Cardiovascular and Resp Flashcards
CVS causes of clubbing?
IE, cyanotic congenital heart disease
Types of pansystolic murmurs
MR, TR, VSD, aortopulmonary shunt
What type of murmurs are common in children and high output states?
Ejection systolic
Name two high output states
Pregnancy, tachy
What heart sound is caused by calcified aortic valve or aortic regurg
Softer second heart sound
In systemic hypertension what happens to S2?
Louder
Causes of postural hypotension (HANDI)
hypovolaemia (dehydration), hypopituitarism, addisons, neuropathy (autonomic eg diabetes), drugs, idiopathic
Drugs that cause postural hypotension
anti-hypertensives, anti-psychotics, tricyclics, diuretics, vasodilators
How does jaundice occur as CVS sign?
Severe CCF backing in to liver–>congestion
A rare cause is prosthetic valves causing RBC haemolysis
Radiofemoral delay=
Coarctation of aorta (narrowing of aorta at ductus arteriosus joins descending aorta)
Radio-radio delay causes
Subclavian narrowing by atherosclerosis, aneurysm, subclavian steel, dissection
Bounding pulse is characteristic of what?
Aortic regurgitation
Pulsus alternans is characteristic of what?
LV failure
Clubbing is defined as…
loss of hyponichial angle (depth of DPD>IPD)
Causes of pulsus paradoxus
Pericarditis, pericardial effusion, asthma
Mitral facies are caused by…
pulmonary hypertension + low cardiac output usually from mitral stenosis (rare now)
Slow rising pulse =
aortic stenosis
Describe kussumals sign
Rise of JVP on inspiration (usually a fall due to increased RV filling) due to restricted RV filling that can be caused by cardiac tamponade, constrictive pericarditis or RV infarction)
How high can JVP be above sternal angle?
3cm
5 things to Distinguish JVP from carotid…
- change with breathing/posture
- adominojugular reflex
- fills from above
- double wave form
- not palpable
common cause of canon a wave
complete heart block (atria contacts against closed tricuspid- everything out of whack)
Signs of LV failure
exertional dyspnoea, orthopnoea, PND, central and peripheral cyanosis
Tachycardia, low pulse pressure, pulsus alternans
Displaced apex beat
S3, mitral regurg
Basal inspiratory crackles
Central cyanosis=
pulmonary oedema
Peripheral cyanosis=
low cardiac output
Cheyne stoke breathing is…
periods of hyperventilation progressing followed by period of apnoea (this is cyclical). caused by loss of control of respiratory system negative feedback
Causes of LV failure
Ischaemic Heart Disease, Cardiomyopathy, Valvular disease (MR/AR), Hypertension
Precipitating causes of LV failure
Anaemia, Thyrotoxicosis, AF
3 ejection systolic murmurs
AS, PS, HOCM
How does HOCM cause double impulse in ejection systolic murmur?
anterior movement of mitral valve in early systole causes blockage and results in double pulsation
What is HOCM and why dangerous?
Congenital defect in sarcomeres causing hypertrophy and myocardial disarray. Can cause sudden cardiac death
HOCM symptoms
similar to CCF, but treatment vastly different (diuretics make it worse!)
How HOCM differs from concentric hypertrophy from hypertension
HOCM is usually assymetric (just septal)
Causes of cardiomyopathy?
IHD, valvular, alcohol, idiopathic, drugs, pregnancy, BP, thyroid, haemochromatosis, viral, diabetes
Describe murmur of MVP?
Late systolic + midsystolic click
Early diastolic murmurs
Aortic/pulmonary regurg
Mid-diastolic murmurs
mitral stenosis
Why do fundoscopy for CVS exam?
Hypertension/diabetes, roth spots in IE
Other examination for CVS exam
temp, urine, lying/standing BP
Ankylosing spondylitis is linked with which murmur?
Aortic regurg
What type of murmurs are louder on inspiration?
right sided
What murmur is louder with valsava? all else decreased
HOCM
What murmur is louder with handgrip?
