CASE Flashcards
Lack of facial expression is indicative of?
Parkinson’s
Startled expresion indicative of?
Hyperthyroidism
Poor eye contact indicative of?
Depression
Apathy and pale puffy skin indicative of?
Hypothyroidism
Lugubrious expression and bilateral ptosis indicative of?
Myotonic dystrophy
Agitated demeanour indicative of?
Anxiety, hyperthyroidism, hypermania
Long, thin fingers a sign of?
Marfan’s syndrome (called arachnodactyly)
Spoon shaped nails?
Iron deficiency (koilonychia)
White nails?
hyperalbnuminaemia (leukonychia)
White transverse grooves on nails?
Beau’s lines (appear after severe illness)
Splinter haemorrhages?
Indicative of infective endocarditis
Distal nail separation?
Psoriasis (onycholysis)
What condition do you get dilated capillaries in proximal nail fold?
SLE
What joints affected in RA?
Metacarpophalangeal and proximal interphalangeal
What joints affected in OA and psoriatic arthropathy?
Distal interphalangeal
Signs of carpal tunnel syndrome?
Wasting of thenar muscles
Tremor in tongue due to?
Delirium tremens or Parkinson’s
Fasciculations in tongue due to?
Lower motor neurone disorders
Macroglossia sign of?
Acromegaly, amyloidosis or tumour
Red lines and rings on tongue that change over weeks and days?
B2 deficiency (called geographic tongue)
Smooth reddened tongue?
In alcoholics and coeliacs (called glossitis)
Rubbery lymph nodes indicative of?
Hodgkin’s
‘Matted’ lymph nodes indicative of?
TB
Hard lymph nodes indicative of?
Cancer
Tender lymph nodes indicative of?
Infection
Fixated lymph nodes indicative of?
Malignancy
Bruising under skin called?
Purpura
Large bruises called?
Ecchymosis
Pinpoint bruises called?
Petechiae
What waist size for health risk in men and women?
37” men and 32” women
Sign of scurvy?
Easy bruising, extensive bruising
Sign of vitamin A deficiency?
Xeropthalmia (night blindness), keratomalacia (eye disorder where cornea becomes opaque
Sign of vitamin D deficiency?
Rickets in children, osteomalacia in adults
Sign of vitamin K deficiency?
Bleeding disorder
Sign of vitamin B1 deficiency?
Beriberi (heart failure or neuropathy)
Sign of vitamin B2 deficiency?
Glossitis, stomatitis
Sign of vitamin B3 deficiency?
Pellagra (Dermatitis, diarrhoea, and dementia)
Sign of vitamin B6 deficiency?
Polyneuropathy
Sign of biotin deficiency?
Dermatitis, alopecia, parathesiae
Sign of folate deficiency ?
Megoblastic anaemia
Sign of B12 deficiency?
Megoblastic anaemia and neurological disorders
What is oedema a sign of?
Fluid overload or hypoalbuminaemia (can use JVP to distinguish as it will be elevated in overload)
Definition of postural hypotension?
Drop of 20mmHg systolic when standing
Yellow plaques on skin or tendons?
Xanthomata
Yellow plaques around eyelids?
Xanthelasma
Flame shaped haemorrhage with white centre on the retina a sign of?
Called Roth’s spots - bacterial endocarditis (also leukaemia, diabetes, pernicious anaemia)
What are the pulses?
Radial, brachial, carotid, femoral, popliteal, posterior tibial, dorsalis pedis
How does heart rate change with breathing?
Accelerates with inspiration, slows with expiration
How does blood pressure change with breathing?
Falls with inspiration, rises with expiration
How does the JVP change with breathing?
Falls with inspiration, rises with expiration
Signs of coarctation in children?
Pulses in arms normally normal, but leg pulses there is a delay and reduced volume
Signs of coarctation in adults?
Hypertension and heart failure
Beat to beat variation in pulse volume, with a normal rhythm?
Pulsus alternans (rare and happens in advanced heart failure)
Exaggeration of the normal variability pulse volume with the respiratory cycle?
