Cardiovascular Drugs Flashcards
What are the two primary functions of the Circulatory system?
(1) delivery of oxygen, nutrients, hormones, electrolytes, and other essentials to cells and
(2) removal of carbon dioxide and metabolic wastes from cells. In addition, the system helps fight infection.
What composed the circulatory system?
Heart and Blood vessels
What are the determinants of Cardiac Output?
- Heart Rate
- Stroke Volume
- Preload
- Afterload
What do we call if the persistent systolic pressure is greater than 140mmHg and/or diastolic pressure is greater than 90mmHg?
Hypertension
What is determined by the product of the cardiac output and systemic vascular resistance?
Blood pressure
What are the drugs that accelerate the rate of urine formation that results to the removal of sodium and water from the body?
Diuretics
Where do the carbonic anhydrase inhibitors diuretics work?
Proximal convoluted tubule
Where do loop diuretics acts?
Ascending Loop of Henle
What are the examples of loop diuretics drugs?
Bumetanide, Furosemide, Torsemide
Where do osmotic diuretics works?
Entire nephron especially in the Loop of Henle (LoH) and Proximal convoluted tubule (PCT)
What is the drug of choice for preventing kidney damage during acute kidney injury and reduction of intracranial pressure and cerebral edema?
Osmotic
Where do potassium-sparing works?
Collecting ducts and Distal convoluted tubule (DCT)
Where do Thiazides work?
Distal convoluted tubule (DCT)
What adrenergic antagonists act on the brain by decreasing Norepinephrine production
Central Acting Adrenergic Antagonists
What adrenergic antagonists act on the heart and blood vessels?
Peripheral Acting Adrenergic Antagonist
