Cardiovascular Drugs

Question 1

What type of drug is Digoxin? What do these drugs do and what are they often used to treat?

Answer 1

. Cardiac glycoside
. Inhibits sodium-potassium ATPase to decrease heart rate
. Often used for AF, used to be used for HF but not anymore

Question 2

What do diuretics do?

Answer 2

Increase water loss in order to decrease blood volume and thus decrease blood pressure

Question 3

What type of drug is Ramipril? How does it work and what is it used for?

Answer 3

. ACE inhibitor

. Inhibits ACE to reduce production of angiotensin II to lower BP

Question 4

What type of drug is amlodipine? How does it work and what is it used for?

Answer 4

. Calcium channel antagonist
. Block calcium channels so fewer APs to heart muscle
. Slows heart rate and causes blood vessels to dilate = lowers BP

Question 5

What kind of drug is simvastatin? How does it work?

Answer 5

Statin, blocks enzyme that liver uses to produce cholesterol

Question 6

What kind of drug is streptokinase? How does it work?

Answer 6

. Fibrinolytic anticoagulant

. Activates plasminogen to form plasmin, which degrades fibrin so it can’t combine with platelets to form a clot

Question 7

What kind of drug is aspirin? How does it work?

Answer 7

. Antiplatelet

. Low dose aspirin inhibits cyclo-oxygenase (COX) so that platelets aren’t formed

Question 8

What kind of drug is enoxaparin? How does it work?

Answer 8

Injectable anticoagulant (it’s a heparin), activates antithrombin III to bust clots

Question 9

What type of drug is Warfarin?

Answer 9

Oral anticoagulant