MR
Which murmurs get louder with forward lean?
Aortic regurgitation, pericardial rub
What is a 4th heart sound?
atrial contraction against stiff ventricle
Symptoms of RV failure
ankle, sacral oedema, abdo distension peripheral cyanosis large v wave right ventricular heave pansystolic mrumur-->tricuspid regurg pulsatile liver
Causes of RV failure?
pulm HTN, LV fail, MI, cardiomyopathy, valvular
Symptoms of Aortic stenosis
exertional chest pain, exertional dyspnoea, exertional syncope, small volume pulse
Murmur of aortic stenosis
Ejection systolic, loudest over aortic area with radiation to carotids. Often associated aortic regurgitation
What is austin flint murmur?
strong aortic regurg causing mitral regurg
things to look for on general inspection
cyanosis, dyspnoea (obvious distress), scars, deformities
murmurs to suspect with severe sudden onset chest pain
MR (papillary muscle rupture), VSD from an MI
Indications for defibrillator implantation
Heart failure patients with LVEF <30, NYHA I. Post VF
Brugada, long QT, sustained VT, HOCM
Describe NYHA heart failure criteria
I. No symptoms
II. Mild symptoms with ordinary activity
III. 100m makes breathless
IV. At rest
Pacemaker indications
Arrythmias (AV block, long QT), Post MI, Vasovagal syncope, HOCM
What is cardiac resynchronisation therapy?
Resynchronisation of dyssonchronous ventricular action in patients with heart failure. Can be done with or without ICD
Signs on CXR of COPD/cor pulmonale
Overinflated lungs, prominent pulmonary arteries, flat diaphragms
Globular heart on CXR=
pericardial effusion
Hallmark of bronchiecstasis/CF on CXR
thickened bronchial walls
Important extra components in resp history?
job, travel, pets
DDx pleuritic chest pain
rib fracture, pneumonia, PE, pneumothorax, pericarditis
Hypertrophic osteoarthropathy is associated with which respiratory condition?
Carcinoma of lung
Volume loaded apex beat murmur
MR
Pressure loaded apex beat murmur
AS
Distinguish between AS and MR
Ejection vs Pan, Radiation, Pressure vs Volume loaded
What is the valsava manouvre used to assess?
Left heart failure- changes in blood pressure
which murmurs increase on inspiration?
right sided
which murmurs increase on lean forward and expiration?
aortic regurg
which murmurs increase on hand grip?
mitral regurg
describe a murmur…
grade, type, duration, loudest where, radiation
grading for murmurs…
grade II- soft, no thrill, III- moderate, IV- loud + just palpable thrill, V- loud and easily palpable thrill, VI- no steth
valsava increases which murmurs?
HOCM
causes of aortic stenosis?
degenerative calcification, rheumatic fever, congenital bicuspid valve, hypertension (DM risk factor)
causes of aortic regurg?
rheumatic, congenital bicuspid, ankylosing spondylitis, marfans
Symptoms of MR?
