Cardiovascular Meds

Question 1

Alteplase

Answer 1

Initial - 15mg IV push over 1-2min
Second dose - 0.75mg/kg IV over 30min, max dose 50mg
Third dose - 0.5mg/kg IV over 60min max dose 35mg

Question 2

Reteplase

Answer 2

Initial - 10 units IV push over 2min

Second dose - 10 units IV push over 2min

Question 3

Tenecteplase

Answer 3

30-50mg IV push over 5sec (based on body weight)

Question 4

Nitroglycerin - Sublingual

Answer 4

1 spray or tablet (400mcg) q5min x3

Question 5

Nitroglycerin - Infusion

Answer 5

10mcg/min IV, titrate by 5mcg/min q3-5min to 20mcg/min

Question 6

Nitroglycerin - Max

Answer 6

200mcg/min

Question 7

Aspirin

Answer 7

162-325mg

Question 8

Clopidogrel

Answer 8

300-600mg PO

75mg PO daily

Question 9

Prasugrel

Answer 9

60mg PO

10mg PO daily

Question 10

Ticagrelor

Answer 10

180mg PO

90mg PO BID

Question 11

Eptifibatide

Answer 11

180mcg/kg IV loading dose
2mcg/kg/min infusion (max 15mg/hr)
Renal dosing for CrCl <50 - 1mcg/kg/min

Question 12

Abciximab

Answer 12

0.25mg/kg IV loading dose

10mcg/min IV for 18-24hrs infusion

Question 13

Heparin

Answer 13

60 units/kg IV (max 5000 units) loading dose

12 units/kg/hr (max 1000 units/hr) infusion

Question 14

LMWH - Enoxaparin

Answer 14

1mg/kg sub-q q12hrs

Question 15

Fondaparinux

Answer 15

2. 5mg/kg IV push loading dose

2. 5mg/kg sub-q dialy

Question 16

Esmolol

Answer 16

500mcg/kg IV bolus over 1min loading dose
50mcg/kg/min, titrate 50mcg/kg/min q4min infusion
Max 300mcg/kg/min

Question 17

Diltiazem

Answer 17

0.25mg/kg IV over 2min loading dose (10-20mg IV bolus, 2nd dose 15-25mg IV push)
5mg/hr titrate by 5mg/hr q15min infusion
Max 15mg/hr

Question 18

Nicardipine

Answer 18

5mg/hr titrate by 2.5mg/hr q5min infusion

Max 15mg/hr

Question 19

Labetalol

Answer 19

20mg IV over 2 min loading dose
2mg/min titrate by 0.5mg/min q10min infusion
Max 8mg/min

Question 20

Nitroprusside

Answer 20

0.25-0.5mcg/kg/min titrate by 0.25-0.5mcg/kg/min q2-5min

Max 10mcg/kg/min

Question 21

Fenoldopam

Answer 21

0.03-0.1mcg/kg/min titrate by 0.05-0.1mcg/kg/min

Max 1.6mcg/kg/min

Question 22

Metoprolol

Answer 22

2.5-5mg IV bolus, may repeat every 5min up to 15mg total in 10-15min
25mg PO q15hrs maintenance

Question 23

Digoxin

Answer 23

250mcg q2hrs IV or PO loading dose (cumulative max dose of 1.5mg)
125-375mcg IV/PO daily maintenance

Question 24

Amiodarone

Answer 24

150mg IV bolus loading dose

1mg/min for 6hrs, then 0.5mgmin infusion

Question 25

Furosemide

Answer 25

40mg IV, increase by 20mg IV after 1-2hrs Max 160mg/dose 10-40mg/hr infusion

Question 26

Bumetanide

Answer 26

0.5-1mg IV 10mg/day max 0.5-2mg/hr infusion

Question 27

Torsemide

Answer 27

20mg IV repeat in 2-3hrs 200mg/day max 5-20mg/hr infusion

Question 28

Metolazone

Answer 28

2.5mg PO | Max 20mg/day

Question 29

Chlorothiazide

Answer 29

500mg IV | Max 1000mg/day

Question 30

Captopril

Answer 30

12. 5mg sublingual x1 | 12. 5-50mg PO TID

Question 31

Enalapril (PO) or Enaliprilat (IV)

Answer 31

2. 5mg PO or 1.25mg IV | 2. 5-20mg PO BID

Question 32

Adenosine

Answer 32

1st dose: 6mg IV push 2nd dose: 12mg IV push, may repeat 3mg if in a central line

Question 33

Verapamil

Answer 33

1st dose: 0.075mg/kg IV (5mg) 2nd dose: 0.15mg/kg IV (5-10mg) Max 30mg IV

Question 34

Flecainide

Answer 34

2mg/kg over 10min

Question 35

Propafenone

Answer 35

2mg/kg over 10min

Question 36

Procainamide

Answer 36

100mg IV over 2min q5min, 20-50mg/min for 20-35min loading dose Max 17mg/kg or 1000mg loading 1-4mg/min infusion Max 1g load or 9g/day

Question 37

Ibutilide

Answer 37

1mg over 10min

Question 38

Lidocaine

Answer 38

1-1.5mg/kg IV, can repeat at 0.5-0.75mg/kg q5min Max 3mg/kg loading 1-4mg/min infusion