Case Files O&G Flashcards

1
Q

A 48-year-old G3 P3 woman complains of a 2-year history of loss of urine four to five times each day, typically occurring with coughing, sneezing, or lifting; she denies dysuria or the urge to void during these episodes. These events cause her embarrassment and interfere with her daily activities. The patient is otherwise in good health. A urine culture performed 1 month previously was negative. On examination, she is slightly obese. Her blood pressure is 130/80 mm Hg, her heart rate is 80 beats per minute, and her temperature 99°F (37.2°C). The breast examination is normal without masses. Her heart has a regular rate and rhythm without murmurs. The abdominal examination reveals no masses or tenderness. A midstream voided urinalysis is unremarkable.

  • What is the most likely diagnosis?
  • What physical examination finding is most likely to be present?
  • What is the best initial treatment?
A

Genuine stress urinary incontinence

Hypermobile urethra, cystocele, or loss of
urethrovesical angle.

Kegel exercises and timed voiding.

Case 1

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2
Q

A 55-year-old woman notes constant wetness from her vagina following a total vaginal hysterectomy procedure, which she had undergone 2 months previously. She denies dysuria or urgency to void. The urinanalysis is normal. What is the best method to diagnose the etiology of urinary incontinence?

A

Dye instillation into bladder

Case 1

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3
Q

A 42-year-old woman with long-standing diabetes mellitus complains of small amounts of constant dribbling of urine loss with coughing or lifting.

What is the most likely diagnosis?
What is the best therapy?

A
  • Overflow Urinary Incontinence (Neurogenic Bladder)
  • Intermittent self-catheterization

Case 1

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4
Q

A 39-year-old woman wets her underpants two to three times each day. She feels as though she needs to void, but cannot make it to the restroom in time.

What is the most likely diagnosis?
What is the best therapy?

A
  • Urge Urinary Incontinence
  • Oxybutynin (Ditropan, an anticholinergic medication relax overactive detrusor muscle

Case 1

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5
Q

A 35-year-old woman has undergone four vaginal deliveries. She notes urinary loss six to seven times a day concurrently with coughing or sneezing. She denies dysuria or an urge to void. Her urine culture is negative.

What is the most likely diagnosis?
What is the initial therapy?

A
  • Stress urinary incontinence
  • Kegel exercises (pelvic floor strengthening)
  • urethropexy if Kegel exercises fail
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6
Q

After a 4-hour labor, a 31-year-old G4 P3 woman undergoes an uneventful vaginal delivery of a 7 lb 8 oz infant over an intact perineum. During her labor, she is noted to have mild variable decelerations and accelerations that increase 20 beats per minute (bpm) above the baseline heart rate. At delivery, the male baby has Apgar scores of 8 at 1 minute, and 9 at 5 minute. Slight lengthening of the cord occurs after 28 minute along with a small gush of blood per vagina. As the placenta is being delivered, a shaggy, reddish, bulging mass is noted at the introitus around the placenta.

  • What is the most likely diagnosis?
  • What is the most likely complication to occur in this patient?
A

Most likely diagnosis: Uterine inversion.

Most likely complication: Postpartum hemorrhage

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7
Q

List the FOUR signs of placental separation

A
  1. Gush of blood
  2. Lengthening of the cord
  3. Globular-shaped uterus
  4. Uterus rising to the anterior abdominal wall
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8
Q

What is the most common complication of inverted uterus

A

Hemorrhage

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9
Q

What should you do when the placenta does not deliver spontaneously after 30 minute?

A

Attempt manual extraction

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10
Q

A 49-year-old woman complains of irregular menses over the past 6 months, feelings of inadequacy, vaginal dryness, difficulty sleeping, and episodes of warmth and sweating at night. On examination, her blood pressure is 120/68 mm Hg, heart rate is 90 beats per minute, and temperature is 99°F (37.2°C). Her thyroid gland is normal to palpation. The cardiac and lung examinations are unremarkable. The breasts are symmetric, without masses or discharge. Examination of the external genitalia does not reveal any masses.

  • What is the most likely diagnosis?
  • What is your next diagnostic step?
A

-Perimenopausal state
-Serum follicle-stimulating hormone (FSH) and
luteinizing hormone (LH)

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11
Q

What is the indication for hormone replacement therapy in the menopausal woman?

