Cards Test 2 Medications Flashcards

1
Q

Drugs most effective for HTN in younger white patients

A

ACE-I, CCB, BB

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2
Q

Drugs most effective for HTN in older white patients

A

CCB, diuretics

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3
Q

Drugs most effective for HTN in younger black patients

A

CCB

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4
Q

Drugs that are ineffective for HTN in younger black patients

A

ACE-I, BB

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5
Q

Drugs most effective for HTN in older black patients

A

CCB, diuretics

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6
Q

Drugs most effective for isolated systolic HTN

A

CCB, diuretics

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7
Q

Hydrochlorothiazide (type of drug)

A

Thiazide diuretic

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8
Q

Metazolone (type of drug)

A

Thiazide diuretic

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9
Q

Indapamide (type of drug)

A

Thiazide diuretic

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10
Q

HTN drug that causes ototoxicity

A

Loop Diuretic

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11
Q

Furosemide (type of drug)

A

Loop diuretic

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12
Q

Bumetanide (type of drug)

A

Loop diuretic)

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13
Q

Torsemide (type of drug)

A

Loop diuretic

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14
Q

Triameterene (type of drug)

A

Na+/K+ antagonist K+ sparing diuretic

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15
Q

Most common alpha2-agonist AE

A

dry mouth

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16
Q

HTN drug safe in pregnancy

A

Methyldopa

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17
Q

HTN drug that can also alleviate symptoms of BPH

A

Alpha-blockers

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18
Q

Clonidine (type of drug)

A

alpha2-agonist for HTN

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19
Q

The “-sin” drugs (type of drug)

A

Alpha-blockers for HTN

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20
Q

Difference between DHP and non-DHP calcium channel blockers

A

Non-DHPs focus have greatest effect in heart (reduce contractility and AV conduction).
DHPs are potent vasodilators and have little effect on heart

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21
Q

Verapamil (type of drug)

A

Non-DHP CCB

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22
Q

Diltiazem (type of drug)

A

Non-DHP CCB

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23
Q

Nifedipine (type of drug)

A

DHP CCB

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24
Q

Hydralazine (type of drug)

A

Direct vasodilator

25
Minoxidil (type of drug)
direct vasodilator
26
Sodium Nitroprusside (type of drug)
Potent arteriolar and venous dilator
27
DOC for hypertensive emergency
Sodium nitroprusside
28
"Renal protective" HTN drug
ACE-I and ARBs
29
Drug type to use when patient can't be on ACE-I
ARB
30
Initial agent for diabetic HTN
ACE-I
31
Initial agent for CAD or recent MI hypertension
BB
32
Initial agent for HTN patient with overactive thyroid
BB
33
Initial agent for HTN patient with tachyarrhythmia
BB
34
initial agent for HTN in HF patient
ACE-I
35
initial agent for HTN in chronic renal failure patient
ACE-I or CCB
36
Drug that raises standing blood pressure levels
Midodrine
37
Statins' effect on lipid profile
- reduces LDL 20-55% - reduces TG 7-30% - raises HDL 5-15%
38
Statins' AE
- myopathy | - increased liver enzymes (hepatic toxicity)
39
Absolute contraindications for statins
-liver disease
40
Statins' effect on atherosclerotic plaque
Causes plaque regression, but also increases the hard fibrous cap (increasing stability)
41
Fibrates MOA
Increase FA oxidation in the muscle and liver
42
Drug most effective at reducing VLDL
Fibrates
43
Fibrates' effect on lipid profile
- reduces VLDL - reduces TG 20-50% - reduces LDL 5-15% - raises HDL 10-20%
44
Drugs most effective at lowering LDL
Statins
45
Drug most effective at raising HDL
Nicotinic acid (niacin)
46
Only safe hyperlipidemic drugs for pregnancy
Bile acid sequestrants
47
Cholestyramine (type of drug)
bile acid sequestrant
48
Colestipol (type of drug)
bile acid sequestrant
49
Ezetimibe MOA
cholesterol absorption inhibitor
50
Effect of Ezetimibe + Statins
Decreases LDL by 60%
51
Drugs best at decreasing TG
Fibrates and Niacin
52
Drugs used to illustrate the "steal" phenomenon in pharmacologic/nuclear medicine stress testing
IV Dipyridamole or Adenosine
53
Drug that increases HR and contractile force for pharmacologic stress testing
Dobutamine
54
Pre-hospital management of STEMI
- ASA - Continuous cardiac monitoring - oxygen - sublingual NTG
55
Emergency department management of STEMI
- ASA (if not already given) - cardiac monitoring - MONA (morphine, oxygen, NTG, ASA) - Beta blockers - Heparin
56
Time deadline for reperfusion therapy
< 12 hrs from onset of symptoms
57
Time deadline for fibrinolytic therapy
< 30 minutes from hospital arrival
58
Drugs to give for aortic dissection?
IV NTG sodium nitroprusside BBs (reduces LV contractile force) vasodilators (lowers SBP)