Cardiorespiratory Physiology Flashcards
Tidal volume
1) Definition
2) Normal value
1) volume of normal inspiration and expiration
2) 7ml/kg
Minute ventilation
1) Definition
2) Normal value
1) volume of air inspired in 1 minute
2) Tidal volume x RR
Physiological dead space
1) Definition
2) Normal value
1) Total volume of gas not involved in gas exchange
2) Anatomical dead space + alveolar dead space
Anatomical dead space
1) Definition
2) Normal value
1) Volume of conducting airways not involved in gast exchange
2) 150ml
Lung compliance
Unit change in lung volume per unit change in pressure
Factors that lead to increase lung compliance
Emphysema
Factors leading to decrease lung compliance
Age
Supine
Increase ACS
Restrictive lung disease
Hydro/pneumothorax
Central chemoreceptors
1) location
2) mechanism
1) ventral surface of medulla
2) increase PaCO2 -> decrease pH of CSF -> increase ventilation
Peripheral chemoreceptors
1) location
2) mechanism
1) carotid body
2) stimulated to increaes ventilation when decrease PaO2/pH/increase PacO2
Oxygen Hb dissociation curve
1) x-axis
2) y-axis
3) Shape and why
1) Oxygen tension (PO2, mmHg)
2) Oxyhemoglobin (% saturation)
3) sigmoid, positive cooperativity of Hb
What shifts oxygen Hb dissociation curve to left?
increase pH
decrease temp
decrease DPG
What shifts oxygen Hb dissociation curve to the right?
decrease pH
increase temp
increase DPG
In pulse oximetry, absorption wavelength of
1) deoxyHb
2) oxyHb
1) 660nm
2) 940nm
Beer’s law
the concentration of a given solute in a solvent is determined by the amount of light that is absorbed by the solute at a specific wavelength
Lambert’s law
equal parts in the same absorbing medium absorb equal fractions of the light that enters them.
How is oxygen saturation calculated via pulse oximetry
Ratio of max/min absorption of infrared and red light