Cardiovasular Flashcards

1
Q

SA and AV nodes are supplied by

A

RCA

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2
Q

what branch of blood vessel supply post 1/3 of interventricular septum, posterior walls of ventricls, and posteromedial papillary muscle?

A

post. descending interventricular artery (PDA)

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3
Q

Rt. common cardinal vein and Rt. ant cardinal vein give rise to what structure in the heart?

A

superior vena cava (SVC)

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4
Q

truncus arteriosus gives rise to

A

ascending aorta and pulmonary trunk

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5
Q

coronary sinus is derived from

A

Lt. horn of sinus venosus

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6
Q

what failure leads to patent foramen ovale?

A

failure of septum primum and septum secundum to fuse after birth

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7
Q

when does the heart tube loops establish Lt. to Rt. polarity?

A

4 weeks

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8
Q

what valves are derived from endocardial cushions of outflow tract?

A

aortic/pulmonary

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9
Q

mitral/tricuspid valves are derived from

A

fused endocardial cushions of the AV canal

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10
Q

what path does most commonly occur in the membranous septum?

A

ventricular septal defect (VSD)

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11
Q

explain the characteristic of VSD murmur

A

systolic murmur, holosystolic, harsh-sounding murmur, loudest at tricuspid area

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12
Q

what 2 septums fuse to form membranous interventricular septum?

A
  1. aorticopulmonary septum

2. muscular ventricular septum

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13
Q

what are conotruncal abnormalities? name 3 examples

A

abnormalities in the outflow tract formation

  1. transposition of great vessels
  2. tetralology of fallot
  3. persistent truncus arteriosus
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14
Q

name the sequence of fetal erythropoiesis

A
  1. yolk sac (3-8wk)
  2. liver (6 wk - birth)
  3. spleen (10-28wk)
  4. bone marrow (18 wk to adult)

Young Liver Synthesizes Blood.

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15
Q

what hemoglobin is alpha2 gamma2?

A

fetal hemoglobin (HbF)

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16
Q

why does HbF has higher affinity for O2?

A

due to less avid binding of 2,3 BPG allowing HbF to extract O2 from maternal hemoglobin and across the placenta

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17
Q

location of the lowest oxygenation in fetal circulation?

A

ductus arteriosus, umbilical arteires

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18
Q

name of the remnant of ductus arteriosus?

A

ligamentum arteriosum

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19
Q

2 things that keep the PDA open?

A

prostaglandins E1 and E2

20
Q

benign capillary hemangioma of infancy?

A

strawbery hemangioma (it blanches)

21
Q

what particular vascular tumor is associated with vinyl chloride (PVC) and arsenic?

A

hepatic angiosarcoma

22
Q

what vascular tumor is associated with radiation therapy and chronic postmastectomy lymphedema?

A

angiosarcoma

23
Q

what is the problem with angiosarcoma?

A

very aggressive and difficult to resect due to delay in diagnosis

24
Q

benign capillary hemangioma of the elderly?

A

cherry hemangioma

25
Q

does cherry hemangioma regress?

A

no

26
Q

what is the name of the vascular tumor that is benign, painful, red-blue tumor under fingernails?

A

glomus tumor

27
Q

where does the glomus tumor come from?

A

modified smooth muscle cells of the thermoregulatory glomus body

28
Q

what is the most commonly occurred endothelial malignancy?

A

kaposi sarcoma

29
Q

does kaposi sarcoma blanch?

A

no, b/c it is not a vascular tumor (blood is not in the blood vessel)

30
Q

does hemangioma blanch?

A

yes, b/c the blood is in the blood vessel

31
Q

what vascular tumor is associated with trauma and pregnancy?

A

pyogenic granuloma

32
Q

how is kaposi sarcoma diff from bacillary angiomatosis?

A

lymphocytic infiltration

33
Q

define aortic dissection

A

longitudinal intimal tear forming a false lumen (must have pre-existing weakness of the media due to HTN)

34
Q

what are the 2 types of aortic dissection?

A
  1. type A (proximal) –> involves ascending aorta

2. type B (distal) –> involves descending aorta

35
Q

which type of aortic dissection can be treated with surgery?

A

type A (proximal)

36
Q

treatment for type B AD?

A

beta blockers then vasodilators

37
Q

what is the consequence of aortic dissection?

A

rupture –> pericardial tamponade

38
Q

triads of cardiac tamponade?

A
  1. hypotension
  2. distended neck veins
  3. distant heart sound
39
Q

define pulsus paradoxus

A

dec in amplitude of systolic BP by more than 10 mmHg during inspiration

40
Q

name all the paths associated with pulsus paradoxus?

A

cardiac tamponade, asthma, obstructive sleep apnea, pericarditis, croup

41
Q

path associated with lack of aorticopulmonary septum formation?

A

persistent truncus arteriosus

42
Q

2 paths associated with 22q11 syndromes?

A

truncus arteriosus, tetralogy of fallot

43
Q

cardio path associated with Williams syndrome?

A

supravalvular aortic stenosis

44
Q

umbilical vein becomes what?

A

ligamentum teres hepatis (falciform ligament)

45
Q

what becomes medial umbilical ligaments?

A

umbilical arteries

46
Q

what becomes mediaN umbilical ligament?

A

allaNtois –> urachus