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Pharm > Catecholamines > Flashcards

Catecholamines Flashcards

1
Q

T/F catecholamines pass the blood brain barrier very poorly.

A

True

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2
Q

Describe the epinephrine.

A

Direct acting
Catecholamine
Adrenergic agonist

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3
Q

Describe NE

A

Direct acting
Catecholamine
Works on a1,a2 and b adrenergic receptors

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4
Q

Describe isoproterenol.

A

Direct acting

Catecholamine

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5
Q

Describe dopamine.

A

Precursor to NE.

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6
Q

Describe GABA.

A

Inhibitory neurotransmitter

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7
Q

Describe glutamate and aspartate

A

CNS amino acids

Excitatory effects on cns

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8
Q

List the catecholamines.

A

Epi, NE, isoproterenol, dopamine, dobutamine.

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9
Q

What sympathomimetic has clinical applications for anaphylaxis, glaucoma, asthma and vasoconstriction?

A

Epi

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10
Q

What sympathomimetic causes vasoconstriction during HYPOtension?

A

NE

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11
Q

What is the clinical application of isoproterenol?

A

Asthma

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12
Q

Dopamine and dobutamine have clinical application for what emergencies?

A

Shock and hear failure

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13
Q

Amphetamine, phenmetrazine are used to treat?

A

Narcolepsy, obesity and ADHD.

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14
Q

Ephedrine is used to treat?

A

Incontinence an vasoconstriction during HYPOtension.

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15
Q

Phenylephrine causes?

A

Mydrasis, vasoconstriction, decongestion.

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16
Q

Analeptics are cns stimulants that treat?

A

Drug induced respiratory depression and hypnosis.

17
Q

What is the action of xanthines?

A

Improve mental alertness, reduce the urge to sleep and elevate mood.

18
Q

Theophylline is what type of stimulant and what is it used to treat?

A

Xanthine, used to treat asthma.

19
Q

What is considered the toxic range for caffeine?

A

> 1000mg a day

20
Q

What part of the cns does caffeine stimulate the most?

A

Cortex

21
Q

Liberation of ach after threshold stimulus does what to the cell?

A

Alters cell membrane permeability.

Pharm (2 decks)

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