Cardiovascular drugs - categories only Flashcards

1
Q

Heparin

A

anticoagulant

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2
Q

LMWH

A

anticoagulant

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3
Q

Warfarin

A

anticoagulant (oral)

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4
Q

Protamine sulfate

A

anti-heparin

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5
Q

fondaparinux

A

Anti-10a

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6
Q

Hirudin

A

HIT-avoidance anti-coagulant

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7
Q

Bivalirudin

A

HIT-avoidance anti-coagulant

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8
Q

Argatroban

A

2a inhibitor

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9
Q

AT3 concentrate

A

anticoagulant

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10
Q

Vitamin K

A

Warfarin antidote

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11
Q

Recombinant 7a

A

Warfarin antidote

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12
Q

Fresh frozen plasma

A

Warfarin antidote

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13
Q

Tirofiban

A

GPIIa/IIIb inhibitor

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14
Q

Abciximab

A

GPIIa/IIIb inhibitor

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15
Q

Eptifibamibe

A

GPIIa/IIIb inhibitor

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16
Q

Zileuton

A

Leukotriene inhibitor

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17
Q

Monteleukast

A

Leukotriene inhibitor

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18
Q

Zarirkulast

A

Leukotriene inhibitor

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19
Q

Clopidogrel

A

ADP receptor inhibitor

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20
Q

Prasugrel

A

ADP receptor inhibitor

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21
Q

Ticlopidine

A

ADP receptor inhibitor

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22
Q

Ticagrelor

A

ADP receptor inhibitor

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23
Q

Cangrelor

A

ADP receptor inhibitor

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24
Q

Cilostazol

A

PDE3 blocker - antiplatelet

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25
Q

Dipyramidol

A

PDE3 blocker - antiplatelet

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26
Q

Tenecteplase

A

recombinant t-PA (MI, stroke)

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27
Q

Reteplase

A

recombinant t-PA (MI, stroke)

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28
Q

Alteplase

A

recombinant t-PA (MI, stroke)

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29
Q

Streptokinase

A

recombinant t-PA (PE, MI, stroke)

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30
Q

Urokinase

A

recombinant t-PA (PE, MI, stroke)

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31
Q

Ancrod

A

recombinant t-PA (stroke)

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32
Q

Pravustatin

A

anti-LDL (non CYP)

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33
Q

Rosuvastatin

A

anti-LDL

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34
Q

Lovastatin

A

anti-LDL

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35
Q

Fluvastatin

A

anti-LDL

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36
Q

Simvistatin

A

anti-LDL

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37
Q

Cholestyramine

A

anti-LDL (bile acid resin), increases TAG though!

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38
Q

Colestipol

A

anti-LDL (bile acid resin), increases TAG though!

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39
Q

Colesevalam

A

anti-LDL (bile acid resin), increases TAG though!

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40
Q

Ezetimebe

A

Cholesterol absorption inhibitor

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41
Q

Evolocumab

A

anti-LDL (PCSK9 inhibitor)

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42
Q

Alirocumab

A

anti-LDL (PCSK9 inhibitor)

Heterozygous for LDLR

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43
Q

Lomitapide

A

anti-LDL (MTP inhibitor)

Homozygous null LDLR

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44
Q

Mipomerson

A

anti-LDL (APO-B inhibitor)

Homozygous null LDLR

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45
Q

Niacin

A

HDL booster

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46
Q

Gemfibrozil

A

TAG reducer

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47
Q

Fenofibrate

A

TAG reducer

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48
Q

NO

A

vasodilator

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49
Q

Nitroprusside

A

A/V dilator

50
Q

Hydralazine

A

vasodilator

51
Q

Nitroglycerin

A

vasodilator

52
Q

Isosorbide dinitrate

A

vasodilator

53
Q

Captopril

A

ACE inhibitor

54
Q

Lisinopril

A

ACE inhibitor

55
Q

Enalapril

A

ACE inhibitor

56
Q

Ramipril

A

ACE inhibitor

57
Q

Losartan

A

Angiotensin II receptor blocker (ARB)