A

Significant vasomotor symptoms (night sweats, hot flashes, and flushes)
-Use the lowest dose for the shortest duration feasible

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12
Q

How would you counsel women to prevent osteoporosis?

A
  • Weight-bearing exercise
  • Calcium
  • Vitamin D supplementation
  • Estrogen replacement therapy with progesterone if uterus present to prevent endometrial cancer
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13
Q

The Women’s Health Initiative Study raised concerns about the risks regarding continuous estrogen-progestin treatment. What were they? List TWO

A

Small but significant increase risk of:

  • Breast Cancer
  • Heart disease
  • Pulmonary embolism
  • Stroke
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14
Q

The Women’s Health Initiative Study found benefits of women on hormone replacement therapy. List two benefits

A
  • Fewer Fractures

- Lower incidence of colon cancer

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15
Q

You have a patient in septic shock. How would you manage this patient

A
  • ABC’s
  • Oxygen
  • Monitors-perfusion and organ function (BP cuff, Pulse Ox, ECG leads)
  • Intravenous fluids
  • Source control-removing cause of infection
  • Intravenous broadspectrum antibiotics
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16
Q

What organism is most typically responsible for causing a sunburn-like rash and/or desquamation infections?

A

Staphylococcus aureus

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17
Q

Despite intravenous isotonic fluid replacement, your patient remains hypotensive. What is your next step?

A

Vasopressor support such as intravenous infusion of dopamine

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18
Q

An 18-year-old G1 P0 adolescent female, who is pregnant at 7 weeks’ gestation by last menstrual period, complains of a 2-day history of vaginal spotting and lower abdominal pain. She denies a history of sexually transmitted diseases. On examination, her blood pressure (BP) is 130/60 mm Hg, heart rate (HR) is 70 beats per minute, and temperature is 99°F (37.2°C). Her neck is supple and the heart examination is normal. The lungs are clear bilaterally. The abdomen is nontender and no masses are palpated. On pelvic examination, the uterus is 4-week size and nontender. There are no adnexal masses on pelvic examination. The quantitative β-hCG level is 700 mIU/mL and a transvaginal ultrasound reveals an empty uterus and no adnexal masses.

What is your next step in the management of this patient?

A

Follow up β-hCG in 48 hours

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19
Q

A 35-year-old G5 P4 woman at 39 weeks’ gestation is undergoing a vaginal delivery. She has a history of a previous myomectomy and one prior low-transverse cesarean delivery. She was counseled about the risks, benefit, and alternatives of vaginal birth after cesarean, and elected a trial of labor. She proceeded through a normal labor. The delivery of the baby is uneventful. The placenta does not deliver after 30 minutes, and a manual extraction of the placenta is undertaken. The placenta seems to be firmly adherent to the uterus.

  • What is the most likely diagnosis?
  • What is your next step in management for this patient?
A
  • Placenta accreta

- Hysterectomy

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20
Q

List 5 risk factors for placenta accreta

A
  • Placenta previa
  • Implantation over the lower uterine segment
  • Prior cesarean scar or other uterine scar
  • Uterine curettage
  • Fetal Down syndrome
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21
Q

A 22-year-old nulliparous woman complains of a 2-week history of vaginal discharge and vaginal spotting after intercourse. She denies a history of sexually transmitted diseases and currently does not use any contraceptive agents. Her past medical history is unremarkable. Her last menstrual period began 1 week ago and was normal. On examination, her
blood pressure is 100/60 mm Hg, heart rate 80bpm, and temperature is 37.2°C. The heart and lung examinations are normal. Her abdomen is nontender and without masses. Her pelvic examination shows purulent vaginal discharge, which on Gram stain shows intracellular gram-negative diplococci. Her pregnancy test is negative.

  • What is the most likely diagnosis?
  • What is the next step in therapy?
  • What are the complications of this problem?
A
  • Most likely diagnosis: Gonococcal cervicitis.
  • Next step in therapy: Intramuscular ceftriaxone for gonorrhea, and oral azithromycin (or doxycycline) for chlamydial infection.
  • Complications of this problem: Salpingitis, which may lead to infertility or increased risk of ectopic pregnancy. Disseminated gonorrhea is also possible.
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22
Q

When a pregnant woman has an open cervical os with uterine cramping and history of passage of tissue, what is her most likely diagnosis? What would be the best therapy option?

A
  • Incomplete abortion

- Uterine curettage

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23
Q

What is the most common cause of first-trimester miscarriage?

