1
Q

Interference with genetic regulation of cell division can result in developmental abnormalities of anatomy and function and is a major factor in _____ development.

A

cancer

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2
Q

_____ is mitotic cell growth in which the tissue or organ increases in size by increasing the number of cells within it.

A

hyperplasia

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3
Q

_____ is the expansion of the size of each individual cell to increase from infant size to adult size.

A

hypertrophy

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4
Q

Give four examples of tissue or organ cells that continue to grow or replace themselves by mitosis and hyperplasia:

A
  1. skin
  2. liver
  3. bone marrow
  4. linings of the GI tract and blood vessels
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5
Q

Give three examples of tissue and organ cells that do not grow by mitosis after maturation, but grow by hypertrophy:

A
  1. cardiac muscle cells
  2. skeletal muscle cells
  3. neurons
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6
Q

Cells of an organ that grow by hypertrophy and die are replaced by _____ tissue, which decreases the functioning of that organ.

A

scar

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7
Q

The rate of cell division decreases with _____.

A

age

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8
Q

Cell aging in tissues capable of mitosis is determined by _____ mitosis, or the number of preprogrammed cell divisions it can undergo.

A

quantal

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9
Q

As the organ cells capable of mitosis age, wear out, are damaged, or become less functional in some way, they undergo a process of programmed cell death or cellular suicide, known as _____.

A

apoptosis

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10
Q

For optimum function, mitosis must be balanced with _____.

A

apoptosis

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11
Q

The structural appearance of normal cells reflects their _____.

A

function

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12
Q

All normal cells perform at least one specific job, called a _____ function, that helps whole-body function.

A

differentiated

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13
Q

_____ cells have more than one differentiated function.

A

liver

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14
Q

Cells of a tissue or organ have several different cell surface proteins that allow them to adhere tightly together called _____ _____ _____.

A

cell adhesion molecules (or CAMS)

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15
Q

Name two cells that do not produce cell adhesion molecules (CAMS) and do not adhere to each other:

A
  1. erythrocytes

2. leukocytes

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16
Q

_____ is a condition in which normal human somatic cells have a nucleus and are diploid, containing 23 pairs of human chromosomes.

A

euploidy

17
Q

The only normal mature human cells that are not diploid are _____, which have extruded the nucleus and do not contain any chromosomes, and mature _____ cells, which are _____, containing only half of each pair of chromosomes (23 total chromosomes).

A
  1. erythrocytes
  2. sex
  3. haploid
18
Q

Normal cells that have retained mitotic ability are _____ from mitosis when their membranes are completely in contact with the membranes or other cells, a condition known as _____ _____ _____ _____.

A
  1. inhibited
  2. contact
  3. inhibition
  4. of
  5. mitosis
19
Q

Contact inhibition of mitosis is also known as _____-_____ inhibition of cell _____.

A
  1. density
  2. dependent
  3. growth
20
Q

Normal cell populations are regulated by a balance between products produced by _____, which promote entering and completing the cell cycle.

A

oncogenes

21
Q

_____ _____ restrict or inhibit normal cells from entering and moving through the cell cycle.

A

Suppressor genes

22
Q

_____ products are pro mitotic and induce cells to divide.

A

Oncogene

23
Q

_____ _____ products inhibit all aspects of mitosis and also trigger apoptosis.

A

Suppressor gene