Cartilage Flashcards

1
Q

Cartilage is (vascular/avascular) and contains (nerves/no nerves)

A

Avascular and no nerves

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2
Q

Chondroblasts

A

secrete cartilage matrix that surrounds cells in a LACUNA where cells mature into Chondrocytes

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3
Q

Chondrocytes

A

Mature cartilage cells

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4
Q

Lacuna

A

Space that houses mature chondrocytes

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5
Q

What type of collagen is dominate in cartilage?

A

TYPE II Collagen is dominant in cartilage (Type I is dominate in connective tissue)

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6
Q

Territorial Cartilage matrix

A

directly surrounds chondrocytes

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7
Q

Interterritorial cartilage matrix

A

Surrounds several territorial groups

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8
Q

Perichondrium

A

a girdle-type net of dense irregular CT with vascular and nutrient supply. Site of new cartilage cells during growth

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9
Q

Name the two layers of perichondrium

A

Fibrous Layer

Chondrogenic Layer

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10
Q

Perichondrium Fibrous Layer

A

Type I Collagen and elastin

Forms the transitional layer

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11
Q

Perichondrium Chondrogenic Layer

A

Type II Collagen

Chondroblasts grow into mature chondrocytes within their lacuna in this layer

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12
Q

3 types of Cartilage

A

Hyaline
Elastic
Fibrocartilage

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13
Q

Hyaline Cartilage

A

Most common, surrounded by perichondrium
type II collagen
articular cartilage, larynx, ribs, trachea, embryonic development

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14
Q

Elastic Cartilage

A

3 E’s: External ear, epiglottis, Eustachian Tube
Surrounded by perichondrium
Type II cartilage

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15
Q

Fibrocartilage

A

lacks perichondrium
contains type I cartilage
Intervertebral discs, pubic symphysis, TMJ

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16
Q

What type of cartilage lacks perichondrium?

A

Articular cartilage, Fibrocartilage

17
Q

Appositional Cartilage growth

A

increases in width

grows like rings on a tree, cartilage formed on existing cartilage

18
Q

Interstitial cartilage growth

A

occurs when chondrocytes within lacuna divide

increase the length of cartilage, more dense

19
Q

Inverse rule of joint cartilage

A

The more flexible the joint, the less stable.

The more stable the joint, the less flexible

20
Q

Synoviocytes

A

cells of synovial fluid in joint capsule

21
Q

Type A Synoviocytes

A

mAcrophAge like | MAIDS of the joint
phagocytic, lysosomes clean and clear articular cavity of debris
25% of joint cells
regulate inflammatory response

22
Q

Type B Synoviocytes

A

fiBroBlast like | MOTHERS of the joint
make synovial fluid, produce hyaluronate to combine with synovial fluid, lubricates and nourishes the articular cartilage

23
Q

Articular Cartilage: Superficial Zone

A

collagen fibers run parallel to surface

devoid of cells in most superficial layer

24
Q

Articular Cartilage: intermediate zone

A

fibers run oblique to the surface

chondrocytes slightly larger and round

25
Q

Articular Cartilage: Deep Zone

A

fibers perpendicular to articulating surface

form large radial columns

26
Q

Articular Cartilage: Calcified

A

stains darker than matrix of other zones

rests on cortex of bone