Cartilage And Bone Flashcards

0
Q

What are the three types of cartilage?

A

Hyaline, elastic, fibrocartilage

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1
Q

What is cartilage?

A

A resilient, avascular connective tissue consisting of chondrocytes which produce and maintain an extensive extracellular matrix.

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2
Q

In addition to the elements of a hyaline cartilage matrix, what type of collagen is in fibrocartilage?

A

Type I collagen.

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4
Q

What are the two main functions of cartilage?

A

Provide support for soft tissues and sliding of joints.

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5
Q

What do you call a group of chondrocytes recently divided?

A

Isogenous group.

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6
Q

Where is hyaline cartilage found?

A

Larynx, trachea, bronchus, ear, nose, ribs, articulating surfaces.

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7
Q

What is perichondrium?

A

Dense connective tissue surrounding hyaline and elastic cartilage.

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8
Q

How is perichondrium involved in cartilage growth?

A

Appositional growth, contains fibroblast-like cells which develop into chondroblasts, then chondrocytes.

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9
Q

Why do articulating surfaces not have perichondrium?

A

It would be worn away in the joint.

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10
Q

How is the synthetic activity of chondrocytes directed?

A

By mechanical, electrical and chemical signals created by pressure loads applied on the cartilage.

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11
Q

What is contained in the matrix of hyaline cartilage?

A

Hyaluronate proteoglycan aggregates and type II collagen.

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12
Q

How do articulating surfaces receive nutrients if not through perichondrium?

A

Synovial fluid.

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13
Q

What is the deposition of further matrix by isogenous groups known as?

A

Interstitial growth.

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14
Q

How is the intercellular matrix resilient to varying pressure loads?

A

It is highly hydrated.

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15
Q

What do chondrocytes lie in?

A

Lacunae

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16
Q

Where is fibrocartilage found?

A

Intervertebral discs, pubic symphysis, articular discs of knee menisci and temporomandibular and sternoclavicular joints.

17
Q

What part within a bone is produced by hyaline cartilage?

A

Epiphyseal growth plate

18
Q

What type of matrix surrounds lacunae and what does it have a high concentration of?

A

Territorial matrix, sulphated GAGs

19
Q

What two types of tissue is fibrocartilage a combination of?

A

Dense regular connective tissue, hyaline cartilage

20
Q

What is the relationship between chondrocytes and extracellular matrix?

A

Chondrocytes produce and maintain the EM.

22
Q

Why is fibrocartilage considered to have no perichondrium?

A

Blends with other tissues such as tendons or hyaline cartilage.

23
Q

What is the extracellular matrix replaced by in fibrocartilage?

A

Coarse collagen fibres which are parallel to direction of main stress on structure.

24
Q

What are the two types of bone?

A

Cancellous and compact.

25
Q

What are the two arrangement of lamellae in compact bone?

A

Concentrically

26
Q

What two cell types are in fibrocartilage?

A

Chondrocytes, fibroblasts

27
Q

Where is elastic cartilage found?

A

External ear (pinna), external acoustic meatus, epiglottis, Eustachian tube