CC Pharm

Question 1

A graph depicting the rise and fall of an inhaled anesthetic agent in different areas of the body is shown. Drag the name to the corresponding letter.

Answer 1

A. Alveoli
B. Brain
C. Muscle
D. Fat

Question 2

Label the corresponding Volatile to its chemical structure.

Answer 2

1. Des
2. Nitrous
3. Sevo
4. Iso

Question 3

Put the definition with the word.

A. A drug that binds to the receptor, resulting in opposite action of the antagonist

B. A drug that binds to a specific receptor and triggers a response

C. Drug that has an affinity for a receptor but no efficacy

D. Drug that activates a receptor but cannot produce maximal reponse

Answer 3

A. Inverse agonist
B. Agonist
C. Antagonist
D. Partial Agonist

Question 4

A patient undergoing debridment of wounds under hyperbaric conditions. If the pressure in the chamber is two atmospheres, the MAC of des would be _____?

Answer 4

Answer: 3%

The MAC of des at 1ATM is 6% of 760 mmHg = 45.6 mmHg

MAC of Des at 2ATM =29.392 PSI 45.6 / 1520 = 0.03 or 3%

Question 5

A low dose epi infusion would be expected to produce:

Answer 5

Increased perfusion of skeletal muscle.

Few alpha effects are seen and beta effects predominate

Question 6

A 23M is undergoing thoracotomy for resection of blebs. He currently has a 500 mL pneumothorax present. If the patient is anesthetized with an anesthetic of Dec with nitrous and oxygen in a 2:1 ratio, the resultant volume of the pneumothorax will approach:

Answer 6

Answer 1500 mL

A compliant airspace, such as
a pneumothorax, will increase
in volume during nitrous
oxide administration.
Theoretically, at 50% inspired
nitrous oxide, the gas bubble
would double in volume.
Similarly, at 67% nitrous
oxide could triple the volume.

Question 7

As compared to a 40 year old adult, the required MAC of a 6month old infant is approximately:

Answer 7

Answer: 1.5 - 1.8x higher

The MAC or required dose of
anesthetics is higher in infants
and children and decreases
with increasing age. Infants
aged 6 months have a MAC
1.5 to 1.8 times higher than a
40-year-old adult. The MAC
of inhalational agents is
decreased by 4% per decade
of age over 40 years.The
MAC or required dose of
anesthetics is higher in infants
and children and decreases
with increasing age. Infants
aged 6 months have a MAC
1.5 to 1.8 times higher than a
40-year-old adult. The MAC
of inhalational agents is
decreased by 4% per decade
of age over 40 years.

Question 8

Actions produced by the opiate agonist action on the receptor include:

Answer 8

Analgesia
Inhibition of ADH release
Antishivering effect

Question 9

Awakening after an induction dose of propofol is due to:

Answer 9

Redistribution of the drug to the peripheral compartment

Rapid distribution following
an induction dose of propofol
into the brain results in fast
onset of generally one
circulation time. Rapid
redistribution from the central
compartment to the peripheral
compartments produces a
quick initial decline.
Metabolism plays little role in
the initial awakening of the
patient.