CELL AND TISSUES Flashcards
The basic structural and functional unit of life capable of performing series of physical and chemical processes necessary for their survival —metabolism
Cell
2 Phases of Metabolism
- Anabolism (Constructive phase)
- Catabolism (Destructive phase)
Anabolism (constructive phase)
Carbohydrate, protein, lipid, and steroid sythesis in RER and SER
Glycolysis/glycogen breakdown in the liver and skeletal muscle to produce glucose upon action of glucagon
Catabolism (destructive phase)
Collective term for different substances that make up a cell
Protoplasm
5 Basic Substances of Protoplasm
- Water/H2O
- Electrolytes
- Proteins
- Lipids
- Carbohydrates
Principal fluid medium, constituting 70-85% (3/4) of cell mass
Water/H2O
Provide inorganic chemical for cellular reactions
Electrolytes
Electrolytes (most important) (2)
- Cations
- Anions
Positively charged
Cations
Cations contain positive charges including: (4)
Na+, K+, Ca++, Mg++
Negatively charged
Anions
Anions contain negative charnges including: (4)
Cl-, HCO3-, PO4-,SO4-
Most abundant substance next to water, constituting 10-20% of cell mass
Proteins
2 Forms of proteins that gave been recognized
- Structural protein
- Globular protein
Fibrillar forms
Structural proteins
Composed of individual protein molecules and are usually globular forms
Globular proteins
Most important of which are phospholipids and cholesterol, constituting 2% of cell mass; are used to form cell membrane (lipid bilayer)
Lipids
Constituting 70-85% (3/4) of cell mass
Water
Costituting 10-20% of cell mass
Proteins
Constituting 2% of cell mass
Lipids
Under lipids is?
Triglycerides/neutral fats
Storage form of lipid in fat cells
Triglycerides/neutral fats
Have little structural function (glycocalyx of cell membrane) but provide most of the nutritional requirement of cell
Carbohydrates
Under carbohydrates are?
- Glucose
- Glycogen
Simplest form of carbohydrate for cellular metabolism and production of energy
Glucose
Storage form of carbohydrate in the liver, skeletal muscle (pancreas)
Glycogen
Parts of an Animal cell
- Cell membrane
- Nucleus
a. Chromosome/chromatin granule
b. Nucleolus
c. Nuclear envelope - Cytoplasm and its organelles
a. Mitochondrion
b. Lysosome and peroxisome
c. SER/agranilar ER
d. Free ribosome
e. Golgi complex
f. Centriole - Cytoskeleton
a. Microtubule
b. Intermediate filaments
c. Actin filaments (smallest)
Cell membrane is made up of?
lipid bilayer and glycocalyx
Regulates influx and efflux of cytoplasmic substances
Cell membrane
Spheroidal body within a cell
Nucleus
Contains gene/ DNA (deoxyribonucleic acid)
Chromosome/ chromatin granule
Contains RNA (ribonucleic acid)
Nucleolus
Porous double membrane enclosing nucleoplasm contents (nucleoplasm – fluid component of nucleus)
Nuclear envelope
Powerhouse; produces energy in the form of ATP (adenosine triphosphate), forming a total of 36 ATP per complete cycle
Mitochondrion
_____ (as suicidal bag) and _____ (both regarded as cytoplasmic vacuoles) contain _____ and _____,respectively, enzymes which bind to and destroy microorganisms and foreign agents during phagocytosis
Lysosome (suicidal bag), Peroxisome, hydrolase, oxidase
(lipid, steroid and carbohydrate syntheses)
SER/agranular ER
(protein synthesis)
RER/granular ER
Protein synthesis
Free ribosome
As packaging center; also for synthesis of large carbohydrate molecules
Golgi complex
Guides spindle fibers during mitosis and meiosis
Centrioles
Protein tubules which reinforce cell shape by holding organelles in proper position and support the whole structure
Cytoskeletons
For movement control and some aspect of mitosis
Microtubule
(smallest)
Actin filaments
Aggregate of cells with similar and coordinated functions
Tissues
Essential Components of Tissues
- Cell
- Intercelllular substance
- Junctional complex
Junctional complex (5)
a. hemidesmosome
b. desmosome
c. gap junction
d. zonula adherens
e. zonula occludens/ tight junction
Anchors cell to basement membrane
Hemidesmosome
Anchors cell to cell
Desmosome
Communicating junction
Gap junction
Adhering junction
Zonula adherens
Impemeable junction
Zonula occludens/tight junction
