CARDIOVASCULAR OUTCOMES Flashcards

1
Q

BLOOD PRESSURE: def, formula

A

= force of blood against blood vessel

BP = CO (Q) x TPR

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2
Q

CARDIAC OUTPUT: unit, formula, characteristics of each components

A

L/min

= heart rate x stroke volume

Heart rate
- divided in intrinsic (sino-atrial node) & extrinsic (Autonomic nervous system with sympathetic that increases HR & parasympathetic which decreases HR)

Stroke volume
= amount of blood pumping during each cardiac cycle
1) Preload = amount of blood coming to ventricle = venous return → Affects by valves function, muscles pump and posture
2) Afterload = how much resistance ventricle must to overcome squeeze blood → Affects by hypotension, vasoconstriction, stenosis of valves
3) Contractility
→ Affects by exercises & autonomic nervous system (sympathetic increases contractility & parasympathetic decreases contractility)

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3
Q

Total periphery resistance: def & characteristics

A

= friction of blood against blood vessel, as vessel relaxes → resistance decreases

Radius impact → vasoconstriction
→ Affects by hormones (epinephrine), temperature (cold = vasoconstriction), exercise & autonomic nervous system (sympathetic innervates vessel → vasoconstriction // parasympathetic does not innervates vessel)

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4
Q

BP: Invasive method: characteristics, ≠ types, utilization, common sites & risk

A

C: direct

≠: intravascular (tip catheter) & extravascular (arterial line with external transducer)

U: Tube inserted into artery & connected through saline fluid filled line to electrical pressure transducer
→ Catheter line must be free of air. Cannula & tubing stiff & short

CS: brachial, radial & femoral arteries

R: risk of infection

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5
Q

BP: non invasive method: characteristics, intermittent values, continuous waveform & goals

A

C = indirect

IV:
- Auscultatory (Korotkoff method)
- Oscillometric
- Ultrasonic method

CW:
- Tonometric
- Volume clamp (Penaz method)

G: Auscultatory technique, allowing measurement of both systolic & diastolic blood pressure

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6
Q

BP: office: description, traditional manual measurement & automated measurement

A

D: = most commonly basis for hypertension diagnosis & follow-up
- 2-3 office visits at 1-4 week intervals (except of BP>180/110 mmHg)
- Diagnosis confirmed by out of office BP measurement

Traditional manual BP measurement
- Mainstay of BP measurement
- Limited by lack of medical staff
- Inability to assess circadian variation
- Increase white-coat HTN diagnosis leading to over-diagnosis & over-treatment of HTN

Automated office BP measurement
- Decrease white-coat response
- Prediction of cardiovascular events - 3 to 5min period of quiet rest
- 2 to 3 BPs which are averaged

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7
Q

BP: Out of office: home monitoring & ambulatory monitoring

A

Home BP monitoring
- Improved motivation in self-care
- Increase adherence to anti hypertensive medications
- Take at least 2 readings 1 min apart in morning before taking medications & in evening before supper

Ambulatory BP monitoring
- Valuable tool for measuring BP variation day & night in patients with CKD
- Superior to office-measured BP to predicting CKD progression & cardiovascular risk

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8
Q

BP: initial evaluation: description & rules

A

Measure BP in both arms, preferably simultaneously. If consistent ≠ between arms >10 mmHg in repeated measurements, use arm with higher BP
- If ≠ >20 mmHg consider further investigation

Rules
- Back supported
- No talking during & between measurements
- Cuff it fit arm size (small, usual, large)
- Arm bare & resting. Mid-arm at heart level
- Feet flat on floor
- Validated electronic upper arm cuff or manual auscultatory
- Quiet room, comfortable temperature
- No smocking, coffee, exercise for 30 min
- Empty bladder
- Relax for 3-5min
- Take 3 measurements at 1min intervals
- Use average of last 2 measurements

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9
Q

BP: values

A

Tableau

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10
Q

PULSE ASSESSMENT: ≠ types of measure, why?, ≠ values, how measure

A
  • Estimate with pulse
  • Measure with smart watch or electrocardiogram - Measure with belt which measure HR
  • Stethoscope & listen pulse during 1 min at least
  • To assess patient’s pulse rate & to assess strength, regularity & character of pulse
  • Pulse measured at several points in body. Points are where artery situated under skin, where it compressed against bone, allowing us to feel each beat

