CD markerek Flashcards

1
Q

CD4

A
Helper T (+ Treg)
MHC-II kötés
Citokintermelés
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2
Q

CD8

A

Citotoxikus T, gammadeltaT

MHC-I kötés

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3
Q

CD 80

A

B7-1

APC sejt felszínén

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4
Q

CD 28

A

T sejt aktivacio kostimulacios molekulája (T sejt felszínén)
IL-2 és IL-2-R expressziojat indukalja
T sejt proliferaciot indukalja

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5
Q

CD 86

A

B7-2

APC sejt felszínén

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6
Q

CD 152

A

CTLA4 T sejten

B7hez köt

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7
Q

CD 45

A

C típusú PTPRC
Nagy fokban glikozilalt
T sejt regulacios szerep (TPáz domen defoszforilalodik)

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8
Q

CD 45ABC

CD 45RA

A

ABC szakasz alternativan kivagodo exonok

Nyugvó sejteken, naiv T sejteken

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9
Q

CD 45RO

A

Kisebb molekulasuly

Aktivált T sejteken, limfocitakon, memória sejteken

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10
Q

CD 44

A

Aktivált és memória T/B sejteken, makrofagokon, finroblastokon, idegsejteket
Szerep: recirkulacio

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11
Q

CD 25

A

IL2R

T sejt aktivacio

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12
Q

CD 154

A

CD40L

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13
Q

CD 59

A

MAC inhibitor

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14
Q

CD 3

A

TCR része -> minden T sejten (sejtvonal marker)

-CD3 KOMPLEX-

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15
Q

CD 19

A

Minden B sejten

Sejtvonal marker

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16
Q

CD 20

A
B sejt érési marker:
CLP -
ProB -
PreB +
Éretlen B +
Érett B +
Plazmasejt -
17
Q

CD 23

A

IgE receptor = FcER2
Alacsony aff.
Szolubilisan is