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Paramedic Drug Week 10 > Cardizem > Flashcards

Cardizem Flashcards

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1
Q

Diltiazem Hydrochloride
(Cardizem, Lyo-Ject)
Class

A

Calcium channel blocker

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2
Q

Diltiazem Hydrochloride
(Cardizem, Lyo-Ject)
Mechanism of Action

A

Block influx of calcium ions into cardiac muscle
Prevents spasm of coronary arteries
Decreases the rate of ventricular response.
Arterial and venous vasodilator.
Reduces preload and afterload.
Reduces myocardial oxygen demand.

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3
Q

Diltiazem Hydrochloride
(Cardizem, Lyo-Ject)
Indications

A

Control of rapid ventricular rates due to atrial flutter, atrial fibrillation, and re-entry SVT; angina pectoris.

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4
Q

Diltiazem Hydrochloride
(Cardizem, Lyo-Ject)
Contraindications

A

Hypotension, conduction system disturbances (sick sinus syndrome, second- or third-degree AV block), cardiogenic shock, wide-complex tachycardias, poison/drug-induced tachycardia

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5
Q

Diltiazem Hydrochloride
(Cardizem, Lyo-Ject)
Adverse Reactions

A

Bradycardia, second- or third-degree AV block, chest pain, CHF, syncope, V-fib, V-tach, nausea, vomiting, dizziness, dry mouth, dyspnea, and headache.

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6
Q

Diltiazem Hydrochloride
(Cardizem, Lyo-Ject)
Drug Interactions

A

Caution in patients using medications that affect cardiac contractility (inotropic).
In general should not be used in patients taking beta-blockers.

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7
Q

Diltiazem Hydrochloride
(Cardizem, Lyo-Ject)
Dosage and Administration
Adult

A

Initial bolus: 0.25 mg/kg (average does of 15 – 20 mg) IV over 2 minutes. If inadequate response, may repeat bolus in 15 minutes: 0.35 mg/kg (average dose 20 – 25 mg) IV over 2 minutes. Maintenance infusion of 5 – 15 mg/hr

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8
Q

Diltiazem Hydrochloride
(Cardizem, Lyo-Ject)
Dosage and Administration
Pediatric

A

Not recommended

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9
Q

Diltiazem Hydrochloride
(Cardizem, Lyo-Ject)
Onset

A

Onset: 2 – 5 minutes IV

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10
Q

Diltiazem Hydrochloride
(Cardizem, Lyo-Ject)
Peak Effect

A

Peak effect: Varies

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11
Q

Diltiazem Hydrochloride
(Cardizem, Lyo-Ject)
Duration

A

Duration: 1 -3 hours

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12
Q

Diltiazem Hydrochloride
(Cardizem, Lyo-Ject)
Special considerations

A

Use with caution in patients with renal or hepatic dysfunction. PVCs may be noted at the time of conversion of PSVT to sinus rhythm.

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Paramedic Drug Week 10 (3 decks)

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