Cardiovascular Flashcards
General cause of dilated cardiomyopathy
malfunction of myocardium
Most common causes of dilated cardiomyopathy (4)
Alcohol abuse (most common)
Idiopathic
Myocarditis
Drugs (doxorubicin)
Sequelae of dilated cardiomyopathy
right and left systolic dysfunction, congestive heart failure
Most common first symptom of dilated cardiomyopathy
exertional intolerance
In addition to exertional intolerance, other s/sx dilated cardiomyopathy (4)
dyspnea
orthopnea
lower extremity edema
chest pain
Physical exam in dilated cardiomyopathy (5)
S3 heart sound
JVD
crackles on lungs
mitral regurgitation
lower extremity edema
EKG in dilated cardiomyopathy (3)
nonspecific ST and T wave changes, LBBB
CXR in dilated cardiomyopathy (2)
cardiomegaly, pulmonary vascular congestion
Echo in dilated cardiomyopathy (4)
dilated chambers
thin left ventricular wall
poor wall movement
decreased ejection fraction (often less than 30%)
Non-druggy treatment of dilated cardiomyopathy (3)
withdraw offending agents like booze
sodium restriction
maybe heart transplant
druggy treatment of dilated cardiomyopathy (4)
Diuretics
maybe digoxin
ACE inhibitors (unless contraindicated)
Beta-blockers in stable heart failure
Most common cause of death in young athletes
Ventricular tachyarrhythmias due to hypertrophic cardiomyopathy
Most common cause of hypertrophic cardiomyopathy
Autosomal dominant genetic cause
Pathogenesis of hypertrophic cardiomyopathy
Hypertrophy of cardiac septum leads to LV outflow obstruction, impaired diastolic filling, this leads to pulmonary congestion.
Most patients with hypertrophic cardiomyopathy have these symptoms:
None. Ha. Got you good.
Most common presenting symptoms in hypertrophic cardiomyopathy (3)
Dyspnea on exertion (most common)
angina
syncope
Physical exam, hypertrophic cardiomyopathy (3)
Mitral regurgitation (increases with valsalva, decreases with handgrip and leg elevation)
S4 sound
Prominent left ventricular impulse
Primary diagnostic test for hypertrophic cardiomyopathy (results)
Echocardiogram (septal wall thickness, ejection fraction usually greater than 60%)
EKG in hypertrophic cardiomyopathy
LVH
Treatment of symptomatic hypertrophic cardiomyopathy (3)
Beta-blockers (propanolol)
Calcium channel blockers (verapamil)
Diuretics for fluid overload
Common causes of restrictive cardiomyopathy (5)
Amyloidosis
Sarcoidosis
Hemochromatosis
Post-radiation
Post open-heart surgery
Restrictive cardiomyopathy pathogenesis
Myocardial changes lead to diastolic noncompliance with elevated filling pressures, this leads to pulmonary congestion
Most common symptoms in restrictive cardiomyopathy (2)
Exertional intolerance
fluid retention
Restrictive cardiomyopathy physical exam
elevated JVD
pronounced S4 sound
mitral regurgitation
tricuspid regurgitation
Echocardiogram in restrictive cardiomyopathy (3)
ejection fraction between 25% and 50%
Normal LV thickness
Increased atrial size
EKG in restrictive cardiomyopathy (3)
Low voltage QRS
Nonspecific ST and T wave changes
Definitive / specific diagnostic test for restrictive cardiomyopathy
tissue biopsy
Treatment for restrictive cardiomyopathy (2)
Treat underlying cause
Diuretics
Name this rhythm
Atrial fibrillation
Most common sustained arrhythmia in adults
Atrial fibrillation
Major risk with atrial fibrillation
Risk of intra atrial clot formation
QRS rhythm in atrial fibrillation
irregularly irregular
3 major goals in a-fib treatment
Rate control
Anticoagulation
Rhythm control
Rate control agents in a-fib (3)
Beta blockers (metoprolol)
Calcium channel blockers (verapamil, diltiazem)
digoxin
Anticoagulation agents in a-fib (2)
heparin acutely
warfarin long term
Rhythm control agents in a-fib (2)
Amiodarone is most effective, but side effects are common
Cardioversion may be attempted if no sign of atrial clots
Name this rhythm
atrial flutter
Atrial flutter symptoms (4)
Dizziness
Palpitations
Chest pain
Dyspnea
Best leads to recognize pattern in a-flutter
sawtooth pattern in II, III, aVF
Common ventricular rate in atrial flutter
75-150
Common atrial rate in atrial flutter
250 to 400
Primary treatment of atrial flutter
cardioversion
Acute medication treatments of atrial flutter (2)
Beta blockers (metoprolol, esmolol)
Calcium channel blockers (verapamil, diltiazem)
Long-term medication treatments for atrial flutter (4)
Amiodarone, sotalol, quinidine or procainamide
Definitive treatment of atrial flutter if reentrant site is known
catheter ablation
What the heck is going on here? (ignore those lame arrows)
multifocal atrial tachycardia
Common patients that get multifocal atrial tachycardia (2)
COPD
severe systemic illness
EKG findings in multifocal atrial tachycardia
polymorphic p waves
differing PR intervals
Treatment of multifocal atrial tachycardia (one druggy, one non-druggy)
Treat underlying cause
Calcium channel blockers
What the fuck, yo?
