Case 22

Question 1

Describe the principles underlying antagonism of residual nondepolarizing neuromuscular blockade.

Question 2

2. How is acetylcholinesterase inhibited?

Question 3

3. Name clinically relevant acetylcholinesterase inhibitors and their onsets of action.

Question 4

4. What are the usual doses and expected durations of action for acetylcholinesterase inhibitors?

Question 5

5. Why is it necessary to administer an anticholinergic drug with an acetylcholinesterase inhibitor?

Question 6

6. What other class of drugs is under investigation for antagonism of nondepolarizing neuromuscular blockade?