Cardiovascular Needs and Angina Flashcards
Cardiovascular Disease Stats
Number 1 cause of death in the US. Leading cause of death in women. 1/5 people living with CAD.
Coronary Arteries
Feed O2 blood to the heart
Two main coronary arteries
LCA and RCA
When does blood flow to the myocardium occur?
Diastole (when heart is at rest)
MAP required to maintain adequate coronary blood flow
> 60, otherwise decreased tissue perfusion and damage and may result in CP (due to lack of blood flow)
9 external landmarks of the heart (arteries)
Aorta, RCA, posterior lateral artery, posterior descending artery, diagonal artery, obtuse marginal artery, left anterior descending artery, left circumflex artery, left main coronary artery
Cardiac conduction system
Specialized tissue capable of rhythmic electrical impulse formation seen on EKG
6 cardiac conduction landmarks
SA node (pacemaker), AV node, Bundle of his, Right and Left bundle branches, Purkinje fiber system
RCA
Encompasses heart and feeds the right side
Left main
feeds left side of the heart
Blood perfusion per beat
60 ml of blood per beat and can double with activity
layers of the heart
epi, myo, and endo
Pathway of blood in the heart
right atrium, right ventricle through the tricuspid, lungs through pulmonic valve to pulmonary artery, back to heart through left atrium, through mitral valve to left ventricle, through aortic valve to aorta
CV risk assessment
Thorough history, med hx, lifestyle hx (smoking, drinking, exercise), diet hx, dental hx (peridontal disease), PE (hip to waist ratio, pain, SOB, edema, fatigue, lipids cholesterol), women: post- menopausal, BMI >30, socioeconomic class (foods, occupation, fam support)
What percentage of deaths occur from cardiovascular disease in the US annually?
42%
Physical assessment
general appearance, skin, BP and peripheral pulses (bounding), heart sounds (APETM), lung sounds (fluid backup), psychosocial assessment (anxiety, depression, denial), EKG
CAD
Narrowing and/ or complete occlusion. Long latent periods (30-40 yrs) fatty streaks in childhood and sx in middle age
Causes of artery narrowing
atherosclerosis, thrombosis, spasm, coronary dissection, aneurysm formation
Fatty streaks (CAD beginning)
result from the buildup of fat in the artery wall
Atheroma (CAD)
As more fat and cellular debris collect, atheromas develop. As atheroma grows, it may begin to encroach on vessel lumen.
Vulnerable Plaques (CAD)
Plaques that contain at least 40% lipid in their core and
have a thin cap are more likely to rupture,
resulting in occlusion of the artery by a blood clot
Plaque rupture (CAD)
Vulnerable plaques that rupture trigger thrombus
formation and potential occlusion
Occlusion (CAD)
Thrombus formation often results in partial or complete occlusion leading to myocardial ischemia, infarction, and/or death
Ischemia
lack of oxygen flow to tissues
Infarction
death of tissue due to lack of oxygen
Major modifiable risk factors for CAD
Elevated serum lipids, HTN, smoking, impaired glucose tolerance, diet (inc sat fat, cholesterol, calories), physical activity
Risk of smoking and CAD
dec HDL and inc LDL and TG, impaired O2 transport, inc myocardial O2 demand, may alter intimal endothelial permeability and foster platelet agglutination
Risk of smoking and CAD
dec HDL and inc LDL and TG, impaired O2 transport, inc myocardial O2 demand, may alter intimal endothelial permeability and foster platelet agglutination
4 subtypes of cholesterol
HDL men >40 and women >50
LDL <100
VLDL (worse form of LDL)
triglycerides (TG) <150
Stages of HTN
normal: < 120/80
preHTN: 120/80 - 139/89
HTN: >135/85
Risk of oral contraceptives and CAD
after age 35: alters blood coag, platelet function, fibrinolytic activity, integrity of vascular endothelium