Pulsus paradoxus (in tamponade and decreased intrathoracic pressure, ie severe asthma) - a decrease of 15mmHg on inspiration is pathological
What is a collapsing pulse? And what is is a sign of?
Peak of the pulse wave arrives early and followed by rapid descent. Is exaggerated with the arm raised.
Aortic regurgitation
What is a slow rising pulse? And what is is a sign of?
Gradual upstroke with a reduced peak occurring late in systole.
Severe aortic stenosis
What is a bisferiens pulse? And what is is a sign of?
2 systolic beats separated by a dip.
Mixed aortic regurgitation and stenosis
What is blood pressure monitored with?
Sphygmomanometer
Causes of secondary hypertension?
Pheochromocytoma (tumour of adrenal medulla)
Conn’s syndrome (tumour of adrenal cortex -aldosterone)
Cushing’s syndrome (microadenoma of pituitary -ACTH)
Coarctation of the aorta
Polycystic kidney disease
What are Korotkoff sounds?
Noises from under the distal half of the BP cuff between systole and diastole because the artery collapses completely and reopens with every heartbeat)
What pressure does JVP represent?
Central venous or right atrial pressure and indirectly right ventricle function
What do the points of the jugular pulse wave represent (draw it!)
a = atrial systole
c = closure of the tricuspid valve
v = peak pressure in the right atrium immediately prior to opening of the tricuspid
a to x = descent due to downward displacement of tricuspid ring during systole
v to y = descent at commencement of ventricular filling
Elevated JVP sign of?
Right sided heart failure (ventricular), acute PE, COPD with cor pulmonale, mechanical obstruction of vena cava
What is Kussmaul’s sign in the JVP and what is it a sign of?
A paradoxical rise of JVP on inspiration (normally falls).
Seen in tamponade, severe right ventricular failure, and restrictive cardiomyopathy
What is a prominent ‘a’ wave in the JVP a sign of?
Any condition with delayed or restricted right ventricular filling (eg pulmonary hypertension or tricuspid stenosis)
What are canon waves in the JVP and what is it a sign of?
Giant ‘A’ waves, occur when right atrium contracts against closed tricuspid (tricuspid stenosis)
Irregular canon waves seen in complete heart block
Regular canon waves seen during junctional bradycardias and some ventricular tachycardias
What is a ‘cv’ wave in the JVP a sign of?
Fusion of c and v resulting in increased wave and associated with a pulsatile liver. Seen in tricuspid regurgitation
What are absent ‘a’ waves in the JVP a sign of?
Atrial fibrillation
What heart sounds do you hear best at the cardiac apex?
1st heart sound
3rd and 4th heart sounds
Mid diastolic murmur of mitral stenosis
What heart sounds do you hear best at the lower left sternal border ?
Early diastolic murmur of aortic regurgitation
Pansystolic murmur of tricuspid regurgitation
What heart sounds do you hear best at the upper left sternal border ?
2nd heart sound
Pulmonary valve murmurs
Pansystolic murmur of ventricular septal defect
What heart sounds do you hear best at the upper right sternal border ?
Systolic ejection murmurs IE aortic stenosis
Hypertrophic obstructive cardiomyopathy
What heart sounds do you hear best at the left axilla ?
Radiation of pansystolic murmur of mitral regurgitation
What heart sounds do you hear best below left clavicle?
Patent ductus arteriosus
Common causes of pathological 3rd heart sound?
Left ventricular failure, mitral regurgitation
Can occur in heart failure with a tachycardia
What is a 4th heart sound?
Soft and low pitched, nest heard with bell of stethoscope.
Caused by forceful contraction of atrium against still ventricle
How best to hear pericardial rub?
Diaphragm of stethoscope and breath help on expiration
What is Cheyne-Stokes respiration?
Cyclical increasing rate and depth of breathing followed by diminishing effort ending in apnoea
What is Kussmaul respiration?
Deep sighing respirations in response to metabolic acidosis
Eryhthema nodosum on shins might indicate?