Tableau for values

  • Wash hands to prevent cross-infection & explain what you are about to do
    If you’ve been active or had stimulant like nicotine/caffeine in last 20min, you’ll need to wait at least 5-20min before taking pulse
    Place tips of first & second finger on inside of patient’s wrist (radial pulse)
    Press gently against pulse
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11
Q

Defintion heart rate

A

= how fast heart contracting at given time (bpm)

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12
Q

Definition pulse rate

A

= Number of times blood flows in arteries

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13
Q

2 ≠ types of cardiovascular measurements

A

Echocardiogram

Electrocardiogram

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14
Q

ECHOCARDIOGRAM: def, how to assess, description

A

D: = type of ultrasound scan to look at heart, structures & nearby blood vessels

To assess
- Myocardial thickness
- Mobility & competence of heart valves
- Dimensions of heart chambers
- Blood flow direction

  • General systolic function: assessment of EF & velocity of myocardial shortening
  • Changes on cardiac chambers: diseases that increase end- diastolic volume
  • Valve insufficiency or stenosis
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15
Q

ELECTROCARDIOGRAM: how work

A

Sensors attached to skin used to detect electrical signals produced by heart each time it beats

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16
Q

ECG: Electrophysiology: 3 ≠ steps & characteristics of each

A

Polarization
- Heart dependent on electrical impulse to beat
- Cardiac cells at rest considered polarized
- Due to charged ions inside cell membrane (sodium & potassium) => more negative charge inside cell membrane & more positive charge outside cell membrane

Depolarization
- Once electrical impulse discharged
- Ions cross cell membrane & cell becomes depolarized
- More positive charge inside cell & more negative charge outside cell => systole, muscles contract

Repolarization
- When cell fully depolarized, it attempts to return to its resting state in process called repolarisation
- Electrical charges in cell reverse & return to normal
- More positive outside cell membrane
- More negative inside cell membrane => diastole, muscles relax

17
Q

≠ phases of cardiac cycle

A

Schema

18
Q

ECG: Einthoven’s triangle: def & ≠ leads

A

= imaginary formation of 3 limb leads in triangle used in electrocardiography, formed by 2 shoulders & pubis

Bipolar Limb Leads (Frontal Plane):
- Lead I
- Lead II - Lead III

Augmented Unipolar Limp Leads (Frontal Plane):
Lead aVR Lead aVL Lead aVF

Unipolar chest leads (Horizontal Plane):
Leads V1, V2, V3 (Posterior Anterior) Leads V4, V5, V6 (Right Left, or Lateral)

19
Q

Signs & direction of vector

A

Electrical vector directed towards exploring electrode in this lead & causes positive deflection (wave)

Electrical vector directed away from exploring electrode in this lead & causes negative deflection (wave)

20
Q

Frontal plane: ≠ leads, name of each & direction of each

A

6 leads = limb leads
aVR, aVL, aVF, I, II & III aVR, aVL, aVF => unipolar I, II & III => bipolar
Read electrical forces in frontal view

Lead aVL:
= augmented vector left
- Positive electrode on left shoulder
- From this view: left atria & circumflex artery

Lead aVR:
= augmented vector right
- Positive electrode on right shoulder
- Not best view because great vessels hide other

Lead aVF:
= augmented vector foot
- Positive electrode on foot
- From this view: ventricle & RCA branches

Lead I:
- Axis goes from shoulder to shoulder
- Negative electrode placed on right shoulder
- Positive electrode placed on left shoulder
- 0° angle of orientation (Lateral wall)
- From this view: left ventricle & lateral part of heart

Lead II:
- Axis goes from right arm to left leg
- Negative electrode on shoulder
- Positive one on leg
- +60° angle of orientation (Inferior wall)
- One of the best way to see heart

Lead III:
- Axis goes from left shoulder to right or left leg
- Negative electrode on left shoulder
- Positive electrode on right or left leg
- +120 degrees angle of orientation (Inferior wall)
- RCA & right ventricle

21
Q

Transverse plane: number & name of leads + characteristics

A

6 leads = precordial leads (chest)
- V1-V6
- Read electrical forces in transverse plane
- Unipolar

22
Q

ECG: 7 steps for analysis

A
  • Step 1: Determine rhythm (regular vs irregular)
  • Step 2: Determine rate
  • Step 3: Evaluate P waves (shape & size)
  • Step 4: Measure PR interval duration
  • Step 5: Measure QRS duration
  • Step 6: Evaluate T wave
  • Step 7: Evaluate ST segment (normal, elevated or depressed)
23
Q

