Cartilage Flashcards
Cartilage is (vascular/avascular) and contains (nerves/no nerves)
Avascular and no nerves
Chondroblasts
secrete cartilage matrix that surrounds cells in a LACUNA where cells mature into Chondrocytes
Chondrocytes
Mature cartilage cells
Lacuna
Space that houses mature chondrocytes
What type of collagen is dominate in cartilage?
TYPE II Collagen is dominant in cartilage (Type I is dominate in connective tissue)
Territorial Cartilage matrix
directly surrounds chondrocytes
Interterritorial cartilage matrix
Surrounds several territorial groups
Perichondrium
a girdle-type net of dense irregular CT with vascular and nutrient supply. Site of new cartilage cells during growth
Name the two layers of perichondrium
Fibrous Layer
Chondrogenic Layer
Perichondrium Fibrous Layer
Type I Collagen and elastin
Forms the transitional layer
Perichondrium Chondrogenic Layer
Type II Collagen
Chondroblasts grow into mature chondrocytes within their lacuna in this layer
3 types of Cartilage
Hyaline
Elastic
Fibrocartilage
Hyaline Cartilage
Most common, surrounded by perichondrium
type II collagen
articular cartilage, larynx, ribs, trachea, embryonic development
Elastic Cartilage
3 E’s: External ear, epiglottis, Eustachian Tube
Surrounded by perichondrium
Type II cartilage
Fibrocartilage
lacks perichondrium
contains type I cartilage
Intervertebral discs, pubic symphysis, TMJ
What type of cartilage lacks perichondrium?
Articular cartilage, Fibrocartilage
Appositional Cartilage growth
increases in width
grows like rings on a tree, cartilage formed on existing cartilage
Interstitial cartilage growth
occurs when chondrocytes within lacuna divide
increase the length of cartilage, more dense
Inverse rule of joint cartilage
The more flexible the joint, the less stable.
The more stable the joint, the less flexible
Synoviocytes
cells of synovial fluid in joint capsule
Type A Synoviocytes
mAcrophAge like | MAIDS of the joint
phagocytic, lysosomes clean and clear articular cavity of debris
25% of joint cells
regulate inflammatory response
Type B Synoviocytes
fiBroBlast like | MOTHERS of the joint
make synovial fluid, produce hyaluronate to combine with synovial fluid, lubricates and nourishes the articular cartilage
Articular Cartilage: Superficial Zone
collagen fibers run parallel to surface
devoid of cells in most superficial layer
Articular Cartilage: intermediate zone
fibers run oblique to the surface
chondrocytes slightly larger and round
Articular Cartilage: Deep Zone
fibers perpendicular to articulating surface
form large radial columns
Articular Cartilage: Calcified
stains darker than matrix of other zones
rests on cortex of bone
