Cardiovascular Drugs Flashcards
Is determined by 1) myocardial contractility (force with which the ventricles contract), 2) cardiac afterload, 3) cardiac preload
Stroke Volume
Is the amount of tension (stretch) applied to a muscle before contraction = force of venous return
Preload
Is the load against which a muscle exerts its force = arterial pressure that the left ventricle overcomes to eject blood
Afterload
Defined as a persistent systolic pressure of greater than 140mmHg and/or a diastolic pressure of greater than 90mmHg
Hypertension
Is the amount of blood ejected from the left ventricle and measured in Lpm
Cardiac Output
Is the resistance to blood flow that is determined by the diameter of the blood vessels and vascular musculature
SVR (Systematic Vascular Resistance)
Drugs that accelerate the rate of urine formation that results to the removal of sodium and water from the body
Diuretics
Acts on the brain by decreasing NE production
Central Acting
Acts at the heart and blood vessels
Peripheral Acting
Blocks binding of Angiotension II to its receptors and primarily affects the vascular smooth muscle and adrenal gland
ARBs