Cell Communication & Signalling Flashcards

1
Q

Release of neurotransmitter at terminal

a) direct
b) paracrine
c) endocrine
d) nerve conduction
e) neuroendocrine

A

d

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2
Q

Responsible for the propagation of AP

a) direct
b) paracrine
c) endocrine
d) nerve conduction
e) neuroendocrine

A

A

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3
Q

local release to nearby cells

a) direct
b) paracrine
c) endocrine
d) nerve conduction
e) neuroendocrine

A

PARACRINE

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4
Q

When the ligand is exocytosed in the ECF and is received by the same cell it came from is called

a) paracine
b) autocrine
c) endocrine
d) both a & b

A

b

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5
Q

T/F: Endocrine sytem uses hormones secreted to the lymphatic system to reach the target organs

A

F

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6
Q

T/F: Endocrine system also uses ligand via lympgatic systme

A

F

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7
Q

Important in immune responses

a) chemical signalling
b) membrane bound
c) gap

A

b

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8
Q

Direct cell to cell communication

a) chemical signalling
b) membrane bound
c) gap

A

c

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9
Q

Utilizes by paracrine and n.s

a) chemical signalling
b) membrane bound
c) gap

A

a

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10
Q

Endocrine uses what type of signalling

a) chemical signalling
b) membrane bound
c) gap

A

a

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11
Q

To pass cellular surface it must be

a) lipid soluble
b) water soluble
c) both

A

b

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12
Q

To pass the interior it must be

a) lipid soluble
b) water soluble
c) both

A

a

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13
Q

“cancer cell signalling”

a) receptor/ ion channel
b) G-protein-linked receptors
c) catalytic receptors

A

c

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14
Q

utilizes secondary messenger sytem

a) receptor/ ion channel
b) G-protein-linked receptors
c) catalytic receptors

A

b

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15
Q

the receptor is the effector itself

a) receptor/ ion channel
b) G-protein-linked receptors
c) catalytic receptors

A

a

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16
Q

G-protein- linked receptor

a) rapid
b) prolonged
c) no effect

A

b

17
Q

‘primary ligand - gated receptor’

a) receptor/ ion channel
b) G-protein-linked receptors
c) catalytic receptors

A

a

18
Q

ideal for neurotransmission

a) receptor/ ion channel
b) G-protein-linked receptors
c) catalytic receptors

A

a

19
Q

Glycine receptor __ channel

a) Na
b) Cl
c) K
d) all of the above

A

b

20
Q

Glutamate receptor __ channel

a) Na
b) Ca
c) K
d) all of the above

A

d

21
Q

GlABA receptor __ channel

a) Na
b) Cl
c) K
d) all of the above

A

B

22
Q

nICOTINIC aCH receptor __ channel

a) Na
b) Cl
c) K
d) all of the above

A

A

23
Q

NMDA is __ receptor

i. ligand gated
ii. voltage gated
iii. mechanical
a) all of the above
b) i and ii is true
c) i and iii is true
d) ii and iii is true

A

b

24
Q

Gs

a) activates Phospholipase C = IP3 & DAG
b) converts light to electrical signals
c) K+ ion channel-linked (in CNS)
d) adenylate cyclase to produce cAMP

A

a

25
Q

Gt

a) activates Phospholipase C = IP3 & DAG
b) converts light to electrical signals
c) K+ ion channel-linked (in CNS)
d) adenylate cyclase to produce cAMP

A

b

26
Q

Go

a) activates Phospholipase C = IP3 & DAG
b) converts light to electrical signals
c) K+ ion channel-linked (in CNS)
d) K+ ion channel-linked (in heart)

A

c

27
Q

t/f: G protein linked signalling serves to amplify the signal from a ligand

A

t

28
Q

t/f: It is G protein that stimulate directly an ion channel that activates the cells

A

f

29
Q

t/f: w/o ligand, receptor and ion channel are still activated

A

f