Cardiovascular system Flashcards

1
Q

Explain the role of;

  1. Chemoreceptors
  2. Proprioceptors
  3. Baroreceptors
A

Chemoreceptors
1. Located In muscles, aorta and carotid arteries
2. Detects an Increase in Carbon dioxide (C02)
and a decrease in pH levels (Blood acidity)
3. Sends a signal to the sympathetic nervous system, which sends a signal to the Cardiac Control Centre. (The CCC then sends a signal via the sympathetic nerve to the Sino atrio node to increase Heart Rate).

Proprioceptors
1. Are located In muscles/Tendons/spindles/joint receptors
2. Increase in motor activity sends a signal to the CCC to Increase HR and SV

Baroreceptors
1. Located in Aorta and carotid arteries.
2. An increase or decrease in Blood pressure signals the medulla in the brain.

Increased blood pressure decreases the HR.

Decreased blood pressure increases the HR.

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2
Q

Suggest how improved fitness, brought about by regular training, may benefit the health of an individual.

[2 marks]

A

Award one mark for each of the following points (max 2 marks):

  • Reduces weight / fat / less obesity / reduced cholesterol
  • Strengthens heart / reduce chance of heart attack / coronary risk factors
  • Improved social / mental / physical well-being
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3
Q

Describe how an increase in carbon dioxide in the blood during exercise would lead to an increased breathing rate.

[3 marks]

A

*   Increased blood acidity/decreased blood pH levels. (1)

*   Detected by chemoreceptors. (1)

*   Impulse sent to the respiratory centre/medulla. (1)

*   Increased impulses to respiratory muscles to contract faster. (1)

Accept named respiratory muscles including diaphragm/intercostal muscles/scalene/ sternocleidomastoid/pectorals/abdominals.

Accept any other appropriate description of how an increase in carbon dioxide in the blood during exercise would lead to an increased breathing rate.

Max 3 marks

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4
Q

(1) A high percentage of body fat can have a negative impact on health and fitness. Define the terms health and fitness.

(2) Other than diet, explain how two different lifestyle choices can have a negative impact on health.

A

(i) A Health – social, mental and physical well-being and not merely the absence of disease.

B Fitness – the ability to carry out everyday tasks without undue fatigue/the ability to the meet/cope with the demands of the environment

(ii) A Smoking – reduces lung/oxygen transport capacity/causes lung cancer/heart disease/stroke

Accept any named disease.

B (Lack of) exercise – obesity/reduced flexibility/strength/mobility issues /increased blood pressure/heart disease/diabetes

Also accept inactivity or equivalents for exercise.

C Alcohol/drugs – damages liver/heart disease/cancer/diabetes/depression

D Work-life balance – stress

E (Lack of) sleep – fatigue/stress

F Over-training – long term injury

Do not accept answers relating to diet, eg supplements or fitness

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5
Q

Performers in team games such as netball need to be suitably prepared to meet the demands of the game.

(i) In order to play netball effectively, performers need to be fit. What do you understand by the term fitness? (1 mark)

(ii) Discuss whether you must be healthy in order to be fit. (2 marks)

A

(i) Fitness- Ability to meet everyday demands of the environment to cope.

(ii) Healthy – social, mental and physical well-being. E.g the absence of loneliness, disease or mental illness like depression.

An athlete may be healthy as they do not have cancer or depression. However, they may be unfit as they lack cardiovascular endurance. For example they may be a PE teacher who is unable to deliver a lesson without becoming fatigued due to their poor Cardiovascular endurance.

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6
Q

Describe how the cardiac conduction system causes the heart to contract.

[3 marks]

A

*   The sino-atrial node (SAN) (the pace maker of the heart) sends an impulse/electrical signal through the walls of the atria (1)

*   Spreads as a wave of excitation (1)

*   This causes atrial systole / atria contract (1)

*   The impulse then passes to the atrio-ventricular node (AVN), (which delays the impulse (for around 0.1 seconds, enabling atria to fully empty) (1)

*   The impulse passes down the Bundle of His (in the septum of the heart), to the Purkinje fibres in the (walls of) the ventricles (1)

*   Ventricular systole then occurs / ventricles contract (1).

