cell communication Flashcards
purpose of cell communication
- communication for development
- communication for homeostasis
- however communication breaks down in old age
characteristics of signals
- duration
- speed
- mechanism
- range
- specificity
- form of signal
contact-dependent communication
cell-to-cell direct communication
very short range
synaptic communication
communication via neurotransmitters along an axon
short-medium transport
paracrine communication
local transmission to surrounding cells via a local mediator
endocrine communication
hormones through bloodstream
types of response to signals
- be in form of gradient = morphogen gradient
- cells can react in different ways on the basis of the strength of the signal
possible downstream effects of receptor stimulation
metabolism for enzyme
gene expression
changes in cell shape/movement
factors affecting speed of response
- changing the structure of an existing protein eg. ion channel (very fast)
- changing the post translational modification eg phosphorylation (quite fast)
- changing protein levels via gene expression (slow)
how does signal regulation occur?
regulation of enzymes such as kinases and phosphatases which take part in mechanisms
- positive and negative feedback