58
Q

Icatibant

A

Bradykinin receptor blocker

59
Q

Aprotinin

A

Kallikrein blocker

60
Q

Desmopressin

A

releases endothelial VWF/VIII

61
Q

Bosentan

A

Endothelin antagonist

62
Q

Acetazolamide

A

CA inhibitor diuretic

63
Q

Dorzolamide

A

CA inhibitor diuretic

64
Q

Methazolamide

A

CA inhibitor diuretic

65
Q

Dichlorophenamide

A

CA inhibitor diuretic

66
Q

Mannitol

A

Osmotic diuretic

67
Q

Furosamide

A

Loop diuretic

68
Q

Bumetanide

A

Loop diuretic

69
Q

Torsemide

A

Loop diuretic

70
Q

Ethacrynic acide

A

Loop diuretic (for sulfa allergy)

71
Q

HCTZ

A

Thiazide diuretic

72
Q

Chlorothiazide

A

Thiazide diuretic

73
Q

Chlorothalidone

A

Thiazide diuretic

74
Q

Indapamide

A

Thiazide diuretic

75
Q

Metolazone

A

Thiazide diuretic - for renal failure, non sulfa structure

76
Q

Spironolactone

A

K+ sparing diuretic (aldosterone R blocker)

77
Q

Eplerenone

A

K+ sparing diuretic (aldosterone R blocker)

78
Q

Amiloride

A

K+ sparing diuretic

ENaC block

79
Q

Triamterene

A

K+ sparing diuretic

ENaC block

80
Q

Tolvaptan

A

AVP receptor blocker

81
Q

Conivaptan

A

AVP receptor blocker

82
Q

Aminocaproic acid

A

anti-fibrinolytic (pro-clot)

83
Q

Transexemic acid

A

anti-fibrinolytic (pro-clot)

84
Q

Aprotinin (trasylol)

A

anti-fibrinolytic (pro-clot)

85
Q

Alpha-2-antiplasmin

A

anti-fibrinolytic (pro-clot)

86
Q

PAI-1

A

anti-fibrinolytic (pro-clot)

87
Q

13a

A

anti-fibrinolytic (pro-clot)

88
Q

Procainamide

A

Anti-arrhythmic (1A)

89
Q

Quinidine

A

Anti-arrhythmic (1A) - cinchonism

90
Q

Disopyramide

A

Anti-arrhythmic (1A)

91
Q

Lidocaine

A

Anti-arrhythmic (1B)

92
Q

Mexilitene

A

Anti-arrhythmic (1B)

93
Q

Flecainide

A

Anti-arrhythmic (1C)

94
Q

Propafenone

A

Anti-arrhythmic (1C)

95
Q

Propanalol

A

nonspecific B-blocker

Antiarrhythmic

96
Q

Esmolol

A

B-blocker (short half-life) - antiarrhythmic

97
Q

Amiodarone

A

AP prolonger

Anti-arrhythmic (Class III)

98
Q

Dronedarone

A

AP prolonger

Anti-arrhythmic (Class III)

99
Q

Sotalol

A

AP prolonger (Class III)

100
Q

Verapimil

A

CCB: neg ino/chronotrope

101
Q

Diltiazem

A

CCB: neg ino/chronotrope

102
Q

Adenosine

A

Anti-arrhythmic (temporary flatline…restarts heart)

103
Q

Nifedipine

A

CCB

104
Q

Losartan

A

ARB

105
Q

Reserpine

A

sympatholytic

106
Q

Methyldopa

A

sympatholytic

107
Q

Guanfacine

A

sympatholytic

108
Q

Clonidine

A

sympatholytic

109
Q

Phenoxybenzamine

A

non-selective alpha blocker

110
Q

Prazosin

A

a1 blocker

111
Q

Minoxidil

A

vasodilator

112
Q

Amlodipine

A

CCB

113
Q

Nicarpidine

A

CCB

114
Q

Rinolazine

A

P-Fox blocker to reduce O2 consumption for angina

115
Q

Ivabradine

A

I-funny channel blocker (anti-anginal)

116
Q

Niseritide

A

venodilator

117
Q

Nitroglycerin

A

venodilator

118
Q

Dobutamine

A

B1 agonist –> boost CO

119
Q

Milrinone

A

PDE-i for acute CHF

120
Q

Amrinone

A

PDEI-i for acute CHF

121
Q

Digitalis

A

positive inotrope

122
Q

LCZ696

A

anti-remodelling