CDs Flashcards
1
Q
CD3
A
T cells
2
Q
CD4
A
helper T cell
3
Q
CD8
A
cytotoxic T cell
4
Q
CD13
A
monocytes, granulocytes
5
Q
CD14
A
monocytes
6
Q
CD15
A
granulocytes, monocytes
7
Q
B Cell CDs
A
CD19, CD20, CD22
8
Q
CD34
A
blasts/stem cells
9
Q
CD45
A
leukocytes
10
Q
immature markers (5)
A
TDT (see in ALL) CD34 (see in AML and ALL) CD10 CD117 (see in AML) CD1a
11
Q
immunophenotype of B-ALL
A
CD34, CD10, TDT, CD19 CD20(-)
12
Q
immunophenotype of T-ALL
A
CD3, CD4-8duality, TDT
- must differentiate from B-ALL bc may present morphologically identical
- -> do Flow Cytometry (CD3, CD1a)
13
Q
Immunophenotype CLL
A
CD5, CD19, CD23
14
Q
Good prognostic factors CLL
A
deletion 13q
mutated IgHV
low Rai stage
15
Q
Bad prognostic factors CLL
A
deletion 11q or 17q (gene for p53)
unmuted IgHV
high Rai stage
CD38/ZAP-70 expression
16
Q
immunophenotype Hairy Cell Leukemia
A
CD19, CD20, CD11c, CD22
TRAP pos
17
Q
CD10
A
germinal cell marker
pos in Burkitt lymphoma and Follicular lymphoma
18
Q
CD15, CD30 pos
A
Classical Hodgkins Lymphoma
19
Q
CD20, CD45 pos
A
Nodular lymphocyte predominate hodgkin lymphoma
