CARDIOVASCULAR DRUGS

Question 1

Drug class of hypertensive medication that lower BP by decreasing volume and a direct vascular
effect that is not yet fully understood

Answer 1

DIURETICS

Question 2

MOA: Inhibit Na+/Cl- transporter in DCT
Other: cause moderate diuresis and reabsorption of
calcium

Answer 2

THIAZIDE: Hydrochlorothiaziade

Question 3

SE of thiazide diuretic?

Answer 3

Hypokalemic metabolic alkalosis

and

HYPER-GLUC: HyperGlycemia,
HyperLipidemia, HyperUricemia,
HyperCalcemia

Question 4

MOA: what anti htn?

Inhibit Na/K/2Cl transporter in thick ascending limb of
loop of Henle. (See the difference between thiazide)
Others: Powerful diuresis, increased calcium excretion

Answer 4

Loop Diuretics: Furosemide

Question 5

SE of Loop Diuretics: Furosemide?

Answer 5

“OH DANG”
O-totoxicity, H-ypokalemia, D-ehydration, A-llergy to sulfa,
N-ephritis, G-out

Question 6

SE of Clonidine?

Answer 6

Rebound hypertension

Question 7

SE of Methyldopa?

Answer 7

Hemolytic anemia

Question 8

Most commonly used maintenance meds for hypertension in
pregnancy

Answer 8

Methyldopa

Question 9

SE of alpha blockers Prazosin, Tamsulosin (-zosin)

Answer 9

First dose syncope/orthostatic hypotension

Question 10

DO NOT GIVE in acute heart failure. But this is used
in chronic HF to decrease demand

Answer 10

Beta Blockers

Question 11

What drugs are used to control blood pressure in pheochromocytoma? (3)

Answer 11

Phenoxybenzamine, Phentolamine or Labetalol

Question 12

MOA of hydralazine?

Answer 12

Alters intracellular Ca2+ metabolism.
Vasodilates ARTERIOLES = decreased AFTERLOAD

Question 13

Non dihydropyridine CCB?

Answer 13

Verapamil and Diltiazem

NVD

Question 14

Dihydropyridine CCBs?

Answer 14

-dipines

Question 15

MOST EFFECTIVE VASODILATOR

Answer 15

Nitroprusside