Dyspnoea, fatigue
Common pulse of MR
AF
On auscultation for MR
S1 soft, S3, pansystolic at apex–>axillae
Causes of MR
MVP, degenerative change, rheumatic, papillary muscle dysfunction, cardiomyopathy, marfans, RA, ankylosing spond
Signs of tricuspid regurg
Large v wave, RV heave, increase inspiration, pulsatile abdomen, oedema
Causes of tricuspid regurg
RF, IE, prolapse, papillary muscle
Common signs right heart fail
oedema, pulsatile liver, raised JVP, peripheral cyanosis
Common signs left hear fail
orthop, PND, exertional dyspnoea, fatigue, central cyanosis, basal creps, displaced apex beat, S3 on auscultation
Autoimmune cases clubbing
SLE, RA, antophospholipid, TRAUMA
Oslers nodes are…
painful red raised nodules on hands
janeway lesions are
flat painless lesions
Causes of atrial fib
MI, valvular disease, hypertension, thyrotoxicosis
JVP normally how high above sternal angle
5cm
Kussumauls sign caused when…
RV filling limited eg constrictive peri, tamponade, RV infarct
Causes high JVP
RV fail, tricuspid stenosis/regurg, constrictive peri, SVC obstruction, fluid overload
Causes loud S1
mitral stenosis
causes soft S1
heart block, LBBB, MR
Causes loud S2
pulm hypertension, AS, hypertension
Causes soft S2
aortic regurg, aortic valve calcification
Dull percusion note Ddx
Consolidation, collapse, effusion, fibrosis, pleural thickening
Hyper-resonant percussion note DDx
pneumothorax, COPD
Bronchial breathing DDx
Consolidation, above pleural effusion, next to pericardial effusion, localized fibrosis
Silent chest=
life threatening asthma
Wheeze is caused by… and has DDx
air expired through narrow airway
COPD, asthma, tumour, pulmonary oedema (LVF)
Stridor is an… caused by…
high pitched inspiratory wheeze
tracheal obstruction
Crackles are caused by…
opening of blocked airway
Early crackles are caused by…
COPD (small airways)
Late or pan-inspiratory crackles are caused by
Pulmonary fibrosis (fine crackles), alveolar oedema (medium crackles), bronchiecstasis (coarse crackles)
Vocal resonance is increased in.. decreased …
consolidation, effusion
Wheezes are… crackles are…
continuous, interrupted
Pleural rub causes
adjacent pneumonia, pulmonary infarct
Extra examinations to do in resp…
O2 sats, temp, Peak flow, forced expiratory time, spirometry, CXR
Yellow/green sputum=
infected- pneumonia/bronchiecstasis
Pink+smelly sputum=
pulmonary oedema
DDx haemoptysis
malignancy, TB, infarct, PE, trauma
Bronchiecstasis is…
dilation of bronchi resulting in impaired clearance of mucous and chronic infection
Signs of bronchiecstasis
Fever, clubbing, large amount purulent sputum
Coarse pan inspiratory crackles
Can cause cor-pulmonale
Causes bronchiectasis
cystic fibrosis, primary cilliary dyskinesia
childhood infection, TB, bronchial adenoma
Emphysema signs
barrel chest, pursed lip breathing, use of accesory muscles, reduced chest expansion, hyperresonant percussion, decreased breath sounds, early inspiratory crackles
Causes emphysema
smoking, alpha-1 anti-trypsin
Indication for pneumonectomy
Cancer, TB
Signs of pneumonectomy
Dyspnoea, tracheal/mediastinal deviation away from side of surgery, decreased expansion, hyperresonant percussion, breath sounds harsher over side of pneumonectomy
Pneumoectomy vs lobectomy signs
trachea still central in lobectomy
Flapping hands sign of…
CO2 retention–>COPD
Pulmonary fibrosis results in…
impaired gas exchange and causes VQ mismatch
Causes of fibrosis in upper lobe
SCHART (silicosis, sarcoid, coal worker, histiocytosis, ankylosing spondylitis, radiation, TB)
Causes of fibrosis lower lobe
RASCO (RA, asbestosis, scleroderma, cryptogenic firbosing alveolitis, other (eg drugs)
Signs of fibrosis
dyspnoea, clubbing, cyanosis, reduced expansion, dull percussion, fine late inspiratory crackles
signs of associated CT disease eg RA, SLE, scleroderma
Horner’s syndrome cause and symptoms
apical lung tumour
constricted pupils, partial ptosis, loss of sweating
CURB-65=
confusion, urea, respiratory rate, BP
Mx Bronchiectasis
Postural drainage, Abx, bronchodilators, corticosteroids
COPD vs Restrictive on spirometry
FEV1/FVC decreased in obstructive but not restrictive
Tracheal deviation toward lesion DDx
Collapse, fibrosis
Tracheal deviation away DDx
Consolidation, penumothorax, effusion
Exudative pleural effusion DDx
pneumo, neoplasm, TB, RA, SLE, drugs
Transudative effusion DDx
CCF, hypoalbulanaemia, hypothyroid