ECG: types of arrhythmia & characteristics

A
  • Sinus tachycardia >100bpm
    Pain, anxiety, hypovolemia, congestive heart failure; severe lung disease
    or sign of hyperthyroidism
  • Sinus bradycardia < 60bpm
    Early stages of acute myocardial infarction, variation in vagal tone,
    intrinsic sinus node disease; it can cause fainting
  • Respiratory sinus arrhythmia
    Variation in heart rate associated with breathing
24
Q

ECG: segments & intervals: ≠ types of segment & description of each

A

PR interval = atrial impulse from SA-AV normal between 0,12-0,22 s

QRS complex = ventricular depolarization normal between 0,06-0,12s

QT interval = time for ventricles to contraction & to full relaxation-normal 0,36-0,44s

ST segment = represents end of ventricular depolarization & beginning of ventricular repolarization
- Become elevated or depressed
- Important to determine STEMI & N-STEMI
- ST-elevation myocardial infarction

P-wave = first component of normal ECG waveform
- Represents atrial depolarization (electrical impulse through atria)
- Immediately after depolarization atria contract
- Precedes QRS complex
- Duration 0.06 to 0.12 s

T-Wave: Represents ventricular repolarization - Location – follows S wave
- Configuration is round & smooth
- Duration 0.10 to 0.25s

25
Q

Respiratory sinus arrhythmia: def & characteristics

A

= heart rate variability in synchrony with respiration
- Normal phenomenon
- Relates to increase in heart rate with inspiration & decrease during expiration

26
Q

ECG patho: ≠ patho

A

AV block
Atrial fibrillation
Atrial flutter
Ventricular fibrillation
Ventricular extrasystole
Ventricular tachycardia
Asystole

27
Q

AV BLOCK: description & common cause

A
  • AVN dysfunction = set of diseases occurring when partial or total block of impulse conduction through AVN: condition known as atrioventricular block
  • Most common cause = idiopathic fibrosis of conduction system Z
28
Q

ATRIAL FIBRILLATION: description & causes

A
  • Loss of coordinated atrial contraction
  • Atrial Rate: 300 – 400/ min
  • Irregular ventricular rate (120-180 bpm)
  • Causes: Hypertension & DM; Lung diseases
  • Reduced cardiac output & formation of atrial thrombus increased risk of mortality
29
Q

ATRIAL FLUTTER: description, frequency

A
  • Results from rapid circuit occurring most commonly in right atrium
  • Frequency: 250-350 bpm
  • Reentrant arrhythmia - reentrant circuit runs around tricuspid valve
  • ECG flutter waves - Regular pace
30
Q

VENTRICULAR FIBRILLATION: description

A
  • Disorganized heart rhythm with multiple excitable areas in ventricles showing large variations in depolarization & repolarization
  • = rapid disorganized ventricular arrhythmia, resulting in no uniform ventricular activation or contraction, no cardiac output & no recordable blood pressure
  • Disorganized & ineffective contraction
  • Impaired pump function (no cardiac output)
31
Q

VENTRICULAR EXTRASYSTOLE: description, types & frequency

A

= extra heartbeats begining in one of heart’s 2 lower pumping chambers (ventricles). Disrupt regular heart rhythm, sometimes causing sensation of fluttering or skipped beat in chest
- Types: parasystolic & coupled
- Frequency: single, couplets, bigeminy, trigeminy
- Important to note that 3 or + consecutive PVCs are classified as ventricular tachycardia

32
Q

VENTRICULAR TACHYCARDIA: description

A

= heart rhythm problem (arrhythmia) caused by irregular electrical signals in lower chambers of heart (ventricles)
- Rapid heartbeat prevents heart chambers from properly filling with blood
- Heart may not be able to pump enough blood to body

33
Q

ASYSTOLE: description

A

= cardiac arrest without electrical activity
- High-quality CPR should be continued with minimal (less than 5 seconds) interruption. CPR should not be stopped to allow for endotracheal intubation

34
Q

TREATMENT OF ECG PATHO

A
  • pacemaker: heart beats too slowly or it pauses, causing fainting spells or other symptoms. Used to prevent or treat heartbeat that is too fast or irregular
  • cardioversion to correct heartbeat too fast (tachycardia) or irregular (fibrillation)
    Indications: atrial fibrillation, atrial flutter, ventricular & supra ventricular tachycardia
35
Q

Heart rate variability: def, type of measurement & changes

A

= physiological phenomenon of variation in time interval between heartbeat

  • Measured by variation in beat-to-beat interval
  • HRV Changes = has been shown to be predictor of mortality in cardiovascular disease patients