Case Files 37-42 (C) Flashcards

1
Q

Explain antalgic gait

A

Occurs when the “stance phase” of gait is shortened, usually because of pain during weight bearing

Remember: normal gait consists of two phases (swing and stance, with stance accounting for ~60% of the cycle)

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2
Q

The most common nontraumatic hip pathology in adolescents

A

Slipped Capital Femoral Epiphysis (SCFE)

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3
Q

Hip pathology will frequently present with pain in the…

A

groin, thigh, and knee

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4
Q

Pain with internal rotation of the hip

+

External rotation on passive flexion

A

SCFE

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5
Q

What is the most sensitive mark (on PE) of hip pathology in children

A

Restricted internal rotation followed by a lack of abduction

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6
Q

The FABER test can find pathology located in the…

A

SI joint

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7
Q

Fever greater than ___ and ESR gerater than ___ is 97% sensitive for septic hip joint

A

Fever > 99.5

ESR > 20

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8
Q

Monoarticular with systemic signs (eg, fever)

A

Think septic arthritis

Children with septic hip joint will often lay with their hip flexed, abducted, and externally rotated

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9
Q

What are the most common pathogens involved in children with septic hip?

A

< 4 months: GBS and Staph aureus

4 months - 5 years: Staph aureus and Strep pyogenes

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10
Q

Spiral fracture of the tibia that results from twisting while the foot is planted

A

Toddler’s fracture

Setting = acute limp or change in ambulation

*If the child had a painless limp from the time they learned to walk think congenital dysplasia

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11
Q

Transient synovitis

A

A self-limited inflammatory response that often follows a viral infection, leading to hip pain in children ages 3-10

Low-grade to no fever, normal WBC, normal ESR

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12
Q

Kocher criteria

A

Used to assess risk for septic arthritis in children

Four criteria:

  1. Fever > 101.3
  2. Nonweight bearing
  3. ESR > 40
  4. WBC > 12,00
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13
Q

Purulent aspirate with WBC > 50,000

vs

Yellow/clear aspirate with WBC <10,000

A

Septic joint

vs

Transient synovitis

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14
Q

Avascular necrosis of the femoral head

A

AKA Legg-Calvé-Perthes (LCP)

More common in boys than girls

Although any disruption of blood flow to the femoral capital epiphysis, such as trauma or infection, can cause avascular necrosis the etiology of LCP is unknown

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15
Q

Capital Femoral Epiphysis

A

Growth plate that connects the metaphysis (femoral head) to the diaphysis (shaft of the femur)

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16
Q

Treatment for SCFE

A

Surgical pinning (do not let them walk after making diagnosis)

33% will develop avascular necrosis and 33% will develop SCFE in the contralateral hip

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17
Q

Pain that wakens a child at night

A

Suspicious for malignancy

“Growing pains” is a diagnosis of exclusion (it should be considered if the pain is only at night, is bilateral, and if no other pathology is found)

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18
Q

A 6-year-old young boy is brought in for evaluation of a painful hip. He has been limping and not wanting to walk for the past 2 days. He has had no obvious injury. He feels better after taking ibuprofen. He has not had a fever, although he had “the flu” last week. Vitals are normal. Some pain with internal rotation. He walks with a pronounced limp. Can he be sent home?

A

After getting a CBC and ESR

If they are in normal limits he likely has transient synovitis and can be treated with an NSAID with the expectation of a recovery in a few days

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19
Q

A 6-year-old boy has a 2-month history of slight limp. No PMHx and no medications. Normal vitals, but an antalgic gait and decreased ROM in the L hip (internal). Mild pain on palpation of the anterior capsule on the L side. X-ray shows fragmentation of the femoral head. What is the most likely diagnosis?

A

Legg-Calvé-Perthes disease

Often a self-healing disorder. Treatment is focused on limiting pain and avoiding functional loss.