Students must refer to the system in order.

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7
Q

Outline two ways an active lifestyle can reduce the risk of heart disease.

[2 marks]

A

*   Decrease in cholesterol/Low density Lipoprotein/fat in coronary arteries (1)

*   Lower blood pressure (1)

*   Stronger heart/cardiac hypertrophy/higher stroke volume (1)

Do not accept decrease in HDL.

Accept any other appropriate outline of how an active lifestyle can reduce the risk of heart disease.

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8
Q

Describe how heart disease can result in a heart attack. [ 2 marks]

A

*  Hardening of coronary arteries/build-up of plaque/cholesterol/fat in the coronary arteries/atherosclerosis/arteriosclerosis (1)
*  Causes blockage/blood clot (1)
*  Limiting the supply of oxygen to the heart/angina (1)
Accept any other appropriate description of how heart disease can result in a heart attack.

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9
Q

Stateonepositive effect that high density lipoproteins have on the body.

(Total 1 mark)

A

*  Remove excess cholesterol (1)
*  Transport excess cholesterol to the liver (1)
*  Protect the artery walls against LDL cholesterol / an anti-inflammatory effect (1)
*  Help protect blood cells and important chemical messengers in the blood from being broken down by the liver / positive anti-oxidant effect (1)
*  Reduce the risk of heart disease (1)
Accept first answer only.
Accept any other positive effect that high density lipoproteins have on the body.

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10
Q
  1. What can cause a stroke
  2. What can cause Coronary heart disease
A
  1. A stroke occurs when the blood supply is cut off to the brain. This can lead to a disability or death.
  2. CHD occurs when arteries harden and narrow due to a build up of fatty cells. This process is called atherosclerosis.
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11
Q

Describe what is meant by blood pressure and explain the different between Diastollic and Systollic pressure

A

Firstly, blood pressure refers to the force exerted by the blood against the wall of the blood vessels. This can be referred to by blood flow x resistance.

When the ventricles contract SYSTOLIC PRESSURE forces blood from the heart.

When the ventricles relax DIASTOLIC PRESSURE allows blood to enter the heart.

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12
Q

Explain the difference between LDL (Low density Lipoprotein) and HLD (High denisty Lipoprotein) cholesterol

A

There are two types of cholesterol. Low density lipoprotein (LDL) and High density lipoprotein (HDL).

LDL is classed as bad cholesterol as it transports cholesterol/plaque in the blood to the tissues. This increases the chance of CHD.

HDL is classed as good cholesterol as it transports cholesterol in the blood to the liver, where it is broken down.

HDL can reduce the chance of coronary heart disease, heart attack and kidney failure and protect the artery walls against LDL.

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13
Q

Explain how the heart controls the rate at which it beats.

[4 marks]

A
  1. The heart generates it’s own electrical and nerve impulse, meaning it myogenic.
  2. The Sino atrial node generates an electrical impulse (like a mexican wave) to cause the heart to beat (The SAN is often referrred to as the pacemaker).
  3. The SAN causes systole which is when the heart contracts
  4. The Atrio ventricular (AVN) node recieves the eltrical impulse for the SAN, The AVN causes a slight 0.1 second delay to allow the atria to contract, which allows a diastollic contraction (when the heart fills with blood).
  5. The eletical impulse then passes through the bundle of HIS, which is a collection of cardiac cells that spread to two bundle branches.
  6. The elctrical impulse then moves into Purkinje Fibres, these small muscle fibres spread to the ventricles, causing them to contract.
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14
Q

Explain the role of the atrioventricular node in the cardiac conduction system.

[3 marks]

A

*   Receives impulse from sinoatrial node (1)

*   Delays (transmission of) impulse (1)

*   To allow ventricular filling/enable the atria to fully contract (1)

*   Sends impulse down septum/through bundle of His/to purkinje fibres (1)

Accept any other appropriate explanation of the role of the atrioventricular node in the cardiac conduction system.

Max 3 marks

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15
Q

Describe the role of the sympathetic and parasympathetic nervous systems in the regulation of heart rate.

