Cell Biology & Neurophysiology Flashcards
What houses the insides of a cell?
- Semipermeable, lipid bilayer, plasma membrane
- Comprised of lipids, phosphate heads, and fatty acids
What is the purpose of the proteins in this housing?
- Connection of extra- and intracellular works to:
- Stabilize the cell membrane
- Anchoring cell membrane to adjacent cells
- Selective transport of ions and other large molecules
- Cellular motility
- Communication
How does a cell nucleus transport peptides or lipids?
- Peptides or lipids are manufactured in the ER
- There they are modified and folded
- Those that are properly folded are transported to the cis of the Golgi apparatus
- More modifications take place as the peptides or lipid pass from the cis to medial to trans Golgi
- At the trans Golgi apparatus, the peptides or lipids are packaged into vesicles and then sent to target sites
What do mitochondria do?
-Power the cell with the generation of ATP
What is a neuron?
- Basic cell of the nervous system
- Communication with muscles, glands, glial cells, etc. about the status of the body’s internal environment
- If a change is noticed, neurons send out signals to restore the internal environment to its homeostatic status
What are the 4 zones of a neuron?
- Input zone: dendrites
- Action zone: soma, cell body, axon hillock
- Transmission zone: axon
- Output zone: telodendria
An increase in discharge probability is what kind of input? Decrease?
- Increase: excitatory
- Decrease: inhibitory
Axons are covered in what? Why?
- Myelin shealth
- Prevent the diffusion of ions across the cell wall to speed up the conduction of APs down the axon
What is a synapse?
-Area between two neurons, comprised of terminal boutons, synaptic cleft, and membrane of the next neuronal cell
How do the short lived mini-potentials generate an action potential?
-When IPSPs and EPSPs temporarily add up, creating a depolarization near a neuron’s axon hillock, an AP is triggered
Describe the voltage and transfer of chemicals in an action potential.
- When IPSPs and EPSPs temporarily add up, creating a depolarization near a neuron’s axon hillock, an AP is triggered
- Ion channels open up, rapid influx of K+ into the negatively charged HCs
- Spike in voltage (AP)
- Positive ion channels then open so the K+ ions can leave the cell
- Voltage drops down below the resting potential and then returns back to resting potential