phase

Question 5

Cells that permanently stay at G0

Answer 5

Nerve and heart cells

Question 6

Cells that stay in G0 semi permanently

Answer 6

Liver and kidney cells

Question 7

Cells that rarely enter G0 and continue dividing

Answer 7

Hematopoietic cells and intestinal epithelial cells

Question 8

During G1

Answer 8

1.Cellular Growth
2.Synthesis of RNA and proteins

Question 9

During S phase

Answer 9

DNA synthesis and chromosome replication

Question 10

In which phase does the cell have double its DNA content?

Answer 10

S phase

Question 11

During G2

Answer 11

1.Cellular growth
2.DNA checked for errors

Question 12

Cell cycle check points

Answer 12

. G1 checkpoint
.G2 checkpoint
.M spindle checkpoint

Question 13

Why does the cell cycle move in one direction and is irreversible?

Answer 13

Because of the regulated degradation of proteins

Question 14

Cyclin–cdk complexes
D-
E-
A-
B-

Answer 14

D-cdk 4,6
E-cdk2
A-cdk2
B-cdk 1

Question 15

Main cell cycle controllers

Answer 15

Cyclins and cdks

Question 16

Cyclin D cdk 4,6 job

Answer 16

G1 cyclin,cdk that phosphorylation Rb to shift the cell from G1 to S

Question 17

Cyclin E, cdk 2 job

Answer 17

G1 cyclin…Prepares cell for S phase

Question 18

Cyclin A,cdk 2 job

Answer 18

S phase
Activates DNA replication

Question 19

MPF [mitotic cyclin,cdks] job
Cyclin B,cdk 1

Answer 19

G2, progresses the cell from G2 checkpoint to M phase

Question 20

Cdk regulation mechanisma

Answer 20

.Cyclins (cdk activators)
.Cdk inhibitors
.Activating phosphorylation
.İnhibitory phosphorylation

Question 21

Cyclin B cdk 1 job

Answer 21

Mitosis