[3 marks]

A

*   Medulla/cardiac control centre sends impulse to the Sino-atrial node (SAN)/pacemaker. (1)

*   Sympathetic nervous system increases heart rate. (1)

*   Sympathetic impulses travel down the sympathetic/accelerator nerve. (1)

*   Parasympathetic nervous system decreases heart rate. (1)

*   Parasympathetic nervous systems travel down the vagus nerve. (1)

Accept any other appropriate description the role of the sympathetic and parasympathetic nervous systems in the regulation of heart rate.

Maximum 3 marks

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16
Q

Heart rate is controlled by the cardiac conduction system.

Which one of the following is the order of the cardiac conduction system?

[1 mark]

A

Atrioventricular node, sinoatrial node, bundle of His, Purkinje fibres

B

Atrioventricular node, sinoatrial node, Purkinje fibres, bundle of His

C

Sinoatrial node, atrioventricular node, bundle of His, Purkinjie fibres

D

Sinoatrial node, atrioventricular node, Purkinje fibres, bundle of His

A

C

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17
Q

During a game of football, a player’s heart rate will vary.

Explain how changes in the acidity of the blood cause the heart rate to increase during a game of football.

[4 marks]

A

Blood’s acidity increases / pH lowers.

Caused by more carbon dioxide being produced.

This is detected by chemoreceptors (must include key term detect)

Nerve messages are sent to the medulla (oblongata) / cardiac (control) centre.

Sympathetic nervous impulses are sent.
To the Sino-Atrio node / SAN/SA node.

Decrease in parasympathetic / vagus nerve impulses.

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18
Q

During a game, a player’s work rate will vary. Describe how the ‘parasympathetic’ and the ‘sympathetic’ nerve pathways control heart rate during a game.

[3 marks]

A
  1. Controlled by medulla oblongata/ cardiac centre.
  2. Sympathetic pathway increases heart rate; due to the release of adrenaline. A signal is sent to SAN to increase the frequency of eletical impulse, this causes an increase in stroke volume.
  3. Parasympathetic pathway decreases Heart rate due to the release of Acetylcholine. A signal is sent via the vargus nerve.
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19
Q

If endurance events take place in warm conditions, cardiovascular drift can occur.
Analyse how cardiovascular drift may result in lower levels of performance.

[3 marks]

A

*  Athletes will sweat reducing the plasma volume of blood. (1)
*  Blood becomes more viscous/thicker which reduces venous return. (1)
*  Due toStarling’s lawstroke volume/ejection fraction will decrease. (1)
*  Asstroke volume/ejection fractiondecreasesheart rateincreases to maintain/increasecardiac output. (1)
*  Having a higher heart rate at a lower than normal intensity increases the athlete’s rate of perceived effort/the performer mentally thinks they are working harder than they are. (1)
Accept any other appropriate analysis of how cardiovascular drift may result in lower levels of performance.

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20
Q

Explain how rising levels of carbon dioxide cause an increase in cardiac output.

[4 marks]

A
  1. Increases acidity / hydrogen ion concentration / lowers pH / (in blood);
  2. Detected by chemoreceptors;
  3. Impulses / information to cardiac centre / medulla (oblongata);
  4. Increased stimulation of sympathetic nerve / decreased stimulation of
    parasympathetic / vagus nerve
  5. Adrenaline / nor-adrenaline
  6. To S.A.N. / S.A node / sino-atrial node
  7. Increase in heart rate
  8. Increase in venous return
  9. Increase in stroke volume / ejection fraction
  10. Starlings Law of the heart.
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21
Q

Explain the cause and effect of high blood pressure

[3 marks]

A
  1. Firstly, blood pressure refers to the force exerted by the blood against the wall of the blood vessels. This can be referred to by blood flow x resistance.
  2. When the ventricles contract SYSTOLIC PRESSURE forces blood from the heart.
  3. When the ventricles relax DIASTOLIC PRESSURE allows blood to enter the heart.
  4. High blood pressure puts strain on the arteries and can cause a heart attack, heart failure, kidney disease or stroke.
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22
Q

(i) Explain the term anticipatory rise.