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20
Q

Physical exam findings of suprapubic pain and costovertebral tenderness

A

Suggestive of UTI and most likely acute pyelonephritis

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21
Q

Most common organisms leading to UTIs

A

E coli

Proteus

Klebsiella

Staph epidermidis

Pseudomonas

Candida

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22
Q

Drugs that are commonly associated with “drug fever”

A

B-lactams

Sulfa derivatives

Anticonvulsants

Allopurinol

Heparin

Amphotericin B

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23
Q

A rare AD disorder charaterized by fever > 104, tachycardia, metabolic acidosis, rhabdomyolysis, and calcium accumulation in skeletal muscle leading to rigidity

A

Malignant Hyperthermia

May occur up to 24 hrs after exposure to anesthetic agents such as halothane and succinylcholine

Treatment: discontinue offending agents, supportive therapy (antipyretics, oxygen hyperventilation, cooling blankets, sodium bicarbonate, and dantrolene IV)

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24
Q

Most common postoperative complication

A

Fever

25
Q

5 W’s of post-op fever

A

Wind (pneumonia)

Water (UTI)

Walk (DVT)

Wound (SSI)

Wonder where/drugs (Abscess or Fever)

26
Q

Causes of immediate postoperative period

A

Medications

Blood products

Malignant Hyperthermia

Bacteremia

27
Q

If fever occurs within 36 hours post-laparotomy what two important infectious etiologies should you consider?

A

Bowel injury with leakage of gastrointestinal contents

Invasive soft-tissue wound infection (caused by β-hemolytic streptococci or Clostridium species)

*Toxic Shock Syndrome caused by Staph aureus is a rare condition

28
Q

Postoperative pneumonia is typically caused by

A

polymicrobial

Enterobacteriaceae and S aureus or Enterobacteriaceae and Streptococci

29
Q

When and which type of antibiotics do you give for aspiration penumonia?

A

Antibiotics are typically given following a witnessed aspiration and discontinued after 48-72 hours with no development of infiltrates

Gram (-) coverage is required, with the current choice being piperacillin/tazobactam or ticarcillin/clavulanate

30
Q

Homan sign

A

Pain in the calf on foot dorsiflexion = DVT

Fever caused by DCT usually occurs on the 5th postoperative day

31
Q

Stridor vs Wheezing

A

Stridor: wheezing coming from obstruction of the large airway that has a constant pitch and intensity throughout the entire inspiratory effort

Wheezing: a musical sound heard on pulmonary ausculatation produced by the oscillating walls of airways that had been narrowed by mucus, inflammation, and so on

Extra-thoracic vs Intraluminal Obstruction

32
Q

Acute wheezing in children

A

Infectious (eg, bronchiolitis)

or

Mechanical obstruction (eg, FBAO)

33
Q

Recurrent wheezing in children

A

Bronchomalacia

CV disease (eg, vascular rings and slings)

GERD

Immunologic disorders (eg, bronchopulmonary dysplasia, cystic fibrosis)

34
Q

Viral infection cuasing nonspecific inflammation of the small airways, peaking during the winter months

A

Bronchiolitis

RSV accounts for 70% of cases (rest are caused by parainfluenza, adenovirus, influenza, Mycoplasma pneumonia, Chlamydia pneumonia, and metapneumovirus)

35
Q

Treatment for bronchiolitis

A

Supplemental oxygen if SpO2 < 90% and supportive care (clear evidence of effectiveness in RSV bronchiolitis)

Supportive care = supplemental humidified oxygen, fluids, and suctioning

36
Q

What preventative therapy can be given for children < 2 with increased risks for chronic lung disease, history of prematurity, or with congenital heart disease?

