Cell Cycle Flashcards

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1
Q

Interphase

A

period between mitotic divisions

G1
S
G2

18-24 hours in lab cells

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2
Q

Mitosis

A

cell division that produces 2 cells

usually less than 1 hour in lab cells

Prophase
Metaphase
Anaphase
Telophase

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3
Q

Cytokinesis

A

cleavage furrow forms and deepens

cytoplasmic division

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4
Q

Stages of cell cycle

A

interphase
mitosis
cytokinesis

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5
Q

G0

A

inactive stage between cytokinesis and G1

white blood cells enter G0, later reenter G1, and divide

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6
Q

G1

A

immediately after mitosis
cell growth BEFORE DNA replication
production of cytoplasmic components like organelles, ribosomes, membranes, RNA
cell size doubles

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7
Q

S (synthesis)

A

DNA replication = chromosomes duplicated

sister chromatids form

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8
Q

G2

A

cell becomes ready to divide
mitochondria divide
precursors of spindle fibers synthesized

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9
Q

Prophase

A

PREPARE
chromosomes condense and become visible
nuclear envelope disappears
centrioles divide, migrate to opposite poles of cell
spindle fibers form and attach to chromosomes, stretch across the cell

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10
Q

Metaphase

A

chromosomes line up on the MIDDLE of cell

46 centromeres, each attached to 2 sister chromatids

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11
Q

Anaphase

A

APART
chromosomes begin to separate
each sister chromatid is converted into a chromosome
briefest stage, but ensures each cell receives an identical set of 46 chromosomes.

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12
Q

Telophase

A

chromosomes reach opposite poles and decondense
spindle fibers break down
new nuclear envelope forms
mitosis is completed

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13
Q

Meiosis

A

one cycle of chromosomal replication followed by 2 successive cell divisions = 4 haploid cells
homologous chromosomes

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14
Q

Reduction division

A

chromosome number reduced to half (46 to 23, diploid to haploid)
meiosis I

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15
Q

Prophase I of Meiosis

A

each chromosome pairs with its homologue
crossing over
spindle microtubules attach to each chromosome

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16
Q

Metaphase I of Meiosis

A

chromosomes and spindle poles move apart, into position midway between poles

17
Q

Anaphase I of Meiosis

A

homologous partners move to opposite poles

18
Q

Telophase I of Meiosis

A

cytoplasmic divison to produce 2 haploid cells, with one of each chromosome type
chromosomes are still in the DUPLICATED state

19
Q

Prophase II of Meiosis

A

microtubules attach to the chromosomes

20
Q

Interkinesis (Meiosis)

A

no DNA replication between two nuclear divisions

21
Q

Metaphase II of Meiosis

A

duplicated chromosomes positioned midway between the two poles

22
Q

Anaphase II of Meiosis

A

sister chromatids of each chromosome move to opposite spindle poles
each ‘sister’ chromatid is now a chromosome

23
Q

Telophase II of Meiosis

A

4 haploid daughter nuclei produced

all chromosomes are now in the unduplicated state.

24
Q

Spermatogenesis

A

primary spermatocytes enter meiosis
after meiosis i = secondary spermatocytes
after meiosis ii = haploid spermatids, undergo changes and become mature sperm

25
Q

Oogenesis

A

primary oocytes enter meiosis during embryonic development, arrest in meiosis i
one oocyte per menstrual cycle completes meiosis i just before ovulation
haploid secondary oocyte is formed, along with a polar body (nonfunctional)
if secondary oocyte is fertilized, meiosis is completed (sperm stimulates meiosis ii)