Cardiovascular Pharmacology

Question 1

Adrenergic receptors are divided into two general categories:

Answer 1

alpha and beta

Question 2

The two adrenergic receptor types are broken down into additional subtypes. name them:

Answer 2

alpha 1 and alpha 2

beta 1 and beta 2

Question 3

these receptors are POSTsynaptic:

Answer 3

alpha 1

Question 4

alpha 1 receptors are located in

Answer 4

smooth muscle throughout the body

Question 5

the most important CV effect of alpha 1 stimulation is:

Answer 5

vasoconstriction

Question 6

stimulation of alpha 1 receptors results in what CV changes?

Answer 6

vasoconstriction resulting in:

• increased PVR
• Increased LV Afterload
• increased arterial BP

Question 7

what does stimulation of alpha 1 do to the lungs?

Answer 7

bronchoconstriction

Question 8

alpha 2 receptors are located primarily on the:

Answer 8

PRE-Synaptic nerve terminals

Question 9

which receptors create a negative feedback loop that inhibits further NE release from the neuron?

Answer 9

alpha 2

Question 10

the alpha 2 receptors create a neg fb look that does what?

Answer 10

inhibits additional NE release from the neuron

Question 11

stimulation of alpha 2 receptors in the CNS results in:

Answer 11

sedation and reduction of sympathetic outflow

-resulting in peripheral vasodilation and lower blood pressure