A

RSV immunoglobulin (RespiGam)

and

Palivizumab (Synagis)

37
Q

Most common cause of airway obstruction in children aged 6 months to 6 years

Also the leading cause of hospitalization for children younger than 4 years

A

Croup

Viral infection that causes inflammation of the subglottic region of the larynx

Croup syndrome encompasses: laryngotracheitis, laryngotracheobronchitis, laryngotracheobronchopneumonitis, and spasmodic croup

38
Q

Croup is caused by…

A

The parainfluenza viruses (I, II, III) are responsible for 80% of croup cases, with parainfluenza I accounting for most episodes and 50-70% of hospitalizations

Other causes: adenovirus, reovirus, metapneumovirus, varicella, herpes simplex virus, human bocavirus, coronavirus, and influenza A and B

39
Q

Frontal neck x-rays shows a “steeple sign”

A

Croup

Indicative of subglottic narrowing of the tracheal lumen

40
Q

Bacterial infection of the supraglottic tissue

A

Epiglottitis

41
Q

Management of a patient with suspected epiglottitis

A

Take to the OR

Confirm diagnosis with experienced surgeon and anesthesiologist in the room (airway)

Thumb sign on X-ray

42
Q

Lubiprostone (Amitiza)

A

Selectively activates intestinal chloride channels and increases fluid secretion

FDA approved for IBS in women with constipation

43
Q

IBS affects women _____ more times than men

A

2-3

44
Q

Rome criteria for IBS

A

Recurrent abdominal pain at least 3 days per month for the past 3 months, associated with 2 or more of the following:

  • improvement with defecation
  • onset associated with a change in stool frequency
  • onset associated with a change in stool consistency
45
Q

Treatment for IBS

A

Abdominal pain: dicyclomine and hyoscyamine (antispasmodics)

Constipation: fiber (psyllium) and fluid, lubiprostone

Diarrhea: loperamide, alosetron

46
Q

Why is it dangerous to use cocaine and alcohol

A

Can lead to the formation of cocaethylene, which intensifies cocaine’s effects

Cocaethylene is associated with a greater risk of coronary vasospasm than cocaine alone, resulting in MI and sudden death

47
Q

True/False: genetic susceptibility accounts for 40-60% of a person’s vulnerability to addiction

A

True

48
Q

Barbiturates

Benzodiazepines

GHB

Methaqualone

A

Depressents

Barbiturates can have a life-threatening withdrawal

49
Q

Amphetamines

Cocaine

MDMA

Methamphetamine

Methylphenidate

Nicotine

A

Stimulants

50
Q

Treatment for opiod withdrawal

A

Methadone

Buprenorphine

Naltrexone

Nalaxone (IV opioid antagonist) = treatment of choice for acute opoid intoxication

51
Q

Treatment of nicotine withdrawal

A

Gum, patch, spray, lazenges

Bupropion

Vareniciline

52
Q

Common treatment of alcohol withdrawal

A

Naltrexone

Disulfiram

Acamprosate

*Evidence has found naltrexone/acamprosate to be the most effective treatment of alcohol dependence when used in conjunction with behavioral therapy

53
Q

MORPHINE-ABC

A

Mnemonic for signs and symptoms

Miosis, Out of it, Respiratory depression, Pneumonia, Hypotension, Infrequency (constipation/urinary retention), Nausea, Emesis, Analgesic, Bradycardia, Coma

54
Q

Midsystolic click +/- late systolic murmur

A

Mitral Valve Prolapse

Most common valvular heart defect in the US

55
Q

Wolff-Parkinson-White syndrome

A

Caused by an accessory track between the atria and the ventricles that conducts electrical impulses in addition to the AV node

Classic ECG finding = slurring on the upstroke of the QRS complex (aka delta wave)

56
Q

Long QT Syndrome

A

caused by mutations in multiple genes and can have an autosomal dominant pattern

seen more commonly in females

any patient with a QT interval greater than 500 msec is at increased risk for dangerous dysrhythmias

57
Q

Most common cause of sudden cardiac death in adolescents in the US

A

Hypertrophic cardiomyopathy

Heart murmur, if present, will usually be systolic and will be accentuated by Valsalva maneuver

58
Q

What is the most common cause of palpitations

A

Primary rhythm disturbance (40% of cases)