A

Fetal karyotypic abnormality

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24
Q

What are some characteristics of a molar pregnancy?

A
  • Vaginal spotting
  • Absence of fetal heart tones
  • Size greater than dates
  • “Snowstorm” on ultrasonography
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25
Q

What is the age range of perimenopause?

A

40-51yo (avg 47yo)

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26
Q

47yo female with night sweats, hot flashes, and flushing. She cannot sleep due to these symptoms. How would you treat her?

A

Hormone replacement therapy: estrogen if no uterus
Estrogen + progesterone if uterus is present
*use lowest effective dose for

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27
Q

List FIVE symptoms of hypoestrogenemia in the perimenopausal woman

A
  • Vasomotor (night sweats, hot flashes, flushing)
  • Decreased epithelial thickness
  • Vaginal atrophy
  • Vaginal dryness
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28
Q

What investigations would you do in a perimenopausal woman to confirm this diagnosis? List FOUR

A
  • Serum FSH (up)
  • Serum LH (up)
  • Serum TSH - R/O Hypothyroid
  • Fasting blood glucose/A1c/OGTT - R/O Diabetes mellitus
  • BP - for HTN
  • Mammography if not done - screen breast cancer
29
Q

What are the indications for bone mineral density test?

A

Dual-Energy X-ray Absorptiometry (DEXA)

i) ≥65yo
ii) Postmenopausal with #
iii) Osteoporosis risk (i.e. early ovarian failure)

30
Q

In women undergoing perimenopause, what are the THREE things you should screen on history?

A
  • Grief or midlife adjustment
  • Depression
  • EtOH abuse
31
Q

Describe the latent phase of labour

A
Cervical effacement (thinning)
Cervix dilation
32
Q

What is the criteria for active phase of labour

A

Cervix > 4cm dilation

33
Q

What is the criteria for protraction of labour?

A

Cervix

34
Q

How do you define arrest of labour? What THREE things should you consider and how would you deal with each?

A

NO progress of labour for AT LEAST 2hrs

  • Power = oxytocin
  • Passage = Cephalopelvic disproportion = C/S
  • Passenger = fetal size/presentation = C/S
35
Q

What are the FOUR stages of labour?

A

Stage 1 = Cervix dilation
Stage 2 = Cervix dilation to delivery
Stage 3 = Delivery of fetus to delivery of placenta
Stage 4 = Delivery of placenta

36
Q

During pregnancy what volume of human chorionic gonadotropin hormone makes transvaginal ultrasonography useful?

A

1500-2000 mIU/ml

37
Q

A 26yo G2P1 female 12wks presents to Beaverlodge with severe abdominal pain with spotting that began today. BP 90/50, HR 120bpm. Her eyes appear sunken. What is her most likely diagnosis?

A
Ectopic pregnancy rupture
Classic presentation:
-Severe abdominal pain/Adnexal pain
-Severe volume depletion
-Hypotension
38
Q

A 26yo G2P1 female 12wks presents to Beaverlodge with severe abdominal pain with spotting that began today. BP 90/50, HR 120bpm. Her eyes appear sunken. What investigations would you order?

A
Some labs you would consider:
Hgb - anemia
White blood cell count - infection
HCG - pregnancy confirmation
*NEEDS laproscopy or exploratory laparotomy
39
Q

Your patient is found to have an ectopic pregnancy on transvaginal ultrasound but is otherwise asymptomatic, how would you manage this patient. (Ectopic you saw with Uretsky)

A

Ectopic asymptomatic pregnancies

40
Q

Your patient with an ectopic pregnancy presents for treatment. Blood work returns to find her Rh-. How should you proceed?

A

Rhogam to prevent isoimmunization

41
Q

What is the most definitive treatment for placenta accreta?

A

Hysterectomy

42
Q

Define: Placenta accreta
Placenta increta
Placenta percreta

A

Placenta accreta = placenta stuck to decidua basalis layer
Placenta increta = in myometrium
Placenta percreta = through myometrium usually onto bladder

43
Q

Compare and contrast the differences between a threatened abortion and inevitable abortion.

A

Threatened abortion =

44
Q

Compare and contrast incomplete abortion and complete abortion

A

Incomplete abortion =

45
Q

What is a missed abortion?

A

Fetal demise,

46
Q

How would you manage a threatened versus an inevitable abortion?

