Cardiovascular Drugs Flashcards
Controlled by the ANS?
Heart rate
Determined by 1) myocadial contractility, forced with which the ventricles contract 2) cardic afterload. 3) cardiac preload.
Stroke volume
Amount of tension (strech) applied to muscle before contraction- force of venous rectum?
Preload
Load against which a muscle exerts its force- arterial pressure that the left ventricle overcomes to eject blood?
Afterload
Defined as persistent systolic pressure of greater than 140mmHg and/or a diastolic pressure of greater than 90mmHg.
Hypertension
Determined by the product cardiac output and systemic vascular resistance?
Blood pressure
Resistance to blood flaw that is determined by the diameter of the blood vessels and vascular musculature?
SVR
What is the goal goal of antihypertensive therapy?
Reduction of cardiovascular and renal morbidity morality
What drugs that accelerate the rate of urine formation results to the removal sodium and water from the body.
Dieretics
Energy source stores in adipose tissue?
T6
Used to make steriod hormones, cell membranes, bile acids?
Cholesterol
Combination of T6 and chol which transport lipids via the blood?
Lipoprotein
Precuresor lesion of atherosclerosis from foam cell?
Fatty streak
It is also a vitamin, B3 with a MOA unkwon, but believed to inhabit lipolysis in adipose tissue, increase activity of lipoprotein lipae. It’s indication is to lovwer lipid levels and increase HDL?
Niacin (nicotin acid)
It’s indication is to decrease T6 and increase HDL levels, T3,T4 and T5 hyperlipidemia?
Fibric acid derivatives.
