Celiac Disease

Question 1

What is celiac disease

Answer 1

Chronic inflammatory disease primarily affecting small intestine

Question 2

Celiac disease results from

Answer 2

Inflammatory response initiated by dietary gluten

Question 3

Inflammation leads to

Answer 3

damage and atrophy of the intestinal villae

Question 4

Celiac disease is associated with _______ and risk of developing _________

Answer 4

Nutrient malabsorption, micronutrient and macronutrient deficiencies

Question 5

Loss of intestinal structure is caused from

Answer 5

villi and microvilli damaged in celiac disease autoimmune response

Question 6

How does celiac disease cause increased risk of developing intestinal cancer

Answer 6

Constant cycles of cell division and attempts to repair intestinal epithelial cell damage

Question 7

Latent celiac disease

Answer 7

-patients with the potential to develop clinical symptoms
-no mucosal lesion
-normal instestinal villi

Question 8

Silent celiac disease

Answer 8

Damaged intestinal villi

Question 9

Is protein digestion (enzyme function) and amino acid absorption in people with celiac disease normal or not normal?

Answer 9

Normal

Question 10

Gluten proteins and enzymatic digesion

Answer 10

Gluten proteins are resistant to enzymatic digestion in everyone

Question 11

Problems in people with CD and result

Answer 11

CD patients the immune response against gluten results in damage to the
small intestine epithelial barrier, laminal propria, and intestine tissue structure
→ LOSS OF VILLI
→open lesions/ wounds
/ulcerations in the small intestine
RESULT: secondary complications for nutrient absorption and risk of infection