Fiber-secreting cells in connecting tissues
Fibroblasts
Classication of Tissues (4)
- Epithelial/Epithelium
- Connective Tissues
- Muscular Tissues
- Nervous Tissues
2 types of Epithelium
a. Simple epithelium
b. Stratified epithelium
Sheet-like tissues with a free border facing the outside environment or a body fluid
Epithelial/Epithelium
Has single layer of cells; lines body cavities, tubes and ducts (mesothelium, endothelium)
Simple epithelium
Has 2 or more layers; for protection (skin)
Stratified epithelium
Types and Distributions: (EPI)
a. Simple squamous
b. Simple cuboidal
c. Simple columnar
d. Stratified squamous
e. Pseudostratified
f. Transitional
Inner lining of blood and lymph vessels, heart, airsacs of lungs, pleura, peritoneum (mesothelium, endothelium)
Simple squamous
Ducts, secretory part of small glands, retina, kidney tubules, ovaries, testes, bronchioles
Simple cuboidal
Ducts, glands, gut, part of uterus, small bronchi
Simple columnar
Epidermis
Stratified squamous
Mid-respiratory passages (pseudostratified ciliated columnar epithelium – non keratinized)
Pseudostratified
Renal pelvis of kidney, ureter, urinary bladder, urethra
Transitional
Types of Connective Tissue Fibers (3)
a. collagen fibers
b. elastic fibers
c. reticular fibers
The most abundant and widely distributed of all tissues in complex animals; connect and support other tissues (classified according to fibroblast distribution and type of fibers present
Connective Tissues
Have collagens, which are long, flexible but not stretchable fiber
Collagen fibers
Have elastins, which are stretchable fibers (but not strong)
Elastic fibers
Have reticulins, which are similar to collagen fibers, but are thin and delicate
Reticular fibers
Types and Distributions: (CT)
a. Soft connective:
i. Loose Connective
ii. Dense Irregular
iii. Dense Regular
b. Specialized
Has fibers and fibroblast (secreting fibers) all loosely arranged in a semifluid ground substance
Loose Connective
Has fibroblasts and many collagen fibers- on skin; forms protective capsule around organs that do not stretch much
Dense Irregular
Fibroblasts occur in rows between many parallel bundles of fibers – tendon
Dense Regular
Specialized:
Adipose, cartilage (hyaline, elastic, fibrocartilage), bone, blood, hematopoietic & lymphatic tissues, (tendon, ligament), blood vessel wall, bronchial wall, trachea
(in all types of connective tissues, except _____, fibroblasts secrete fibers of structural proteins: ___,___,___)
Blood, collagen, elastin or reticulin
Tissues capable of contraction – forceful shortening of muscle fibers in response to stimulation from the outside
Muscular Tissues
Muscular Tissues contain (3)
a. Skeletal
b. Smooth
c. Cardiac
(Striated, voluntary) – muscle attached to bones
Skeletal Muscles
(Striated, involuntary) – muscle in myocardial layer of heart
Cardiac Muscles
(Non-striated, involuntary) – gastro-intestinal, bronchial, biliary, blood vessel
Smooth Muscles
(striations due to presence of _____ and _____; voluntary under _____ control; involuntary under _____ control; smooth muscle are _____; skeletal has _____; cardiac has _____ and _____)
A/ dark bands, I/ light bands
CNS, ANS
Fusiform/ spindle-shaped
Multinucleated cylindrical fibers
Branching fibers, Intercalated discs
tissues which exert the greatest control over the body’s responsiveness to changing conditions (have property of _____– ability to respond to any forms of stimuli)
Nervous Tissues
Irritability
Nervous Tissues (6)
a. Neurons
b. Neuroglia
c. Astrocytes
d. Oligodendroglia
e. Microglia
f. Schwann cells (lemocytes)
Excitable cells which form communication lines in most of the nervous system(cell body, axon, dendrite)
Neurons
Support and protect neurons structurally and metabolically(more numerous than neurons)
Neuroglia
(well-developed neuroglia) – long, star-shaped cells with numerous, highly-branched processes
Astrocytes
Small cells with scanty cytoplasm, surround nerve cells (oligodendrocyte – secretes myelin sheath in CNS)
Oligodendroglia
Phagocytic; fixed macrophage of the brain
Microglia
Secretes myelin sheath in PNS
Schwann cells (lemocytes)