[1 mark]

(ii) Neural control of heart rate involves the autonomic nervous system.

Identify and explain the role of different receptors involved in increasing heart rate.

[3 marks]

A

(i) Increase in heart rate prior to exercise caused by (the release) of adrenaline.

(ii) Chemoreceptors – detect increase in blood acidity / decrease in pH / increase in CO2 / increase in Hydrogen ion concentration / H+

Proprioceptors / mechanoreceptors – detect movement / muscular contractions

Baroreceptors – detect decrease in blood pressure

Impulses sent to cardiac control centre / medulla (oblongata)

Increase in impulses to the SA node via the sympathetic nervous system / cardiac accelerator nerve

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23
Q

If an athlete performs a continuous exercise session lasting 45 minutes at a sub-maximal pace, cardiovascular drift will occur.
Explain the term cardiovascular drift.

[3 marks]

A

AIncrease in heart ratedue to / anda decrease in stroke volume / ejection fraction.
donotaccept abbreviations – SV, Q, HR
BOccurs after 10 minutes.
CWarm environmental conditions.
DCaused by a reduction of fluid in the blood / plasma / blood volume / increase in sweating/ blood more viscous.
EVenous return decreases / blood pumped back to heart decreases / reduced atrial filling.
FAims tocool the body(by maintaining cardiac output).
reason for increase in cardiac output explained.

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24
Q

When a performer is running, blood is redirected to the working muscles.
Explain how this redistribution of blood is achieved.

[5 marks]

A
  1. During exercise the acidity of the blood changes due to an increase in carbon dioxide & lactic acid, this causes a drop in Blood PH.
  2. The drop of PH levels causes oxygen to disassociate from heamoglobin (Bohr Shift).
  3. The chemoreceptors sense this chemical change and the nerve cells transmit this information to the medulla oblongota (vasomotor centre).
  4. The medulla oblongota sends sympathetic nerve impulses which releases adrenaline.
  5. The increased levels of Adrenaline cause the SAN to increase in frequence to increase one’s heartbeat and cardiac output.
  6. The increase in heartbeat allows more oxygenated blood to be directed to the working skeletal muscles (Vascular stunt mechanism).
  7. The vasomotor centre controls the distribution of blood. Vasodilation occurs to increase the diameter of the blood vessels to facilitate more blood being sent to working muscles. For example the biceps when performing chin ups.
  8. Vasoconstriction occurs to decrease the size of the diameter of the blood vessels to restrict blood flow to organs such as the liver and kidneys, as they are not essential in satisfying the demands of exercise.
25
Q

The table below represents heart rate and stroke volume for an untrained performer as intensity of exercise increases.

Calculate cardiac output for the untrained performer at point D in the table above.

A- SV =85ml Hr=70BMP
B- SV=90ml Hr=90BPM
C- SV=100ml Hr=95BPM
D-SV=100m HR= 100BPM
[1 mark]

A

Cardiac output = 120 x 100
 = 12000 ml / min / 12 L / min

26
Q

The table below represents heart rate and stroke volume for an untrained performer as intensity of exercise increases.

Explain how and why the components of cardiac output differ for a trained performer at point A.

A

*  Trained athlete would have a lower resting heart rate of below 60 bpm / bradycardia (1)
*  The trained athlete has a higher resting stroke volume (more blood ejected per beat) (1)
*  Regular training of trained performer leads to cardiac hypertrophy (1)
*  This means a trained performer will have stronger heart / more forceful contraction (1).

27
Q

Paul and Mark are both 20 years old. Paul does no exercise. Mark is a cross country runner who trains three times a week.

How would maximal cardiac output differ between Paul and Mark? Justify your answer.

(Total 3 marks)

A

How (AO2)
*  Mark’s maximal cardiac output would be higher (1)
Why (AO3) (sub max 2 marks)
*  Mark’s cardiac output would be higher due to greater maximum stroke volume (1)
*  This is due to Paul and Mark having the same maximum heart rate (1)
*  Mark has a greater stroke volume due to cardiac hypertrophy/increased blood volume / any other adaptation to the heart (1)

28
Q

What’s going on at each letter ?

What type of exercise is happening on each graph?

