Cell Communication & Signalling Flashcards
Release of neurotransmitter at terminal
a) direct
b) paracrine
c) endocrine
d) nerve conduction
e) neuroendocrine
d
Responsible for the propagation of AP
a) direct
b) paracrine
c) endocrine
d) nerve conduction
e) neuroendocrine
A
local release to nearby cells
a) direct
b) paracrine
c) endocrine
d) nerve conduction
e) neuroendocrine
PARACRINE
When the ligand is exocytosed in the ECF and is received by the same cell it came from is called
a) paracine
b) autocrine
c) endocrine
d) both a & b
b
T/F: Endocrine sytem uses hormones secreted to the lymphatic system to reach the target organs
F
T/F: Endocrine system also uses ligand via lympgatic systme
F
Important in immune responses
a) chemical signalling
b) membrane bound
c) gap
b
Direct cell to cell communication
a) chemical signalling
b) membrane bound
c) gap
c
Utilizes by paracrine and n.s
a) chemical signalling
b) membrane bound
c) gap
a
Endocrine uses what type of signalling
a) chemical signalling
b) membrane bound
c) gap
a
To pass cellular surface it must be
a) lipid soluble
b) water soluble
c) both
b
To pass the interior it must be
a) lipid soluble
b) water soluble
c) both
a
“cancer cell signalling”
a) receptor/ ion channel
b) G-protein-linked receptors
c) catalytic receptors
c
utilizes secondary messenger sytem
a) receptor/ ion channel
b) G-protein-linked receptors
c) catalytic receptors
b
the receptor is the effector itself
a) receptor/ ion channel
b) G-protein-linked receptors
c) catalytic receptors
a
G-protein- linked receptor
a) rapid
b) prolonged
c) no effect
b
‘primary ligand - gated receptor’
a) receptor/ ion channel
b) G-protein-linked receptors
c) catalytic receptors
a
ideal for neurotransmission
a) receptor/ ion channel
b) G-protein-linked receptors
c) catalytic receptors
a
Glycine receptor __ channel
a) Na
b) Cl
c) K
d) all of the above
b
Glutamate receptor __ channel
a) Na
b) Ca
c) K
d) all of the above
d
GlABA receptor __ channel
a) Na
b) Cl
c) K
d) all of the above
B
nICOTINIC aCH receptor __ channel
a) Na
b) Cl
c) K
d) all of the above
A
NMDA is __ receptor
i. ligand gated
ii. voltage gated
iii. mechanical
a) all of the above
b) i and ii is true
c) i and iii is true
d) ii and iii is true
b
Gs
a) activates Phospholipase C = IP3 & DAG
b) converts light to electrical signals
c) K+ ion channel-linked (in CNS)
d) adenylate cyclase to produce cAMP
a
