cardiovascular physiology Flashcards
conducting cells
special cardiocytes that initiate and distribute action potentials in heart
nodes
clusters of autorythmic cells that generate spontaneous action potentials in heart
what happens to a autorhythmic cell in node with unstable resting potential
Na+ leaks in causing gradual depolarization “prepotential.” this causes gated Ca++ channels to open and a influx of Ca++ (depolarization). Ca++ channels closes as K+ voltage channels open causing an efflux of K+ (repolarization)
has unstable resting potential
autorhythmic cells in nodes
how does action potential spread along conducting pathways
through gap junctions at intercalated discs
what nodes does the parasympathetic n.s innervates and what does it do
Acetylcholine slows heart down
what nodes does the sympathetic n.s innervated and what does it do
norepinephrine speeds heart up
why does the pacemaker firing trigger all-or-none contraction of a whole heart
because all cells are connected by gap junctions at the intercalated discs
cardiac muscle anatomy and its functions (5)
gap junctions at intercalated discs (allows ions to move from cell to cell)
desmosomes (anchoring proteins prevent separation of contracting cells)
many mitochondria (cardiac muscle very fatigue resistant)
myofibrils branch
t-tubules trigger release of calcium from sarcoplasmic reticulum