[2 Marks]

A

A= Anticipatory rise (caused by adrenaline)

B= Sharp rise in heart rate due to anaerobic work

C= Steady state as the athlete is able to meet the oxygen demand with the oxygen supply

D=Exercise has stopped so heart rate decreases

E=Slow recovery as heart rate remains elevated to remove waste products like lactic acid [EPOC]

29
Q

Performers will often use running as part of their training programme. Both heart rate and stroke volume increase when running.
Use ‘Starling’s law of the heart’ to explain how stroke volume increases when running.
[3 marks]

A

Increased venous return
not simply more blood back to heart
Greater diastolic filling / heart fills with more blood;
Cardiac muscle stretched / elastic;
Greater / stronger / more powerful force of contraction / contractility;Increased ejection fraction / greater percentage of blood ejected.
not increase stroke volume – in question

30
Q

Q5. Explain the role of adrenaline on heart rate prior to and during a 400 m race.
(Total 3 marks)

A

A. Anticipatory rise happens prior to the race.
Has to be explained in correct context prior to the race
B. Maintains increased heart rate during race.
C. (Adrenaline) to the sino-atrial / SA node.
D. Increased activity / firing at the SA node.

31
Q

Explain three long term effects of exercise in relation to the Cardiovascular system [3 marks]

A

Change in body shapeFat is burned as a consequence of exercise, whilst simultaneously muscles increase in size due to hyper trophy.

Decrease in resting Heart rate (Bradycardia)Bradycardia occurs as the heart increases in size it is able to circulate a greater volume of blood. Therefore, oxygenated blood is circulated more efficiently with each stroke.

Increase in Heart size (Hypertrophy)The heart consists of Cardiac muscle and increases in size as a consequence of Hypertrophy.

Increase number of capillaries in muscles = more efficient oxygen delivery to muscles.

Increase in resting stroke volume – more typical in endurance athletes

Increase in blood volume = increase in red blood cells to carry more oxygen

32
Q
A

D

33
Q

In response to exercise why does Stroke volume initially increase, then level out, before slightly decreasing? [2 marks]

A

1.Stroke volume increases to provide oxygenated blood to the working muscles, in response to the demands of exercise.

  1. Stroke volume will plateau once the athlete is operating at maximum intensity.

3.Stroke volume decreases slightly due to a shortened diastolic phase. Meaning the ventricles do not have as much time to full up with blood before they contract.

34
Q

The graph below shows the cardiac output, pulse rate and stroke volume of an athlete exercising in a warm environment for 45 minutes.

Consider the effect of prolonged exercise in a warm environment on cardiac output and its components. Refer to the graph in your answer. [3 marks]

A

AO2 (sub max 2 marks)
*  Cardiac output increases during prolonged exercise (1)
*  This is because heart rate gradually increases to compensate for a reduction / decrease in stroke volume (1)
*  This is known as cardiovascular drift (1)

AO3
*  Stroke volume decreases during prolonged exercise in a warm environment because of the fluid lost from plasma (1)
*  Cardiac output needs to increase during prolonged exercise in a warm environment to cool the body and to create energy (1)
Accept other appropriate explanations of the effect of prolonged exercise in a warm environment on cardiac output and its components.

35
Q

Explain the two types of circulation

[2 marks]

A

There are two types of circulation

Pulmonary- Deoxygenated blood from the heart to the lungs and back to the heart.

Systemic- Oxygenated blood from the heart to the body and deoxygenated blood from the body to the heart.

36
Q

Identify two features of the structure of arteries. Explain how each feature helps the arteries to perform their function.

[total 4 marks]

A

Feature AO1 (sub-max 2 marks)

*   Small lumen (1)

*   Thick muscular walls (1)

Function AO2 (sub-max 2 marks)

*   Small lumen allows blood to travel quickly away from the heart (1)

*   Thick muscular walls allow blood to travel under high pressure (1)

37
Q

Identify two features of the structure of veins. Explain how each feature helps the Veins to perform their function.

