Cardiovascular system and blood-Anatomy (lectures 4 to 7) Flashcards
What makes up the cardiovascular system?
Blood Vascular System and Lymphatic (Vascular) System
Lymphatic (Vascular) System
Open-entry drainage system, one-way system
Blood Vascular System
Closed supply and drainage system, continuous loop
General Principles of Organisation of
Cardiovascular system
-supply side: Arteries are only supply path, Major arteries situated to avoid damage, Important structures often receive supply from two sources
(two separate arteries), Arteries change their name at each major branch.
-Exchange network: Capillaries of varying degrees of permeability (Continuous, Fenestrated, Sinusoidal)
-Drainage: Deep veins, Superficial veins, Lymphatics
Heart structure
Blunt, cone shaped, Pointed end - Apex, Broad end - Base
Venous return to the Atria of the Heart-thin walled (receiving) chambers
Right atrium receives: superior vena cava, inferior vena cava, coronary sinus (deoxygenated blood)
Left atrium receives: four pulmonary veins (oxygenated blood)
Heart structure
-Layers of the heart wall: Endocardium (Squamous epithelium (endothelium), Loose irregular fibrous connective tissue (FCT)), Myocardium, Epicardium
-Pericardium (outer wall of heart (like a bag)
Heart wall
-Pericardium: Fibrous pericardium, Parietal layer of serous pericardium, Pericardial cavity
-Epicardium (visceral serous pericardium, loose irregular FCT (adipose), blood vessels)
-Myocardium
-Endocardium
Atrioventricular (AV) valves
Function: Prevent blood returning to atria during ventricular contraction.
Right side - tricuspid valve.
Left side - bicuspid (mitral) valve.
Semilunar valves
Function: Prevent blood returning to ventricles during filling (diastole).
Right side - Pulmonary (semilunar) valve, 3 cusps.
Left side - Aortic (semilunar) valve, 3 cusps.
Pushed open as blood flows out of heart.
Close as blood starts to backflow.
Myocardium
Cardiac muscle
Features of both smooth & skeletal muscle as
well as cardiac muscle specific specialisations.
Function: Beating of the heart
Cardiac Muscle Cell Structure
Striated
Short, branched cells.
One (sometimes 2) nuclei / cell.
Central (oval shaped), nucleus.
Cytoplasmic organelles packed at poles of nucleus.
Interconnected with neighboring cells via intercalated disks (ICDs)
Cardiac Muscle, Intercalated disks
Adhesion belts (linking actin to actin) (Vertical portion)
Desmosomes (linking cytokeratin with cytokeratin).
Gap junction (electrochemical communication) (Horizontal portion)
Conduction System of the Heart
Its actions greatly increase efficiency of heart pumping.
System responsible for co-ordination of heart contraction and of atrioventricular valve action.
Autonomic nerves alter rate of conduction impulse generation.