Cardiovascular Flashcards
ACE inhibitors
Captopril , Enalapril
Angiotensin Receptor Blocker
Sartans
Beta adrenoceptor antagonist
Propranolol ( non selective antagonist ) , metapolol ( B1 selective antagonist )
Calcium channel blocker
Verapamil , Diltiazem , Nifendipine , Amlodipine
Loop Diuretics
Furosemide
Thiazide
Hydrochlorothiazide
K+ sparing diuretics ( sodium channel blocker )
amiloride ,
K+ sparing diuretics( aldosterone antagonist )</p>
spironolactone , eplerenome
Endothelin blockers
Bosentan
Grade 1 Mild Hypertension
> SBP 140 / >DBP 90
Grade 2 Moderate hypertension
> SBP 160/>DBP 100
Grade 3 Severe hypertension
> =SBP 180 / >DBP=110
digoxin
inhibition of Na/K Atpase pump and increase myocardial intracelluar calcium
dobutamine
Beta 1 agonist
rt -PA
clot busters
Heparin
I.V adminsitration , act with antithrombin III , inhibit clotting steps, over dose treat with protamine
Warfarin
oral administration , Vit K antagonist
Asprin
COX inhibitors
Clopidogrel
ADP Receptor blocker
Dipyridamole
increase adenosine /cAMP levels
Mannitol
osmotic diuretics , weak renal vasodilator
Low moleculr weight heparins
Dalteparin , Enoxaparin , increase inactivation by ATIII of factor Xa
abciximab
monoclonal antibody , antagonist of glycoprotein IIb/IIa receptor
statins
HMG Coa Inhibitors
Fibrates
gemfibrozil , fenofibrate , agonist at PPAR alpha ,
Cholesterol absroption inhibitors
bile acid bindind resins
Bile acid binding resins
Colestipol , Cholestyramin
Cholesterol absroption inhibitor
Ezetimibe, inhibit cholesterol absoprtion across intestinal wall
Nicotinic acid
inhibit FA release from adipose tissue
Fish oil
decrease triglycerides
Cholesteryl ester transfer protein
inhibit CETP and rasie HDL cholesterol
Chronotropic
effect that changes the heart rate
Ionotropic
special kind of effect of ahormoneon its targe
Inotrope
agent that alters the force or energy of muscular contractions