[total 4 marks]

A

Feature AO1 (sub-max 2 marks)

*   large/wide lumen (1)

*   Veins have valves (1)

Function AO2 (sub-max 2 marks)

*   large/wide lumen allows large amounts of deoxygenated blood to travel back to the heart (venous return) (1)

*  Veins have valves to prohibit blood flowing backwards (1)

38
Q

Identify one feature of the structure of capillaries. Explain how this feature helps the capillaries to perform their function.

[total 2 marks]

A

Feature AO1

*   One cell thick (1)

Function AO2

*  Capillaries facilitate diffusion which is the exchange of molecules between the blood and the body’s cells. Allowing O2 and CO2 to diffuse between tissues

39
Q

Explain the 2 main factors that influence blood pressure:

A

Cardiac output – the volume of blood flowing into the system from the left ventricle.

Resistance to the blood flow – could be viscosity of the blood, cholesterol levels and blood vessel length or radius.

40
Q

Explain the impact of blood pressure on Venous Return [2 marks]

A

At rest Venous return matches stroke volume. i.e the same amount of blood that enters leaves.

As Starling’s law states if Venous return increases, the heart contracts with more force

When Systolic blood pressure increases so does venous return, when systolic blood pressure decreases so does venous return.

41
Q

What effect does blood pressure have on Aerobic and Anaerobic exercise

A

Aerobic- Systolic pressure INCREASES due to increased cardiac output and demand of oxygen from working muscles.

Diastolic pressure normally remains at a steady state.

Anaerobic- Systolic pressure INCREASES due to increased cardiac output and demand of oxygen from working muscles.

Diastolic pressure also INCREASES but only slightly due to resistance within blood vessels.

42
Q

When starting to exercise venous return will increase. This will result in more blood returning to the right-hand side of the heart.
Describethreemechanisms that support venous return. [3 marks]

A

((Skeletal) muscle pump) – increased contraction of muscles press nearbyveins(to squeeze blood back to the heart) (1).

(Respiratorypump) – increased breathing rate will alter / changepressurein thoracic cavities / area to (assist blood flow back to the heart) (1).

(Suction pump of heart) – more blood pumped out of the heart, so more blood then drawn / forced back (1).

Pocket valves – (located in veins), stop backflow (by closing) and help shunt blood back to heart (1).

Smooth muscle – located in the walls of the veins / involuntary muscle contraction (help to squeeze blood back to heart) (1).

Accept other appropriate descriptions of venous return mechanisms.

43
Q

Analyse how changes in venous return occurring during exercise help performance in aerobic events such as a triathlon.

(Total 8 marks)

A

AO1 Knowledge of venous return mechanisms
Reference to and description of venous return mechanisms:

*  valves – prevent backflow of blood
*  skeletal muscle pump – working muscles contract and compress veins to push blood back towards the heart
*  respiratory pump – increased respiration/changes in pressure in the thorax compress veins to push blood back towards the heart
*  smooth muscle – found in veins and contracts to push blood back towards the heart
*  suction pump of the heart – pulls blood back toward the heart.
*  
AO2 Application to increased venous return during exercise

Changes in venous return during exercise:
*  during exercise increased use of muscles in arms (swimming) and legs (swimming, cycling, running) compresses veins more pushing more blood back to the heart
*  increased breathing rate during exercise causes increased effect of respiratory pump returning more blood to the heart
*  suction pump of the heart increase as the heart beats harder and faster during exercise
*  overall increase in venous return during exercise.
**
AO3 Analysis of reasons why these changes are required to occur**
*  Starling’s law.
*  This causes the heart muscle to stretch more increasing ejection fraction/stroke volume/cardiac output.
*  More blood leaving the heart means more blood sent to the lungs for greater gas exchange (removal of CO2and uptake of O2).
*  More blood to working muscles supplying O2for resynthesis of ATP.
*  The more O2that is supplied the longer the performer can work aerobically for, limiting the production of fatiguing by-products such as lactate.
*  Can work at higher intensities for longer periods of time.
Accept any other appropriate analysis of how changes in venous return, which occur during exercise, allow performance in aerobic events such as a triathlon.