Sarcoidosis, IBD and pregnancy
Causes of clubbing?
Tumours, interstitial lung disease, bronchiectasis, CF, bacterial endocarditis, UC, CD
Tremor in hands could be a sign of?
Excessive use of B-agonist
Flapping tremor a sign of?
CO2 retention
Name lymph nodes in the neck
Supraclavicular, cervical (SCM), posterior (behind SCM), postauricular, preauricular, submental, submandibular, pretracheal
Prominence of the sternum (pigeon chest?) and the other sign that comes with this ?
Pectus carinatum
Harrison’s sulci- indrawing of ribs to form horizontal grooves
Depression of the sternum
Pectus excavatum
What is hyper resonant chest on percussion a sign of?
Pneumothorax
What is dull chest on percussion a sign of?
Consolidation, collapse, fibrosis
What is stony dull chest on percussion a sign of?
Effusion, haemothroax
What are crackles on the chest a sign of?
Early inspiration - small airway disease
Middle- pulmonary oedema
Late - pulmonary fibrosis, secretions in COPD, pneumonia
Biphasic, coarse - broniectasis
Causes of respiratory acidosis?
Severe acute asthma, severe pneumonia, COPD, kyphoscoliosis
CO2 and HCO3 are raised
Causes of respiratory alkalosis?
Hyperventilation due to anxiety, stroke, salicylate poisoning
(CO2 and HCO3 are decreased)
Causes of metabolic acidosis?
DKA, poisoning, renal failure (CO2 and HCO3 are decreased)
Causes of metabolic alkalosis?
Loss of acid from severe vomiting, excess diuretic therapy, hyperaldosteronism, Cushing’s syndrome
(CO2 and HCO3 are raised)
What is recorded in spirometry?
Forced vital capacity (FVC)- total exhaled (reaches residual volume)
Amount exhaled in one second (FEV1)
FEV1/FVC ratios useful for?
Usually above 75%
Decreased ratio indicative of obstructive disease
Preserved ratio but decreased FVC indicative of restrictive disease (fibrosis, sarcoidosis)
Night time wakening with coughing and wheeze a sign of?
This is characteristic of poorly controlled asthma
Causes of chronic cough with no X-ray changes?
Smoking, sinusitis, GORD, asthma or ACE inhibitors
Surface markings of the liver?
5th intercostal space on full inspiration (upper border)
Costal margin in mid-clavicular line on full inspiration (lower border)
Surface markings of spleen?
Underlies left ribs 9, 10 and 11 posterior to mid axillary line
Surface markings of gallbladder?
Intersection of right lateral vertical plane and costal margin (ie tip of 9th costal cartilage)
Surface markings of pancreas?
Neck lies at level of L1, head below and right, the tail above and left
Surface markings of kidneys?
Upper poles deep to the 12th rib posteriorly 7cm from midline - right is 2-3cm lower than the left
What is fancy word for dry mouth?
Xerostomia
What is fancy word for bad breath?
Halitosis due to gingival or pharyngeal infection
What is cacogeusia?
Foul taste in mouth
What is fancy word for altered tase sensation ?
Dysguesia
What is the Iliopsoas sign/test?
Flex thigh against resistance. Pain is a positive test- indicates inflammation involving the psoas muscle. (retroileal appendicitis, iliposoas abscess, perinephric accesses)
What is Murphy’s sign?
Pt takes a deep breath in while you gently palpate in right upper quadrant of abdomen - as the gallbladder comes into contact with fingers pain is elicited - sign of acute cholecystitis
What is Rovsing’s sign?
Palpation in left iliac fossa produces pain in right iliac fossa - sign of acute appendicitis
What are Grey-Turner’s and Cullen’s signs?
Bleeding into falciform ligament - bruising around umbilicus (Cullen’s) or in the loins (Grey-Turner’s).
Sign of haemorrhagic pancreatitis, aortic rupture, ectopic pregnancy
What is menarche?
When periods start
What is measured in pregnancy test?
B-HCG - useful for ectopic pregnancies
Ovarian cancer marker?
CA125