CaseFiles Flashcards
1
Q
stages of sleep
A
NREM
- stage 1: theta - high freq, low voltage (like REM)
- stage 2: K complexes and sleep spindles
- stages 3 and 4: delta waves - low freq, high voltage - night terrors
REM: high freq, low voltage - nightmares
2
Q
Mild intellectual disability:
- criteria
- what is Vineland Social Maturity Scale
- 3 common etiologies
- mild
- moderate
- severe
- profound
- aggressive behavior in moderate/severe could indicate?
- most common cause
A
- intelligence deficit + adaptive functioning deficits + onset during development
- adaptive functioning test
- down, fragile x, PKU
- school age, gullible, can hold jobs
- before school, limited jobs
- spoken language limited, need help for daily living
- nonverbal
- pain
- idiopathic
3
Q
Autistic spectrum
- features
- 2 specific disorders
- MRI findings
- vs. intellectual disability
- vs. childhood schizophrenia
- tx
- meds for irritation
A
- poor social and language skills + repetitive and odd play; can have islets of precocity
- Asperger = social impairment only; Rett = regression 2/2 unknown etiology, girls only
- increased cortical thickness / total brain vol
- repetitive activity, poor social skills
- younger age of manifestation
- multi-systemic therapy, oxytocin
- aripiprazole
4
Q
ADHD
- subtypes
- criteria
- tx
- toxic cause
A
- hyperactive/impulsive vs. inattentive vs. combined
- > 6 sx for >6mo in 1 setting: inattentive, hyperactive, impulsive
- behavior modification + amphetamines or atomoxetine if h/o substance abuse, tics, anxiety -> clonidine or guanfacine -> bupropion and imipramine (QTc)
- Pb intoxication
5
Q
Tourette
- genetics
- associated w which 2 diseases
- criteria
- athetoid vs. choreiform -> ddx?
- tx
A
- ?AD
- OCD and ADHD
- multiple motor + >1 vocal tics for >1yr w onset Huntington, Wilson’s, tardive dyskinesia
- psychotherapy, clonidine, guanfacine -> risperidone
6
Q
PANDAS
- what is it
- conditions
A
- strep infection
2. OCD/tics
7
Q
Mech
- clonidine
- guanfacine
- atomoxetine
A
- a-adrenergic agonist presynaptic -> decreases NE pathway
- a-adrenergic agonist post synaptic -> decreases NE activity
- a-adrenergic agonist presynaptic -> decreases NE released
8
Q
schizoaffective
- subtypes
- criteria
- MRI
- tx
A
- depressive vs. bipolar
- psychosis +/- mood (no mood for >2wks)
- white matter pathology
- depressive: antipsychotic -> +antidepressant only if mood sx remain; bipolar: antipsychotic + Li/carbamazepine/valproate
9
Q
Schizophrenia
- criteria
- catatonia
- 6mo
- tx
A
- > 6mo of +/- sx, >2 sx of psychosis for >1mo
- > 3 psychomotor sx
- brief psychotic vs. schizophreniform vs. schizophrenia
- atypical antipsychotics
10
Q
hallucinations vs. hallucinosis
A
no insight vs. yes insight
11
Q
only antipsychotic w anti-suicidal properties
A
clozapine
12
Q
Medical psychosis
- vs. primary psychotic disorder
- meds causing psychosis
- tx
A
- older age onset, can be visual/olfactory/gustatory hallucinations
- antihypertensives, antimicrobials, anticholinergics, corticosteroids, antineoplastics
- underlying medical condition; can add antipsychotics for sx relief
13
Q
Bipolar
- 2 types
- rapid cycling
- criteria
- typical feature of mania in adolescents
- tx
A
- I - mania >1wk; II - hypomania + depression >2wks
- 4 episodes in 1 yr
- > 3 sx
- psychosis
- psychotherapy + mood stabilizer (Li; valproate for younger kids)
14
Q
Cyclothymic
- criteria
- tx
A
- > 2yrs of constant hypomania depression w/o meeting criteria for hypomania, mania , MDD criteria. NO psychosis.
- mood stabilizers
15
Q
Depression from hypothyroidism
- physical signs
- tx
A
- weight gain, coarse brittle hair
2. levothyroxine