44
Q

Explain the function of:

Plasma

Myoglobin

Mitochondria

A
  1. Plasma is the fluid within our blood
  2. Myoglobin stores oxygen in slow twitch muscle fibres
  3. Mitochondria is the part of the cell where respiration and energy production occurs.
45
Q

Explain the Oxyhaemoglobin disassociation curve, when the athlete is at rest

A
  1. As the partial pressure of oxygen in the lungs is high, haemoglobin almost completely saturates with oxygen, because there’s lots of oxygen in the lungs to attach to haemoglobin.
  2. As haemoglobin moves around the body to tissues, e.g skeletal tissue, the pressure of oxygen begins to decrease.
  3. Due to this pressure change the haemoglobin DISASSOCIATES (releases) oxygen to the tissues, to compensate for the change in pressure.
  4. At rest the haemoglobin will give around 23% of it’s oxygen to the muscles. This is sustainable.
46
Q

Explain what happens to the oxygen disassociate curve due to Bohr’s shift

A
  1. During exercise the curve shifts to the right. This is because the demand for oxygen is greater.

Also, Carbon dioxide levels rise when we exercise which changes the pressure. The drop in pressure of oxygen causes the haemoglobin to DISSASOCIATE all of the oxygen it has.

  1. This phenomenon is known as the Bohr shift and ensures more oxygen is available to the working muscles.
47
Q

What three factors facilitate Bohr’s shift occuring?

A
  1. Increase in (blood / body) temperature- oxygen disassociates from haemoglobin more readily in warmer climates.
  2. Increase in blood carbon dioxide concentration levels (pCO2)- oxygen disassociates from haemoglobin more readily if CO2 levels increase rapidly.
  3. Increase in blood acidity / decrease in pH- more CO2 lowers the acidity (ph) levels in our blood, this drop causes oxygen to disassociate from haemoglobin more readily.
48
Q

Explain the causes of the Bohr shiftandhow it increases oxygen delivery to the working muscles.

[3 marks]

A
  1. Oxygen Dissasociation Curve shifts to right;
  2. Exercise increases body and blood temperature- oxygen disassociates from haemoglobin more readily in warmer climates.
  3. Exercise causes more CO2, this lowers the acidity (ph) levels in our blood, this drop causes oxygen to disassociate from haemoglobin more readily.
  4. More oxygendisassociatesfrom haemoglobin / reduced affinity for oxygen;
49
Q

Where is myoglobin found in the bodyandwhat is its role during exercise? [2 marks]

A

In muscle (Required term is muscle)
Stores / supplies / carries oxygen.

50
Q

Explain the causes of this change to the curveandthe effect that this change has on oxygen delivery to the muscles.

[4 marks]

A

Bohr shift [Required term]
Resulting in less saturation / reduced affinity of haemoglobin with oxygen.

Increase in (blood / body) temperature- oxygen disassociates from haemoglobin more readily in warmer climates.

Increase in blood carbon dioxide concentration (pCO2)- oxygen disassociates from haemoglobin more readily if CO2 levels increase rapidly.

Increase in blood acidity / decrease in pH- more CO2 lowers the acidity (ph) levels in our blood, this drop causes oxygen to disassociate from haemoglobin more readily.

An increase in oxygen release / oxyhaemoglobin dissociation to muscles /muscles receive more O2.

51
Q

When a performer is running, blood is redirected to the working muscles.
Explain how thisredistributionof blood is achieved. [3 marks]

A

Increased metabolic activity / increased carbon dioxide / increased lactic acid / dropin pH in the blood / increased acidity.Detected by chemoreceptors.

Message to medulla / vasomotor control centre.

Autonomic / sympathetic system / adrenaline / noradrenaline produced

.Pre-capillarysphincters / arterioles.

Vasoconstriction– to organs

.Vasodilation– to muscles.

52
Q

Identify and explain the change in blood flow during exercise attwodifferent locations shown in the graph. [4 marks]

A

Identification of location and change
ACoronary vessels –Increasein blood flow
BSkin –Increasein blood flow
CStomach –Decreaseblood flow
Accept first two locations only.
Must state location for points A, B & C.
Explanation
D(coronary vessels) To allow the heart to beat faster/more powerfully
E(skin)Temperature regulation/get rid of heat/cool down
Not to sweat
F(stomach) Blood redistributed away from stomach to where it is needed
Only credit D, E & F if linked to A, B & C.