A

Threatened = serial HCG + transvaginal ultrasonography
Inevitable = Weigh Dilation & Curetage vs expectant management
***need histologic analysis of tissue if any passed

47
Q

How would you manage an incomplete versus complete abortion?

A
Incomplete = D&C
Complete = F/U HCG to ensure decreasing or absent
48
Q

What are complications of an incomplete abortion?

A

Hemorrhage and infection

49
Q

How would you manage a missed abortion medically?

A

D&C vs expectant management

50
Q

What is an incompetent cervix? List FIVE risk factors. How would you manage medically?

A

Incompetent cervix = cervix dilated without uterine contraction
Risk factors:
-Cervical conization
-Congenital (short cervix or collagen disorder)
-Cervix trauma
-Prolonged 2nd stage of previous labour
-Uterine overdistention (multiple gestations)
Tx-Cerclage

51
Q

Molar pregnancy typically present with:

A

Vaginal spotting
Absent fetal heart sounds
Size greater than dates
++ increase HCG

52
Q

How do you treat a molar pregnancy?

A

Suction Dilation and Curetage
Follow HCG weekly
Chemotherapy if HCG persists

53
Q

32 year old G3P2 at 38wks has gone into labour, upon delivery the head protrudes but then retracts. What is this sign? What is the most likely diagnosis? How would you manage?

A

Turtle Sign
Dx: Shoulder dystocia
Mx: McRoberts maneuver (hips flexed into abdomen), suprapubic pressure to unhinge the shoulder.
-Consider corkscrew rotation to 180º, deliver posterior shoulder
-Last resort: replace head and go to cesarean section

54
Q

Shoulder dystocia has TWO complications:

A

Post-partum hemorrhage
Erb’s palsy - C5-C6 nerve root injury in the brachial plexus (waiter’s tip=arm adducted, internal rotation, pronated, wrists flexed)

55
Q

What are the risk factors of shoulder dystocia? (4)

A

Gestational diabetes
Multiparous
Fetal Macrosomia
?Obesity

56
Q

What are THREE investigations you could use to diagnose endometrial carcinoma?

A

**Endometrial Biopsy
Hysteroscopy
Transvaginal ultrasonography

57
Q

What are the risk factors for endometrial biopsy. List TEN

A

-Early menarche
-Late menopause
-Nulliparity
-Diabetes mellitus
-Hypertension
-Obesity
-Past medical history/Family history of Breast/Ovarian Cancer
-Estrogen secreting ovarian cancer
-Hormone replacement therapy with unopposed estrogen
-chronic anovulation
-

58
Q

Women with post-menopausal bleeding, what must you rule out?

A

Endometrial Carcinoma***

DDx: Endometral polyp, Endometrial atrophy

59
Q

How would you treat endometrial cancer?

A

Hysterectomy

Stage: Omentectomy, lymph node dissection, peritoneal washings

60
Q

What is the classic presentation of placental previa?

A

Painless bleeding after mid second trimester.

Often noticed post coital spotting

61
Q

What is the first test you should order in patient you suspect of having placental previa?

A

Transvaginal ultrasonography

62
Q

How would you treat placental previa?

A

> 35wks = Cesarean section

63
Q

How do placental abruption and placental previa differ?

A

Abruption is painful antenatal bleeding associated with coagulopathy (DIC)
Previa is painless antenatal bleeding

64
Q

What are the THREE types of placental previa?

A

Complete-placenta cover’s OS
Partial-partially covers the OS
Marginal-abuts the OS
*Low lying placenta-edge of placenta 2-3cm of internal os

65
Q

List FIVE risk factors for placenta previa

A
Grand multiparity
Prior C/S delivery
Prior uterine curetage
Previous placenta previa
Multiple gestation
66
Q

List TWO reasons why placenta previa should not be delivered vaginally

A

Lower uterine segment produce poor contractions

Increase PPH risk

67
Q

Placental abruption has EIGHT risk factors

A
  • Hypertension
  • Cocaine use
  • Short umbilical cord
  • Trauma
  • Uteroplacental insufficiency
  • Submucous leiomyomata
  • Sudden uterine decompression (hydramnios)
  • Cigarette smoking
  • Preterm premature rupture of membranes
68
Q

What is a major complication of placental abruption should you worry about?

A

Disseminated Intravascular Coagulopathy