cataracts Flashcards
def cataracts
opacification of the lens of the eye
aetiology cataratcs
age - Majority of cases are idiopathic age-related (‘senile cataracts’).
in children many are genetic (?genetic in adult too)
systemic secondary causes
congenital secondary causes - congenital rubella syndrome
high myopia
smoking
alcohol excess
sunlight exposure
HIV +ve
local secondary causes
- previous eye trauma
- uveitis
- intraocular tumours
systemic secondary causes of cataracts
dm - when cataract is found measure fasting plasma glucose
metabolic disorders (galactosaemia, hypocalcaemia, Wilson’s disease)
steroid use
dystrophia myotonica
skin disease (atopic dermatitis, scleroderma)
genetic syndromes - down’s
radiotherapy
path cataracts
seen with slit lamp microscope
in early stages - compression of lens fibre in central portion of the lens (nuclear sclerosis)
gradual change of the crystaline lens nucleus from translucent to brown/grey
There may be areas of granular opacities (e.g. in posterior subcapsular sub-type).
epi cataracts
Major cause of treatable blindness worldwide.
Cataracts are found in 75% of >65s but in only 20% of 45–65-year-olds
sx cataracts
blurred vision
Unilateral cataracts are often unnoticed, but loss of stereopsis affects distance judgement
Bilateral cataracts cause gradual painless loss of vision (frequent spectacle changes as refraction changes) ± dazzle (esp. in sunlight) ± monocular diplopia
difficulties driving at night and haloes around street lights.
Glare from bright light, vision may worsen in bright light (especially with central lens opacity).
Some may notice that they can read without glasses (nuclear sclerotic cataractmay”lens-converging power).
children - squint, nystagmus, amblyopia (lazy eye)
signs cataracts
loss of red reflex, hazy lens appearance
reduced visual acuity
opthalmoscopic classification is by lense appearance:
- immature catacracts - red reflex still present
- in dense cataracts - no red reflex or visible fundus
- nuclear cataracts
- change the lens refractive index, dull colours - common in old age
- cortical cataracts
- spoke like wedge opacities
- milder effect on vision
- posterior sub-capsular cataracts
- progress faster
- cause classic glare from bright lights - even when acuity is only mildly affected
- Subcapsular opacities (eg from steroid use) are just deep to the lens capsule—in the visual axis.
- Dot opacities are common in normal lenses but are also seen in fast-developing cataracts in diabetes or dystrophia myotonica.
ix cataracts
Unnecessary unless occuring at an early age or in background of systemic disease.