53
Q

(i)Explain how redistribution of blood occurs during exercise. [3 marks]

(ii)Explain why blood flow to the brain remains the same during restandduring maximum effort. [2 marks]

(iii) Using the table above, explain why performers should not eat immediately before exercise. [2 marks]

A

(i)Increase in CO2levels / acidity / decrease in O2levels / pH / chemoreceptors
Terms need explaining
Movement of joints / tendons / mechanoreceptors / proprioceptors

Vasomotor centre / medulla

Autonomic / sympathetic nervous system / (nor) adrenaline

Pre-capillary sphincters / rings of circular / smooth muscle

Vasodilation to areas needing blood / muscles

Vasoconstriction of areas not needing so much blood / kidneys / liver / gut

(ii)Brain function maintained during exercise
Brain active / working = OK
Oxygen / nutrients required

(iii)During exercise,lessblood goes to the gut / change from 1250 cm3to 375 cm3

Credit use of table to suggest reduced gut blood
But, blood / oxygen needed in gut for digestion of food
‘Unable to digest food’ is incorrect
Less blood / oxygen available to muscles

54
Q

The arterio-venous oxygen difference (a-vO2diff) of the runner in the image above will increase during exercise.

What do you understand by the term a-vO2diffandwhy does it increase during exercise?

[2 marks]

A

Difference between oxygen content of arterial and venous blood / how much O2is extracted and used by muscles;
Sub max 1 mark

Moreoxygen isextractedby the muscles / lungs;
Needs e.g. – accept needed / used by muscles

Oxygen is used / needed for energy / ATP production / respiration.

55
Q

What is meant by the term vascular shunt?

A

Vascular shunting refers to the process that increases blood flow to active areas during exercise, by diverting blood away from inactive areas.

56
Q

Training can increase an athlete’s maximum A-VO2 diff.

Analyse how the body systems adapt to allow this.

[total 3 marks]

A

*   Increased oxygen content in arterial blood due to more red blood cells/haemoglobin/oxygen carrying capacity of the blood (1)

*   Increased gas exchange at the muscle due to increased capillarisation/increases blood supply/surface area (1)

*   Increased gas exchange at the muscle due to more myoglobin which has a greater affinity for oxygen than haemoglobin so pulls more oxygen into muscle/can store more oxygen in muscle (1)

*   Increased gas exchange at the muscle due to larger/more numerous/more efficient mitochondria allowing for more oxygen to be used in a muscle cell so less returned to venous blood (1)

Reference to gas exchange at the muscle only required once for 2nd, 3rd and 4th bullet points.

Accept any other appropriate analysis of how the body systems adapt as a result of training to increase maximum A-VO2 diff.

57
Q

Explain the importance of haemoglobin for a long distance runner.

(total 3 marks)

A

A. Important for oxygen transport in the blood / carries oxygen to the muscles

B. Endurance athletes work aerobically

With oxygen too vague

C. Increased red blood cells, increased aerobic capacity / stamina

D. Delays fatigue / delayed OBLA / prevents build-up of lactic acid

58
Q

Training can increase an athlete’s maximum A-VO2 diff.

Analyse how the body systems adapt to allow this.

[total 3 marks]

A

*   Increased oxygen content in arterial blood due to more red blood cells/haemoglobin/oxygen carrying capacity of the blood (1)

*   Increased gas exchange at the muscle due to increased capillarisation/increases blood supply/surface area (1)

*   Increased gas exchange at the muscle due to more myoglobin which has a greater affinity for oxygen than haemoglobin so pulls more oxygen into muscle/can store more oxygen in muscle (1)

*   Increased gas exchange at the muscle due to larger/more numerous/more efficient mitochondria allowing for more oxygen to be used in a muscle cell so less returned to venous blood (1)

Reference to gas exchange at the muscle only required once for 2nd, 3rd and 4th bullet points.

Accept any other appropriate analysis of how the body systems adapt as a result of training to increase maximum A-VO2 diff.