Cardioresp ( MISSED INFO ) Flashcards
1
Q
What inflammatory cells are found in asthma compared to COPD?
A
Eosinophils, Mast cells, T2 lymphocytes VS
Neutrophils, Macrophages, Tc1 Lymphocytes
2
Q
What mediators are involved in asthma?
A
IL-4, IL-5, CysLTs
3
Q
What mediators are involved in COPD?
A
TNF-a, IL-8, LTB4
4
Q
What are the treatments for Asthma compared to COPD?
A
Asthma : Bronchodilators + Corticosteroids
COPD : not those
5
Q
What is the pathology for Asthma?
A
Mucus plug in airway lumen = bronchoconstriction
Causes epithelial to become folded
6
Q
COPD pathology?
A
Chronic bronchitis : mucus hypersecretion
Extrapulmonary : mucus in main bronchus
Intrapulmonary : mucus in small diameter airway
- known as small airway disease - SAD
- can also be emphysemic
- chronic bronchitis
7
Q
What does it mean by COPD emphysema
A
Lung destruction
