Cardiovasular Flashcards

1
Q

SA and AV nodes are supplied by

A

RCA

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2
Q

what branch of blood vessel supply post 1/3 of interventricular septum, posterior walls of ventricls, and posteromedial papillary muscle?

A

post. descending interventricular artery (PDA)

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3
Q

Rt. common cardinal vein and Rt. ant cardinal vein give rise to what structure in the heart?

A

superior vena cava (SVC)

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4
Q

truncus arteriosus gives rise to

A

ascending aorta and pulmonary trunk

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5
Q

coronary sinus is derived from

A

Lt. horn of sinus venosus

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6
Q

what failure leads to patent foramen ovale?

A

failure of septum primum and septum secundum to fuse after birth

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7
Q

when does the heart tube loops establish Lt. to Rt. polarity?

A

4 weeks

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8
Q

what valves are derived from endocardial cushions of outflow tract?

A

aortic/pulmonary

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9
Q

mitral/tricuspid valves are derived from

A

fused endocardial cushions of the AV canal

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10
Q

what path does most commonly occur in the membranous septum?

A

ventricular septal defect (VSD)

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11
Q

explain the characteristic of VSD murmur

A

systolic murmur, holosystolic, harsh-sounding murmur, loudest at tricuspid area

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12
Q

what 2 septums fuse to form membranous interventricular septum?

A
  1. aorticopulmonary septum

2. muscular ventricular septum

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13
Q

what are conotruncal abnormalities? name 3 examples

A

abnormalities in the outflow tract formation

  1. transposition of great vessels
  2. tetralology of fallot
  3. persistent truncus arteriosus
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14
Q

name the sequence of fetal erythropoiesis

A
  1. yolk sac (3-8wk)
  2. liver (6 wk - birth)
  3. spleen (10-28wk)
  4. bone marrow (18 wk to adult)

Young Liver Synthesizes Blood.

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15
Q

what hemoglobin is alpha2 gamma2?

A

fetal hemoglobin (HbF)

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16
Q

why does HbF has higher affinity for O2?

A

due to less avid binding of 2,3 BPG allowing HbF to extract O2 from maternal hemoglobin and across the placenta

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17
Q

location of the lowest oxygenation in fetal circulation?

A

ductus arteriosus, umbilical arteires

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18
Q

name of the remnant of ductus arteriosus?

A

ligamentum arteriosum

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19
Q

2 things that keep the PDA open?

A

prostaglandins E1 and E2

20
Q

benign capillary hemangioma of infancy?

A

strawbery hemangioma (it blanches)

21
Q

what particular vascular tumor is associated with vinyl chloride (PVC) and arsenic?

A

hepatic angiosarcoma

22
Q

what vascular tumor is associated with radiation therapy and chronic postmastectomy lymphedema?

A

angiosarcoma

23
Q

what is the problem with angiosarcoma?

A

very aggressive and difficult to resect due to delay in diagnosis

24
Q

benign capillary hemangioma of the elderly?

A

cherry hemangioma

25
does cherry hemangioma regress?
no
26
what is the name of the vascular tumor that is benign, painful, red-blue tumor under fingernails?
glomus tumor
27
where does the glomus tumor come from?
modified smooth muscle cells of the thermoregulatory glomus body
28
what is the most commonly occurred endothelial malignancy?
kaposi sarcoma
29
does kaposi sarcoma blanch?
no, b/c it is not a vascular tumor (blood is not in the blood vessel)
30
does hemangioma blanch?
yes, b/c the blood is in the blood vessel
31
what vascular tumor is associated with trauma and pregnancy?
pyogenic granuloma
32
how is kaposi sarcoma diff from bacillary angiomatosis?
lymphocytic infiltration
33
define aortic dissection
longitudinal intimal tear forming a false lumen (must have pre-existing weakness of the media due to HTN)
34
what are the 2 types of aortic dissection?
1. type A (proximal) --> involves ascending aorta | 2. type B (distal) --> involves descending aorta
35
which type of aortic dissection can be treated with surgery?
type A (proximal)
36
treatment for type B AD?
beta blockers then vasodilators
37
what is the consequence of aortic dissection?
rupture --> pericardial tamponade
38
triads of cardiac tamponade?
1. hypotension 2. distended neck veins 3. distant heart sound
39
define pulsus paradoxus
dec in amplitude of systolic BP by more than 10 mmHg during inspiration
40
name all the paths associated with pulsus paradoxus?
cardiac tamponade, asthma, obstructive sleep apnea, pericarditis, croup
41
path associated with lack of aorticopulmonary septum formation?
persistent truncus arteriosus
42
2 paths associated with 22q11 syndromes?
truncus arteriosus, tetralogy of fallot
43
cardio path associated with Williams syndrome?
supravalvular aortic stenosis
44
umbilical vein becomes what?
ligamentum teres hepatis (falciform ligament)
45
what becomes medial umbilical ligaments?
umbilical arteries
46
what becomes mediaN umbilical ligament?
allaNtois --> urachus