Cell Flashcards
The basic structural unit of all living organisms
Cell
Give the two major components of the Cell
Nucleus and Cytoplasm
contains DNA that encodes instructions for synthesis of all proteins of cell, and the enzymes that catalyze the biochemical reactions of its metabolism
Nucleus
Thin envelope that separates the cytoplasm from the external environment
Cell Membrane
Consist of bimolecular layer of phospholipid molecules with hydrophilic heads at the outer & inner surfaces,& hydrophobic fatty acid chains directed towards the middle of the lipid blayer
Cell Membrane
the command center of the cell . Site of synthesis of ribonucleic acids
Nucleus
Usually spherical or ovoid in shape located near the center of the cell
Nucleus
N….contains DNA that encodes instructions for synthesis of all proteins of cell, and the enzymes that catalyze the biochemical reactions of its metabolism
Nucleus
4 parts of Nucleus
Chromatin
Nucleolus
Nuclear lamina
Nuclear envelope
- clumps of conspicuous intensely basophilic material in the nucleus. Consist of DNA and associated proteins in CONDENSED state
Chromatin
- is visible in the living cell as a sperical refractile body located eccentrically in the nucleus.
Its function is to rewrite rRNA and combine it with proteins (VITAL ROLE IN MAKING PROTEINS IN THE CELL)
Nucleolus
– it serve as boundary of nucleus consisting of 2 parallel membranes.
Serves as communication between the nucleoplasm and cytoplasm
Nuclear envelope
•Is the region of the cell between the plasma membrane and the nuclear envelope
Cytoplasm
Contains cell organelles (mitochondria, endoplasmic reticulum, Golgi complex, lysosomes and peroxisomes) and inclusions suspended in a semi- fluid cytosol
Cytoplasm
- are slender sausage- shaped structures and exhibits some variations in shape in different cell types
•Found to have 2 membranes
MITOCHONDRIA
Most numerous in high energy requiring cells such as muscle & neurons
•GENERATE the chemical ENERGY necessary for most of the biochemical reactions that take place in the cytoplasm
MITOCHONDRIA
Largest of the cytoplasmic organelle
Endoplasmic Reticulum
- studded with ribosomes. Related to protein synthesis
Rough endoplasmic reticulum
- involve in synthesis of cholesterol and steroid hormones.
Smooth endoplasmic reticulum
Abundant in interstitial cells of testis (secreting testosterone).
Smooth endoplasmic reticulum
In liver it function in detoxification of drugs and alcohol & participate in synthesis of glycogen
Smooth endoplasmic reticulum
it is where the newly synthesized proteins, received from the rER, are further processed, SORTED,and PACKAGED for transport to their final destinations in the cell.
Golgi Complex
Largest in secretory cell types
Golgi Complex
- contain more than 30 hydrolytic enzymes that have acid pH
“Digestive system”of the cell decomposing substances taken into the cell and disposing of excess, or damaged, cell organelles
Lysosomes
-bear some RESEMBLANCE to LYSOSOMES, but they are more consistently spherical and less dense
•Participate in a number of important biochemical pathways.
Peroxisomes
Their oxidative reactions breakdown amino acids,uric acid, & fatty acids
Perixisomes
consists of 2 centrioles in the center of a sphere of material of low density , described as pericentriolar matrix.
Centrosome
In non dividing cells, it nucleate the polymerization of long, single,microtubules that radiate throughout the cytoplasm. This contribute to maintenance of cell shape & serve as tracks along which transport vesicles and organelles from place to place by motor proteins
Centrosome
In dividing cells they nucleate the polymerization of the microtubules of the mitotic spindle
Centrosome
-it is metabolized by cells to enable them to SYNTHESIS ATP, w/c provides the energy for most of the biochemical reactions taking place in the cell
Glycogen
- multiple small lipid droplets containing cholesterol esters, as well as triglycerides, are mostly seen in cells specialized for steroid hormones
Lipid
- They have no metabolic value, but the cell seems to have no way of eliminating them
Lipofuchsin pigment
-determines cell shape & many of the physical properties of the cytoplasm
•It is very dynamic
Cytoskeleton
•Three categories of filaments:
- 1.Microfilaments(actin and myosin filaments)
- 2.Intermediate filaments
- 3.Mictrotubules
-contractile activity in muscle cells primarily results from the interaction of 2 protein namely actin(thin) & myosin(thick) filaments
Microfilaments
- cell contain a class of intermediate-sized filaments with an average diameter of 10-12nm. Example of this are cytokeratins(epithelium),vimentin(mesenchymall cells),desmin(muscle), glial fibrillary acidic protein(glial cells), neurofilaments(neurons)
Intermediate filaments
play a significant role in the development and maintenance of cell form
Microtubules
They are also implicated in the intracellular transport of other organelles
Microtubules
They are also implicated in the intracellular transport of other organelles
Microtubules
- are continuous sheets closely adherent cells(epithelia) that line portions of the respiratory and reproductive tracts, that are motile cell processes
ung parang micro hairs
Cilia
-are single propellant , with several times the length of cilia.
Flagellum
is the only cell in mammal that demonstrate such structure
Spermatozoon
- taking of extracellular materials into the cells in invaginations of the cell membrane that pinch off to form vesicles which move in the cytoplasm
Endocytosis
- non-selective form of endocytosis in which small and large molecules in solution are taken up in the concentration of extracellular fluid
Pinocytosis
mechanism for the selective concentration and uptake of specific protein molecules from the extracellular fluid
Receptor-mediated endocytosis
-internalization of particles, such as bacteria , for destruction within the cell
Phagocytosis
-structural units of the genetic material of Chromosomes-structural units of the genetic material of the cell, each consisting of a linear double-stranded DNA molecule and associated proteins cell, each consisting of a linear double-stranded DNA molecule and associated proteins
Chromosomes
ordered sequence of events that a cell undergoes from its origin to its division
Cell Cycle
- period between the origination of the cell and its division. Occupies 95% of the cycle
Interphase
- division into two daughter cells, occupies only few hours
Mitosis
Five stages of mitosis
- Prophase
- Prometaphase
- Metaphase
- Anaphase
- Telophase
- a cell division that occurs only in the production of the ova and spermatozoa
•The chromosome number must be reduced by half to prevent a doubling of the chromosome number at fertilization
Meiosis
- or programmed cell death
•This is an active, energy-dependent, gene-directed process, a kind of cell suicide
Apoptosis
not a programmed process of cell death
•Result fom anoxia, mechanical injury,invasion of cell by viruses,exposure to toxins,or to irradiation
Necrosis