Causation, Drugs and Depression

Question 1

What is causal behaviour? What is causal power?

Answer 1

Lecture 6, slide 2

Question 2

How did a study by Blaisdell et al. (2006) suggest that rats have causal knowledge? What is the issue with the study?

Answer 2

Lecture 6, slide 7, 10

-11

Question 3

How is a food reward related to DA release? What is conditioned place preference?

Answer 3

Lecture 6, slide 16-17

Question 4

What effects do drugs have on dopamine release? What does the study by Hemby et al (1997) show?

Answer 4

Lecture 6, slide 18-20

-study shows that: dopamine release is influenced by the nature of the behavioural association that is formed

Question 5

What study did Calipari et al. (2017) conduct to determine the effect of oestrogen on cocaine-dependent learning?

Answer 5

Lecture 6, slide 20-23
-women in their menstrual cycle have a stronger CPP compared to men and women not on their periods (maybe because they have a greater DA response to the drug).

Question 6

Why do women on their menstrual cycles experience increased cocaine CPP compared to men and women not on their period?

Answer 6

Lecture 6, slide 24

Question 7

What are the major theories of compulsive drug use?

Answer 7

Lecture 6, slide 25

Question 8

What role does DA have in drug seeking/craving?

Answer 8

Lecture 6, slide 26

Question 9

What is the Skinnerian chaining procedure? What is behavioural sensitization? What is neurochemical sensitization?

Answer 9

Lecture 6, slide 27-28

Question 10

What are some non-pharmacological determinants of drug action?

Answer 10

Lecture 6, slide 29

Question 11

What do the Rat Park experiments show? How specific are drug-environment interaction?

Answer 11

Lecture 6, slide 30-32

-drug-environment interactions are substance-specific

Question 12

What behavioural marker is there for nausea in rats? What brain systems seem to be involved in regulating naseau?

Answer 12

Lecture 6, slide 33, 35

Question 13

What effect does does depletion of forebrain serotonin have on nauseau? What are some studies that show this?

Answer 13

Lecture 6, slide 36-38

Question 14

What is the neurobiology of nausea in the IIC?

Answer 14

Lecture 6, slide 39

Question 15

What are some rodent models of depression? What is affective bias?

Answer 15

Lecture 6, slide 40

Question 16

What is negative bias? Give a study that illustrates negative bias.

Answer 16

Lecture 6, slide 41

Question 17

What effect do antidepressants have one affective bias?

Answer 17

Lecture 6, slide 42-43

-they induce positive affective biases

Question 18

What effect does depression have on helplessness judgements? How do SSRIs affect this?

Answer 18

Lecture 6, slide 44-49, 52-54

Question 19

What effects do SSRIs have on 5-HT synapses?

Answer 19

Lecture 6, slide 50