CCU Flashcards

1
Q

What is normal cardiac output?

A

5 L per min

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2
Q

What is the equation for cardiac output?

A

CO = SV x HR

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3
Q

What is the equation for blood pressure?

A

BP = CO x TPR

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4
Q

What is meant by the pulse pressure?

A

The difference between the systolic and diastolic pressure. It represents the force the heart produces each time it contracts.

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5
Q

What is compliance and what is its relevance to hypertension?

A

Complications = volume/pressure . Normally, increased transmural pressure dilated a vessel, reducing resistance. If there is reduced compliance, the change in volume reduces so pressure is not reduced as much. Essentially, the vessels are stiff.

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6
Q

How do you calculate the rate from an ECG?

A

Regular rhythm: 300 / no. of large squares between each R wave.
Very fast rhythm: 1500 / no. of small squares between each R wave.
Irregular or slow rhythm: number of complexes on rhythm strip x 6

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7
Q

What is the main causative organism of infective endocarditis?

A

Streptococcus viridans

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8
Q

What is a key symptom that would cause you to suspect infective endocarditis?

A

Tiredness

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9
Q

What is the causative organism of rheumatic fever?

A

Lancefield group A beta-haemolytic streptococci.

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10
Q

Why can rheumatic fever damage the heart valves?

A

Antibody to the streptococcus cross-reacts with valve tissue (antigenic mimicry) and may cause permanent damage to the valves.

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11
Q

What are the causes of mitral stenosis?

A

Rheumatic fever, congenital, infective endocarditis, mucopolysaccharidoses, prosthetic valve, cardial fibroelastosis, malignant carcinoid

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12
Q

What condition are patients with mitral stenosis at risk of developing?

A

Atrial fibrillation

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13
Q

What are patients with AF at risk of developing?

A

Thrombi that embolize to peripheral circulation

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14
Q

What is a sign on the face of mitral stenosis?

A

Malar flush (due to CO2 vasodilation)

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15
Q

How is infective endocarditis diagnosed?

A

Duke criteria - positive “serial blood cultures” and echocardiogram plus 5 minor criteria.
Definite endocarditis: 2 major or 1 major and 3 minor or all 5 minor criteria .

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16
Q

What is the blind antibiotic therapy for infective endocarditis?

A

Amoxicillin and gentamicin IV (native valve)
Use vancomycin instead of amoxicillin if allergic.
Vancomycin, gentamicin and rifampicin (prosthetic valve)

17
Q

Are the antibiotics given for staph. aureus caused infective endocarditis different to those given for strep. Viridans?

A

Yes, staphs are treated with flucloxacillin (vancomycin if allergic) and streps are treated with benzylpenicillin

18
Q

Give some examples of drugs that cause bradycardia

A

Beta-blockers, digoxin, diltiazem, verapamil