1st degree AV block
Some people with AV block do this for fun
pass out (ok, maybe not so fun)
Definition of first degree AV block
PR greater than 200 milliseconds
Name that rhythm
Second degree, type 1, Wenckebach
Definition of Wenckebach rhythm
progressive increase in PR interval until a P wave is blocked, then the cycle is repeated
What it is?
Second degree AV block, type 2
Definition of second degree AV block type 2
sudden block of a P wave with no change in PR interval
Whaddaya call this?
3rd degree AV block
Third degree AV block definition
Atria and ventricles are controlled by different pacemakers, they fire independently
Look at this table
because I say so
Three non-druggy considerations for treatment of AV block
Asymptomatic patients do not require treatment
Correct any reversible causes
Permanent pacing may be needed
Druggy treatment for symptomatic AV blocks (2)
Atropene or isoproterenol
What’s this all about?
Right bundle branch block
How bout this one?
Left bundle branch block
List some causes for bundle branch blocks (5ish)
Acute MI
Cardiomyopathy
Big PE
Aortic stenosis
being a dork
If a bundle branch block gets conduction across an accessory pathway, it’s called ___________ and it can put the patient at risk of __________
Wolff-Parkinson-White Syndrome
Other cardiac arrhythmias
What EKG finding will suggest WPW?
Delta waves
What duration defines a wide QRS
Greater than 120 milliseconds
A wide QRS without other signs of BBB is called
Intraventricular conduction delay
These 2 medications are contraindicated in WPW
Digoxin and CCB’s
Possible presenting symptoms of paroxysmal supraventricular tachycardia
palpitations or anxiety
another name for paroxysmal supraventricular tachycardia
AV nodal reentry tachycardia
PSVT EKG findings
Rate between 150 and 250
Regular rhythm
Typically no atrial activity seen
PSVT treatment (3-6)
Vagal maneuver
Antianxiety meds
Drug of choice is adenosine
Other rate slowing meds like CCB, beta-blockers, digoxin, may be helpful
Normal rhythm, then interrupted by a narrow QRS, out-of-rhythm beat
Premature atrial contraction
Normal rhythm interrupted by wide-complex QRS
premature ventricular contraction
PVC treatment
Treat underlying caue
may use antiarrhythmics
use of beta-blockers is common
Class Ia antiarrhytmics (3)
Sodium channel blockers like
Quinidine
Procainamide
disopyramide
Class Ib antiarrhythmics (2)
Sodium channel blockers like
Lidocaine
mexiletine
Class Ic antiarrhythmics (2)
Sodium channel blockers like
Flecainide
propafenone
Class II antiarrhythmics (2)
Beta blockers like
Propanolol
Metoprolol
Class III antiarrhythmics (2)
Prolonged action potential duration drugs like
Amiodarone
sotalol
Class IV antiarrhythmics (2)
Calcium channel blockers like
Verapamil
diltiazem
Class Ia antiarrhytmic side effects
Nausea, vomiting
Quinidine: hemolytic anemia, thrombocytopenia, tinnitus
Procainamide: drug induced lupus
Class Ib antiarrhythmic side effects
Lidocaine: dizziness, confusion, seizures, coma
Mexiletine: tremor, ataxia, rash
Class Ic antiarrhythmic side effects
Flecainide: nausea, dizziness
Class II antiarrhytmic side effects
CHF, bronchospasm, bradycardia, hypotension
Class III antiarhythmic side effects
Amiodarone: hepatitis, pulmonary toxicity, thyroid disease, peripheral neuropathy
Sotalol: bronchospasm
Class IV antiarrhythmic side effects
AV block, hypotension, bradycardia, constipation
Precipitating causes of V-tach (5)
electrolyte imbalance
acid-base problems
hypoxemia
MI
drugs
Long QT can lead to this dangerous rhythm
Torsades de pointes
Drugs associated with torsades de pointes (9)
Tricyclic antidepressants
Erythromycin
Ketoconazole
haloperidol
cisapride
disopyramide
pentamidine
sotalol
Class I antiarrhythmics