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CC PROTEINS > CC GNE > Flashcards

CC GNE Flashcards

1
Q

ultimate end product of protein

A

AMINO ACID

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2
Q

Basic structure of an amino acid

A

amino group
R group
carboxyl group
hydrogen
carbon- central part

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3
Q

enzymes that are responsible for digestion of protein

A

pepsin
trypsin

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4
Q

What is DEAMINATIOM
enzyme for deaminatiom
where do deamination happens

A

Deamination is the removal of amino group
DEAMINASE
kidneys and liver

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5
Q

WHAT IS TRANSAMINATION

A

removal of amino group but will be transferred to a keto acid

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6
Q

these are amino acids that can be converted into glucose

A

glucogenic amino acid

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7
Q

examples of glucogenic AA and its deaminated form

A

alanine- pyrivate
arginine- a ketoglutarate
aspartate- oxaloacetate

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8
Q

amino acids that generates ketone bodies

A

ketogenic AA

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9
Q

what do ketone bodies degrade

A

acetyl-coA

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10
Q

example of ketogenic AA

A

leucine
lysine

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11
Q

differentiate essential AA from non-essential AA

A

essential- come from food
non-essential- naturally made by body

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12
Q

NAME THE ESSENTIAL AMINO ACIDS

A

PVTTIMHALL

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13
Q

fasting for AA

A

6-8 hrs

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14
Q

best anticoag for plasma (AA)

A

Heparin

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15
Q

AA- if analysis cannot be done store in

A

-20- x- 40

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16
Q

Urine is used to (quantify/qualify) level of amino acids?

sample should be collected for

preservative

A

quantify

24 hrs

thymol

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17
Q

what happens when WBCs are elevated

A

affects AA determination (aspartic, glitamic)

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18
Q

absence of phenylalanine hydroxylase

A

PHENYLKETONURIA

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19
Q

what do PAH convert

A

phenylalanine to tyrosine

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20
Q

a drug used to manage PKI

A

Kuvan

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21
Q

semi quantitaive test to determine level of phenylalanine

A

Guthrie

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22
Q

used to quantify conc of phenylalanine

A

HPLC

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23
Q

inhibits break down of tyrosine

A

tyrosinemia

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24
Q

metabolite of tyrosine

A

succinylacetone

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25
Q

Patient has microcephaly and has musty odor urine

A

Phenylketonuria

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26
Q

Most severe.
Urine is cabbage like
Low levels of Fumarylacetoacetate Hydrolase

A

Type 1 Tyrosinemia

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27
Q

deficiency in tyrosine aminotransferase

A

Type 2 Tyrosinemia

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28
Q

Most rare.
Mainly found in liver

A

Type 3 Tyrosinemia

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29
Q

Urine turns brownish black when exposed to air

A

Alkaptonuria

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30
Q

absence of a-ketoacid dehydrogenase

31
Q

burnt sugar odor in urine,breathe and skin

32
Q

sweaty feet urine odor

A

ISOVALERIC ANEMIA

33
Q

enzyme required for breaking down of branced AA

A

a-ketoacid dehydrogenase

34
Q

enzyme involved in the conversion of methionine to cysteine

35
Q

elevated levels of methionine and cysteine in blood and urine

cross eyed

A

Homocystinuria

36
Q

most common form of citrullinemia
ASS deficiency

37
Q

baby won’t breastfeed
baby vomits
seizure

A

type 1 citrullinemia

38
Q

rare type of citrullinemia
japanese people

39
Q

defect in the AA transport system
formation of kidney stones

A

cystinuria

40
Q

small precursors to large molecules

A

anabolic pathway

41
Q

3 STAGES OF CATABOLIC PATHWAY

A

DIGESTION
ENERGY RELEASE
ENERGY STORAGE

42
Q

hormones that promote building up of larger molecules

A

anabolic hormone

43
Q

higher intake, lower elimination

A

positive nitrogen balance

44
Q

lower intake, higher elimination

A

negative nitrogen balance

45
Q

Where do digestion starts

46
Q

summary of protein digestion

A

stomach -pancreas- small intestine- liver

47
Q

what will be the net charge if the ph is greater than isoelectric point

if the ph is lower than ip

A

greater- negative
lesser- positive

48
Q

level of protein on edematous people

49
Q

2 plasma proteins

A

albumin
globulin

50
Q

long term monitoring of glucose

51
Q

ascending concentration of major plasma protein

A

pre al
albumin
a1
a2
hapto
transferrin

52
Q

storage of oxygen

53
Q

cardiac marker

54
Q

myoglobin increase on AMI within ____ onset and reaches peak level in ______ hours

55
Q

gold standard for acute coronary syndrome

A

Cardiac troponin

56
Q

level of cTnT that can kndicate myocardial damage

57
Q

adhesive glycoproteins

A

fibronectin

58
Q

used to predict short term risk of premature delivery

A

fetal fibronectin

59
Q

accurate marker of CSF leakage

A

b-trance protein

60
Q

marker for bone resorption

A

cross linked C-telopeptide

61
Q

marker for GFR

A

cystatin C

62
Q

differentiates alzheimers from diff forms of dementia

63
Q

test for urine proteins

64
Q

positive result for urine proteins

A

precipitate

65
Q

reference range for urinary protein

A

10-250 mg/24 hrs

66
Q

reference values for CSF protein

A

15-45 mg/dL

67
Q

csf albumin serum albumin ratio

68
Q

Patient has CSF protein of 10 mg/dL. What possible conditions are associated

A

hyperthyroidism

69
Q

test used in total nitrogen analysis

A

chemiluminescence

70
Q

in salt fractionation, what is the supernatant

71
Q

reference for total protein in ambulatory and recumbent

A

6.5-8.3

6.0-7.8

72
Q

test to quantify CHON

73
Q

widely used for protein analysis

74
Q

presence of 2 polypeptide in biuret method give what color

A

violet colored chelate

CC PROTEINS (1 decks)

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